Original Articles

Morgenstern O., Giesen U., Garn T., Freitag M., Schmidt K., Großmann A., Trettin A., Thämlitz N., Lemmerhirt C.:
Investigations on 5,6,7,8-tetrahydro-[1,2,4]triazolo[1,2-a]pyridazin-1-amines and related compounds: synthesis, chemical behaviour, structure elucidation and iNOS inhibitory activity
doi: 10.1691/ph.2024.4524          (pp.130-145)

Pajaziti B. A., Andrási M., Nebija D., Kemlendi N., Pajaziti B.:
Optimization of a mass spectrometric analytical method for the quality assessment of insulin and its analogs
doi: 10.1691/ph.2024.4013          (pp.146-150)

Seradj D.-S., Neubauer L., Senekowitsch S., Weitschies W., Schick P.:
Metabolism of baicalin by different microbiota determined by MimiCol³
doi: 10.1691/ph.2024.4014          (pp.151-158)

Pilková A., Hartinger J. M., Malíková I., Satrapová V., Šťastná D., Tesař V., Slanař O.:
Management of apixaban anticoagulation in a patient requiring therapeutic plasma exchange: a case report and a literature review
doi: 10.1691/ph.2024.4550          (pp.159-162)

Nagase T., Shima O., Maruhana N., Miyazawa Y., Yoshino S., Sato J., Yamada H., Shinozaki K., Ikeda K.:
Analysis and evaluation of factors contributing to the occurrence of immune-related adverse events with immune checkpoint inhibitors
doi: 10.1691/ph.2024.4548          (pp.163-168)

Kato H., Koseki T., Kondo M.:
Occurrence of somnolence and respiratory depression induced by pregabalin and mirogabalin use and the influence of opioid treatment using the Japanese adverse drug event report database
doi: 10.1691/ph.2024.4528          (pp.169-172)

Nishiba H., Nagamine A., Yashima H., Takahashi Y., Higuchi Y., Sekizaki N.,
Nakamura H., Araki T., Takama N., Koitabashi N., Nakajima T., Kaneko Y., Ohyama Y., Effect of genetic factors on the interindividual variability of warfarin dosage requirements in Japanese patients after adjusting for renal function
doi: 10.1691/ph.2024.4546          (pp.173-177)

Original Articles

Taguchi K., Chuang V. T. G., Ozawa M., Sakamoto Y., Hara R., Iketani O., Enoki Y., Kizu J., Hori S., Matsumoto K.:
Anti-edematous effects of epinastine, cetirizine and its enantiomers in λ-carrageenan-induced edema in rat hind paw
doi: 10.1691/ph.2024.4518 (pp. 98-100)

Sleem M., Aboubakr E. M., Mohamed W. R., Messiha B. A. S., Taye A.:
Ameliorative effect of lixisenatide on diabetic cardiovascular damage and its enhancement via ticagrelor co-administration in rats: possible role of eNOS and NrF₂/HO-1 signaling
doi: 10.1691/ph.2024.4509 (pp. 101-108)

Krtinic D., Rankovic G. N., Petkovic I., Cvetanovic A., Conic I., Todorovic Mitic M., Radic M., Cevrljakovic M., Tosic Golubovic S., Binic I., Andjelkovic Apostolovic M., Jovanovic H., Trajkovic H., Milijasevic D., Mladenovic N., Lukic R.:
DN4 questionnaire as a useful tool for evaluating the pharmacotherapeutic response to opioid pharmacotherapy in malignant neuropathy
doi: 10.1691/ph.2024.4513 (pp. 109-113)

Yoshikawa N., Nagatomo T., Matsusaki Y., Yokota T., Yamada Y., Ikeda R:
Factors associated with changes in tacrolimus blood concentration after food initiation in patients with ulcerative colitis
doi: 10.1691/ph.2024.4501 (pp. 114-117)

Kawada K., Ishida T., Yoshioka T., Fukuda H., Hayashi T., Goda M., Ishizawa K.:
Association of non-steroidal anti-inflammatory drug use with encephalopathy development: An analysis using the United States Food and Drug Administration Adverse Event Reporting System (FAERS) and Japanese Adverse Drug Event Report (JADER) databases
doi: 10.1691/ph.2024.4506 (pp. 118-123)

Hirose T., Mori K., Kimura M., Yamashita S., Hayashi H., Usami E., Tanase T.:
Pharmacist-initiated interventions to test quantitative bone mineral density and prescribe osteoporosis medications to prevent steroid-induced osteoporosis
doi: 10.1691/ph.2024.4510 (pp. 124-128)

