DiePharmazie 9/2001



Fischer, J.; Gere, A.: Timing of analog research in medicinal chemistry


Original articles

Zega, A.; Trampus-Bakija, A.; Fortuna, M.; Stegnar, M.; Tschopp, T. B.; Steiner, B.; Urleb, U.: Novel thrombin inhibitors with azaphenylalanine scaffold

Venz, C.; Otto, H.-H.: ß-Lactam derivatives as enzyme inhibitors: Derivatives of (E)-2-[(RS)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-
3-ylidene]propionic acid

Meyer, T.; Lemcke, T.; Geffken, D.; Kaulfers, P.-M.: Synthesis and antibacterial activity of 5- and 6-hydroxy substituted 4-amino-quinolines and derivatives

Möhrle, H.; Niessen, R.: Ring cleavage of N-methoxypyridinium salts by amines (in German)

Hanna, G. M:; Lau-Cam, C. A.: A stability-indicating proton nuclear magnetic resonance spectroscopic method for the analysis of propantheline bromide in pharmaceutical samples

Schulz, B.; Stoeva, S.; Voelter, W.; Schmidt, P.C.: Analytical behavior of enzyme tablets (in German)

Vänttinen, K.; Moravcova, J.: Transdermal absorption of phytoestrogens

Halsas, M.; Penttinen, T.; Veski, P.; Jürjenson, Marvola, M.: Time-controlled release pseudoephedrine tablets: bioavailability and in vitro/in vivo correlations

Marschütz, M. K.; Puttipipatkhachorn, S.; Bernkop-Schnürch, A.: Design and in vitro evaluation of a mucodadhesive oral delivery system for a model polypeptide antigen

De Souza, T. P.; Bassani, V. L.; Gonzáles Ortega, G.; Dalla-Costa, T. C. T.; Petrovick, P. R.: Influence of adjuvants on the dissolution profile of tablets containing high doeses of spray-dried extract of Maytenus ilicifolia

Schubert, M. A.; Schubert, Müller-Goymann, C. C.: Solubilization of bromhexine hydrochloride in aqueous lecithin dispersions - physicochemical characterization of interactions between drug and carrier

Javernik, S.; Kreft, S.; Strukelj, B.; Vrecer, F.: Oxidation of lovastatin in the solid state and its stabilization with natural antioxidants

Bernhardt, M.; Sturm, C.; Shaker, K. H.; Paper, D. H.; Franz, G.; Seifert, K.: Structurally related immunological effects of triterpenoid saponins


Short communications

Dimmock, J.R.; Kumar, P.; Jha, A.; Quail, J.W.: Synthesis and cytotoxicity of 1-phenyl-3,3-diacetoxy-1-propene

Unterhalt, B.; Bagherzadeh, H.: A nitramin analog of ibuprofen (in German)

Loftsson, T.; Leeves, N.; Sigurjónsdóttir, J. F.; Sigurdsson, H. H.; Másson, M.: Sustained drug delivery system based on a cationic polymer and an anionic drug/cyclodextrin complex

Ianos-Irimie, M.; Deutsch, P.; Deutsch, G.: Renin – angiotensin system inhibitors – implications in the metabolism of the reactive oxygen species

Pande, V.: Antioxidant activity of rhamnazin-4’-O-ß-[apiosyl(1à )] glucoside in the brain of aged rats