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DiePharmazie 10/1995


Kubinyi, H.: Strategies and recent technologies in drug discovery

Original articles

Heber, D.; Herzig, S.; Moosig, F.; Neujahr, H.: Derivatives of 3-digitoxigenone amidinohydrazone: Synthesis and effect on the digitalis receptor of several species. Part 7: Compounds with positive inotropic activity

Dimmock, J.R.; Chamankhah, M.; Seniuk, A.; Allen, T.M.; Kao, G.Y.; Halleran, S.: Synthesis and cytotoxic evaluation of some Mannich bases of alicyclic ketones

Gütschow, M.; Tonew, E.; Leistner, S.: Bis[(2,4-dioxo-1,2,3,4-tetrahydrochinazoline-3-yl)alkyl]-disulfanes and 3-(mercaptoalkyl)quinazoline-2,4(1H,3H)-diones: Synthesis by ringtransformation and antiviral activity (in German)

Briel, D.: Thieno[2',3':3,4]pyrazolo[1,5-a]pyrimidines and -triazines: Synthesis of an unknown ring system (in German)

Dragovic, D.; Soskic, V.; Joksimovic, J.: Synthesis and evaluation of N,N-di-n-propyl-5,6,7,8-tetrahydro-1 H-benz[f]benzimidazol-6-yl-amine and related congeners as dopaminergic ligands

Görlitzer, K.; Roth, A.: Synthesis and reactions of 3,5-bis(methoxycarbonyl)-1,4-dihydro-2,6-dimethyl-4-nitrophenyl -1-pyridyl acetic acids (in German)

Hjorth Tonnesen, H.; Arrieta, A.F.; Lerner, D.: Studies on curcumin and curcuminoids. Part XXIV: Characterization of the spectroscopic properties of the naturally occurring curcuminoids and selected derivatives

Steiman, R.; Benoit-Guyod, J.L.; Guiraud, P.; Seigle-Murandi, F.: Evaluation of acrodontiolamide, a chlorinated compound produced by Acrodontium salmoneum de Hoog for cytotoxicity and antimicrobial activity

Repcák, M.; Mártonfi, P.: The variability pattern of apigenin glucosides in Chamomilla recutita diploid and tetraploid cultivars

Short communications

Plotkowiak, Z.; Popielarz-Brezezinska, M.: Specific acid catalysis in the breakdown of acyl derivatives of ampicillin

Dogrukol-Ak, D.; Tuncel, M.: Determination of omeprazole in capsules by certain polarographic techniques

Babincová, M.: Microwave-controlled drug release from magnetoliposomes

Zabka, M.; Benková, M.: Microemulsions containing local anaesthetics. Part 6: Influence of microemulsion vehicle on in vivo effect of pentacaine

Ryszka, F.; Krupej, J.; Dolinska, B.: Pharmacokinetics of calcitonin in rats with experimental osteoporosis

Stankovicová, M.; Králová, K.; Cizmárik, J.: The kinetics of alkaline hydrolysis of the new potential antiarrhythmic, substance H + B, in the presence of ß-cyclodextrin

Helia, O.; Pauliková, I.; Svajdlenka, E.; Devínsky, I.; Lacko, O.; Olaszova, E.: The hydrolytic activity of microsomal esterases: Organ-dependence and species variability

Jabbar, J.; Hasnat, A.; Bhuiyan, S.A.; Rashid, M.A.; Reza, S.: Isolation and in vitro antibacterial screening of a tricarboxylic acid anhydride from Penicillium sp.

Brieger, D.; Liedtke, S.; Weber, R.; Noll, T.; Kirschke, M.; Lichius, J.J.: A new ester glucoside derived from Digitalis lanata leaves: Maxoside (in German)

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