Review

Mohammed A. A., Alqahtani A. A., Ahmed M. M.:
Application of green synthesized silver nanoparticles in Burn therapy: a review
doi: 10.1691/ph.2024.3045 (pp. 42-48)

Original Articles

Kryeziu T., Bağci U., Loshaj-Shala A., Oral A., Stefkov GJ., Zimmer A., Basholli-Salihu M.:
Cytotoxic activity of liposomal Thymus Capitatus essential oil on HT-29 human colorectal cancer cell line
doi: 10.1691/ph.2024.3037 (pp. 49-56)

Muqaku L., Dorrer V., Noe M., Noe C. R., Nebija D., Marchetti-Deschmann M.:
Quality evaluation of highly purified human menopausal gonadotropin preparations by means of gel electrophoresis and mass spectrometry
doi: 10.1691/ph.2024.4003 (pp. 57-63)

Taguchi K., Chuang V. T. G., Ogino H., Hara R., Iketani O., Enoki Y., Kizu J., Hori S., Matsumoto K.:
Direct comparison of anti-inflammatory effects of 14-, 15-, and 16-membered macrolide antibiotics in experimental inflammation model induced by carrageenan in rats
doi: 10.1691/ph.2024.3667 (pp. 64-66)

Honma S., Handa K., Mitsumata R., Shimada D., Takei S., Tanaka G., Watanabe K., Yoshida M.:
Neurite outgrowth promotion in PC12 cells by 24(R)-ethyllophenol from Morus alba
doi: 10.1691/ph.2024.3656 (pp. 67-71) 

Runze Jin, Zitong Zhao, Qing Zhang, Yu Sun, Wei Wang, Daiyin Peng, Sihui Nian, Lingyun Zhou:
An anti-inflammatory active ingredients in Poriae cutis: Screening based on network pharmacology
doi: 10.1691/ph.2024.3647 (pp. 72-81)

Al Zaabi M. S. R., Sridhar S. B., Rabbani S. A., Tadross T. M., Shareef J., Shariff A.:
Antidepressant prescription patterns and polypharmacy in outpatient psychiatry: a cross-sectional study
doi: 10.1691/ph.2024.3663 (pp. 82-90)

Marinović I., Bačić Vrca V., Marušić S., Grgurević I., Brkić M., Jambrek N., Mesarić J., Samardžić I.:
Effect of care transfer model led by the hospital clinical pharmacist on reduction of hospital readmissions in the elderly
doi: 10.1691/ph.2024.3666 (pp. 91-96)

Original Articles

Kamiyama H., Nonaka C., Saitoh H., Ohno M., Shimizu Y., Isoda K.:
Anatase and rutile titanium oxide nanoparticles induce acute kidney injury by coadministration with paraquat, cisplatin or 5-aminosalicylic acid
doi: 10.1691/ph.2024.3655 (pp. 2-5)

Kasali F. M., Kadima J. N., Safari J. B., Agaba A. G., Tusiimire J., Witika B. A.:
Effects of Physalis peruviana L. (leaf crude extracts) on blood glucose and functional biomarkers in streptozotocin-nicotinamide-induced diabetic rats
doi: 10.1691/ph.2024.3640 (pp. 6-10)

Schuster J., Saddawi A., Frisch A., Heinitz K., Remane Y., Schiek S., Bertsche T.:
A comprehensive study of prescribing, administering and drug handling medication errors in ten wards of a university hospital after implementation of electronic prescribing, clinical pharmacists or medication reconciliation
doi: 10.1691/ph.2024.3579 (pp. 11-16)

Muraoka K., Sato M., Yonezawa R., Kurihara T., Higuchi S., Kogo M.:
Risk factors for postoperative nausea and vomiting after video-assisted thoracic surgery esophagectomy: a prospective cohort study
doi: 10.1691/ph.2024.3650 (pp. 17-23)

Kiyomiya K., Aomori T., Ohtani H.:
Comprehensive analysis of responses from ChatGPT to consumer inquiries regarding over-the-counter medications
doi: 10.1691/ph.2024.3628 (pp. 24-28)

Ezoe S., Ishihara T., Hosogai T., Kokubo T.:
Post-marketing surveillance of zinc acetate dihydrate for hypozincemia in Japan
doi: 10.1691/ph.2024.3630 (pp. 29-34)

