DiePharmazie 2/2002

All contributions of this issue were presented during the 3rd Conference
on terometabolism Based Drug Design and Targeting, May 13-16,
2001, Amelia Island, Florida, USA



Szelenyi, I.; Pahl, A.: Drug therapy in asthma bronchiale in the new

Buchwald, P.; Bodor, N.: Physicochemical aspects of the enzymatic
hydrolysis of carboxylic esters

Brewster, M. E.; Loftsson, T.: The use of chemically modified
cyclodextrins in the development of formulations for chemical delivery

Murakami, T.; Yumoto, R.; Nagai, J.; Takano, M.: Factors affecting
the expression and function of P-glycoprotein in rats: drug treatments
and diseased states


Original articles

Buchwald, A.; Derendorf, H.; Ji, F.; Nagaraja, N.; Wu, W.-M.;
Bodor, N.
: Soft cannabinoid analogues as potential anti-glaucoma

Huang, F.; Wu, W.-M.; Ji, F.; Juhász, A.; Bodor, N.: Design,
pharmacokinetic, and pharmacodynamic evaluation of soft
anticholinergics based on tropyl a -phenylcyclopentylacetate

Tökes, B.; Suciu, G.; Nagy, G.: Interdependent
chemical-electrochemical steps in retrometabolism-based drug and
safer chemical design

Wanchana, S.; Yamashita, F.; Hashida, M.: Quantitative
structure/property relationship analysis on aqueous solubility using
genetic algorithm-combined partial least squares method

Whei-Mei Wu; Jiaxiang Wu; Bodor, N.: Effect of 2-hydroxypropyl-b
-cyclodextrin on the solubility, stability, and pharmacological activity of
the chemical delivery system of TRH analogs

Somogyi, G.; Buchwald, P.; Bodor, N.: Targeted drug delivery to the
central nervous system via phosphonate derivatives (Anionic delivery
system for testosterone)

Ji, F.; Wu, W.-M.; Bodor, N.: Studies on a soft glycopyrrolate analog,

Miklós, A.; Magyar, Z.; Kiss, É.; Novák, I.; Grósz, M.; Nyitray, M.;
Dereszlay, I.; Czégeni, E.; Druga, A.; Howes, J.; Bodor N.
: 28-Day
oral toxicity study with soft corticosteroid BNP-166 in rats and dogs,
followed by a 14-day recovery period

Short communication

Komuro, M.; Kakuo, H.; Sawada, K.; Kawaguchi, Y.: Novel
transdermal targeting in steroid therapy: Evaluation of PK/PD profiles
using an animal model of rheumatoid arthritis