Schmidt E.-M., Oetting M., Spiegel A., Zube O., Bertsche T.:
A clinical-pharmaceutical medication reconciliation with patient interview for a medication review to identify drug-related problems in elective patients during hospital admission
doi: 10.1691/ph.2024.3650 (pp. 35-40)

Original Articles

Taguchi K., Chuang V. T. G., Ozawa M., Sakamoto Y., Hara R., Iketani O., Enoki Y., Kizu J., Hori S., Matsumoto K.:
Anti-edematous effects of epinastine, cetirizine and its enantiomers in λ-carrageenan-induced edema in rat hind paw
doi: 10.1691/ph.2024.4518 (pp. 98-100)

Sleem M., Aboubakr E. M., Mohamed W. R., Messiha B. A. S., Taye A.:
Ameliorative effect of lixisenatide on diabetic cardiovascular damage and its enhancement via ticagrelor co-administration in rats: possible role of eNOS and NrF₂/HO-1 signaling
doi: 10.1691/ph.2024.4509 (pp. 101-108)

Krtinic D., Rankovic G. N., Petkovic I., Cvetanovic A., Conic I., Todorovic Mitic M., Radic M., Cevrljakovic M., Tosic Golubovic S., Binic I., Andjelkovic Apostolovic M., Jovanovic H., Trajkovic H., Milijasevic D., Mladenovic N., Lukic R.:
DN4 questionnaire as a useful tool for evaluating the pharmacotherapeutic response to opioid pharmacotherapy in malignant neuropathy
doi: 10.1691/ph.2024.4513 (pp. 109-113)

Yoshikawa N., Nagatomo T., Matsusaki Y., Yokota T., Yamada Y., Ikeda R:
Factors associated with changes in tacrolimus blood concentration after food initiation in patients with ulcerative colitis
doi: 10.1691/ph.2024.4501 (pp. 114-117)

Kawada K., Ishida T., Yoshioka T., Fukuda H., Hayashi T., Goda M., Ishizawa K.:
Association of non-steroidal anti-inflammatory drug use with encephalopathy development: An analysis using the United States Food and Drug Administration Adverse Event Reporting System (FAERS) and Japanese Adverse Drug Event Report (JADER) databases
doi: 10.1691/ph.2024.4506 (pp. 118-123)

Hirose T., Mori K., Kimura M., Yamashita S., Hayashi H., Usami E., Tanase T.:
Pharmacist-initiated interventions to test quantitative bone mineral density and prescribe osteoporosis medications to prevent steroid-induced osteoporosis
doi: 10.1691/ph.2024.4510 (pp. 124-128)

Review

Mohammed A. A., Alqahtani A. A., Ahmed M. M.:
Application of green synthesized silver nanoparticles in Burn therapy: a review
doi: 10.1691/ph.2024.3045 (pp. 42-48)

Original Articles

Kryeziu T., Bağci U., Loshaj-Shala A., Oral A., Stefkov GJ., Zimmer A., Basholli-Salihu M.:
Cytotoxic activity of liposomal Thymus Capitatus essential oil on HT-29 human colorectal cancer cell line
doi: 10.1691/ph.2024.3037 (pp. 49-56)

Muqaku L., Dorrer V., Noe M., Noe C. R., Nebija D., Marchetti-Deschmann M.:
Quality evaluation of highly purified human menopausal gonadotropin preparations by means of gel electrophoresis and mass spectrometry
doi: 10.1691/ph.2024.4003 (pp. 57-63)

Taguchi K., Chuang V. T. G., Ogino H., Hara R., Iketani O., Enoki Y., Kizu J., Hori S., Matsumoto K.:
Direct comparison of anti-inflammatory effects of 14-, 15-, and 16-membered macrolide antibiotics in experimental inflammation model induced by carrageenan in rats
doi: 10.1691/ph.2024.3667 (pp. 64-66)

Honma S., Handa K., Mitsumata R., Shimada D., Takei S., Tanaka G., Watanabe K., Yoshida M.:
Neurite outgrowth promotion in PC12 cells by 24(R)-ethyllophenol from Morus alba
doi: 10.1691/ph.2024.3656 (pp. 67-71) 

Runze Jin, Zitong Zhao, Qing Zhang, Yu Sun, Wei Wang, Daiyin Peng, Sihui Nian, Lingyun Zhou:
An anti-inflammatory active ingredients in Poriae cutis: Screening based on network pharmacology
doi: 10.1691/ph.2024.3647 (pp. 72-81)

Al Zaabi M. S. R., Sridhar S. B., Rabbani S. A., Tadross T. M., Shareef J., Shariff A.:
Antidepressant prescription patterns and polypharmacy in outpatient psychiatry: a cross-sectional study
doi: 10.1691/ph.2024.3663 (pp. 82-90)

Marinović I., Bačić Vrca V., Marušić S., Grgurević I., Brkić M., Jambrek N., Mesarić J., Samardžić I.:
Effect of care transfer model led by the hospital clinical pharmacist on reduction of hospital readmissions in the elderly
doi: 10.1691/ph.2024.3666 (pp. 91-96)

Original Articles

Kamiyama H., Nonaka C., Saitoh H., Ohno M., Shimizu Y., Isoda K.:
Anatase and rutile titanium oxide nanoparticles induce acute kidney injury by coadministration with paraquat, cisplatin or 5-aminosalicylic acid
doi: 10.1691/ph.2024.3655 (pp. 2-5)

Kasali F. M., Kadima J. N., Safari J. B., Agaba A. G., Tusiimire J., Witika B. A.:
Effects of Physalis peruviana L. (leaf crude extracts) on blood glucose and functional biomarkers in streptozotocin-nicotinamide-induced diabetic rats
doi: 10.1691/ph.2024.3640 (pp. 6-10)

Schuster J., Saddawi A., Frisch A., Heinitz K., Remane Y., Schiek S., Bertsche T.:
A comprehensive study of prescribing, administering and drug handling medication errors in ten wards of a university hospital after implementation of electronic prescribing, clinical pharmacists or medication reconciliation
doi: 10.1691/ph.2024.3579 (pp. 11-16)

Muraoka K., Sato M., Yonezawa R., Kurihara T., Higuchi S., Kogo M.:
Risk factors for postoperative nausea and vomiting after video-assisted thoracic surgery esophagectomy: a prospective cohort study
doi: 10.1691/ph.2024.3650 (pp. 17-23)

Kiyomiya K., Aomori T., Ohtani H.:
Comprehensive analysis of responses from ChatGPT to consumer inquiries regarding over-the-counter medications
doi: 10.1691/ph.2024.3628 (pp. 24-28)

Ezoe S., Ishihara T., Hosogai T., Kokubo T.:
Post-marketing surveillance of zinc acetate dihydrate for hypozincemia in Japan
doi: 10.1691/ph.2024.3630 (pp. 29-34)

Schmidt E.-M., Oetting M., Spiegel A., Zube O., Bertsche T.:
A clinical-pharmaceutical medication reconciliation with patient interview for a medication review to identify drug-related problems in elective patients during hospital admission
doi: 10.1691/ph.2024.3650 (pp. 35-40)

Original Articles

Kahsay B. N., Meiser S. L., Wohlrab J., Neubert R. H.H., Langguth, P.:
Delivery of free amino acids into and through the stratum corneum of the skin using micro emulsions and microemulsion-based hydrogels: Formulation, characterization, and ex-vivo permeation studies
doi: 10.1691/ph.2023.3011     (pp.177-184)

Bin Hu, Zhiliang Lv, Guiliang Chen, Jianzhong Lu:
Polymer selection for amorphous solid dispersion of a new drug candidate by investigation of drug polymer molecular interactions
doi: 10.1691/ph.2023.2061     (pp.185-195)

Ying-xin Yang, Ye-cheng Jin, Hua-qian Jin, Yan-mo Liu, Miao-fa Ying, Cheng-tao Jin,
Rui Zhao:
Astragaloside IV protects cardiomyocytes from hypoxic injury by regulating endoplasmic reticulum stress via elF2α/CHOP signaling pathway
doi: 10.1691/ph.2023.1946     (pp.196-200)

So M., Tsuji Y., Suzuki T.:
Efficacy of zinc acetate hydrate for hypozincemia in the elderly is influenced by the initial accumulated exposure dose after taking zinc acetate hydrate
doi: 10.1691/ph.2023.3576     (pp.201-206)

Kuchira R., Momo K., Kiryu Y., Sasaki T.:
Medication adherence of bisphosphonate weekly or monthly regimens in patients with osteoporosis using a nationwide large claims database
doi: 10.1691/ph.2023.3596     (pp.207-211)

Ogawa T., Arakawa M., Suzuki T., Yasuno N., Tanaka M., Hidaka S.:
Relationship between office blood pressure and actual antihypertensive drug use in patients with hypertension following the promulgation of the guidelines for hypertension (JSH2019)           doi: 10.1691/ph.2023.3587     (pp.212-215)

Original Articles

Knikman J E, de Vries Niels, Rosing H, Cats A, Guchelaar H J, Beijnen J H:
Development of a UPLC-MS/MS assay for the quantitative determination of capecitabine,
5’-deoxy-5-fluorocytidine (5’-dFCR), 5’-deoxy-5-fluorouridine (5’-dFUR), 5’-fluorouracil (5-FU), and α-fluoro-β-alanine (FBAL)
doi: 10.1691/ph.2023.3001       (pp.107-112)

Togami K, Zhan X, Ishizawa K, Miyakoshi K, Miyao A, Quan P, Chono S:
Development of LOX-1 antibody modified immuno-liposomes as drug carriers to macrophages in atherosclerotic lesions
doi: 10.1691/ph.2023.3004       (pp.113-116)

Amadutsumi T, Urashima Y, Urashima K, Suzuki K, Kurachi K, Nishihara M, Neo M,
Myotoku M, Kobori T, Obata T:
Semisolid enteral nutrients alter the pharmacokinetics of orally administered levetiracetam in rats
doi: 10.1691/ph.2023.3575       (pp.117-121)

Kralova E, Hadova K, Cinakova A, Krenek P, Klimas J:
Pioglitazone alters Ace/Ace 2 balance to favour Ace2 independently of glycaemia levels in diabetic rat heart
doi: 10.1691/ph.2023.3570       (pp.122-127)

Yamaki K, Tamura Y, Suzuki T, Uesaki Y, Dougan A, Koyama Y:
PI3K/mTOR inhibitor dactolisib attenuates allergic response through inhibitions of the sensitization and mast cell activation
doi: 10.1691/ph.2023.3519       (pp.128-133)

Wildhagen F V, Neininger M P, Hensen J, Steinbeck A, Zube O, Bertsche T:
An observational study to identify drug-related problems (DRP) in routine care and an expert panel assessment to rate clinical risk and preventability by unit-dose dispensing systems (UDDS) with computerized physician order entry (CPOE) and clinical decision-support systems (CDSS)
doi: 10.1691/ph.2023.3557       (pp.134-140)

Kose E, Nakagawa S, Niki K, Hashizume J, Kawazoe T, Suzuki N, Uchida M, Takase H:
Pharmacist interventions for adverse drug reactions in palliative care: A multicentre pilot study
doi: 10.1691/ph.2023.3554       (pp.141-149)

Freitag M, Bülow T, Fleig S, Eisert A, Krause O, Bollheimer L C, Laurentius T:
Continuation of geriatric discharge medication in primary care and its association with rehospitalizations – a cohort study
doi: 10.1691/ph.2023.3558       (pp.150-161)

Inić S, Gašparac P:
The Croatian translation of Flos medicinae: from health instructions with medicinal plants to contemporary phytotherapy
doi: 10.1691/ph.2023.3017       (pp.162-169)

Raal A, Gudiene V, Koshovyi O:
Professor Georg Dragendorff (1836 – 1898) as a toxicologist
doi: 10.1691/ph.2023.3008       (pp.170-175)

Review

Taleb MH: Phenytoin’s pharmacological interactions with medicinal herbs: a review
doi 10.1691/ph.2023.3546      (pp.77-81)

Original Articles

Doroudi A, Roayapalley PK, Das S, Das U, Dimmock JR: Are the cytotoxic properties of conjugated unsaturated ketones inactivated by thiols?
doi: 10.1691/ph.2023.3542     (pp.82-85)

Ito M, Xiaoxi L, Taguchi K, Enoki Y, Kuroda Y, Kizu J, Matsumoto K: Anti-inflammatory actions of expectorants in a rat carrageenan-induced footpad edema model
doi: 10.1691/ph.2023.3528     (pp.86-88)

Min Yeong Choi, Jeong Won Choi, Hyeok Jin Choi, Seung Woo Im, Gwang Hun Park, Jin Boo Jeong: Anti-obesity effects of Hovenia dulcis branches in mouse adipocytes, 3T3-L1 cells, and high-fat diet obese mice
doi: 10.1691/ph.2023.3518     (pp.89-92)

Takami K, Fukuda T, Yamatani A, Ikeuchi-Takahashi Y: Effect of diluents on active pharmaceutical ingredient loss until patients ingest powder formulation
doi: 10.1691/ph.2023.3544     (pp.93-99)

Nakamura S, Tanaka E, Iso Y, Fujihara H: Effect of sodium-glucose cotransporter-2 inhibitor administration on cardiac rehabilitation in patients with type 2 diabetes mellitus with heart failure
doi: 10.1691/ph.2023.3531    (pp.100-105)

Original Articles

Jirschitzka S, Girreser U, Kunze T: An aza-Michael addition product causes incompatibility between etacrynic acid and theophylline in a paediatric cardiological ICU
doi: 10.1691/ph.2023.2564 (pp. 27-30)

Xiaowei J, Lijuan Y, Yanling L, Qiuxiao L, Bohong G: Design and development of functionalized single-walled carbon nanotube-ethosomes for transdermal delivery of ketoprofen
doi: 10.1691/ph.2023.2572 (pp. 31-36)

Tsuchiya N, Okamoto K, Nakao S, Ohmori S, Shimizu T: Effect of blonanserin on the proliferation and migration of glioblastoma cells
doi: 10.1691/ph.2023.1821 (pp. 37-41)

Kose E, Yamamoto T, Tate N, Ando A, Enomoto H, Yasuno N: Adverse drug event profile associated with anti-dementia drugs: analysis of a spontaneous reporting database
doi: 10.1691/ph.2023.2584 (pp. 42-46)

Harabayashi R, Takahashi M, Takahashi K, Sugimoto T, Uchida J, Nakamura Y, Nagayama K: Safety profile of the concomitant use of atorvastatin and cyclosporine in renal transplant recipients
doi: 10.1691/ph.2023.2582 (pp. 47-50)

 Rémi C, Hermann A K, Hodiamont F, Bausewein C: Benefit of a palliative care drug information service and user experience: a cross-sectional study using a web-based online survey
doi: 10.1691/ph.2023.3501 (pp. 51-55)

Kawazoe T, Ishida T, Jobu K, Kawada K, Yoshioka S, Miyamura M: Analysis of urinary retention caused by selective β3-adrenoceptor agonists using the Japanese Adverse Drug Event Report database (JADER)
doi: 10.1691/ph.2023.3509 (pp. 56-62)

Onoda T, Tanaka H, Matsuo H, Takigawa M, Satoh M, Ishii T: Analysis of COVID-19 mRNA vaccine-induced mouth ulcers using the Japanese Adverse Drug Event Report database
doi: 10.1691/ph.2023.3521 (pp. 63-66)

Tayag J C S, Ishii T, Kokuba S, Hirata T, Shiohira H, Nakamura K: Effects of 5-fluorouracil co-administration on blood pressure in patients maintained on antihypertensives: a retrospective case series
doi: 10.1691/ph.2023.2579 (pp. 67-75)

Original Articles

Bin Sun, Xiaofei Liu, Xiuwei Sun, Yingjie Zhou, Xiaoqing Gong, Longfei Mao, Weichen Shi, Peng Deng, Lin Shi: Novel compounds with promising IDO1 inhibitory activity as new cancer drug candidates: Derivatives of
N,N’-diphenylurea linked with 1,2,3-triazole
doi: 10.1691/ph.2023.2552 (pp. 2-5)

Yoon Yeahwa, Bae Seunghee, Kim Tae Jin, An Sungkwan, Lee Jae Ho: Nodakenin inhibits melanogenesis via the ERK/MSK1 signaling pathway
doi: 10.1691/ph.2023.2490 (pp. 6-12)

Lei Jiang, Mingzhen Yang: Clinical efficacy and safety of flumatinib in newly diagnosed chronic myelogenous leukemia
doi: 10.1691/ph.2023.2536 (pp. 13-16)

Enners S, Gradl G, Kieble M, Iliescu O, Freudewald L, Said A, Schulz M: Increased demand for pharmaceutical drugs containing potassium iodide in connection with the Russia-Ukraine conflict
doi: 10.1691/ph.2023.2541 (pp. 17-19)

Raal A, Koppel J: 600 years of Town Hall Pharmacy (Raeapteek) in Tallinn, Estonia
doi: 10.1691/ph.2023.2065 (pp. 20-25)

Original Articles

Sutthapitaksakul L, Thanawuth K, Huanbutta K, Sriamornsak P: Effect of a superdisintegrant on disintegration of orally disintegrating tablets determined by simulated wetting test and in vitro disintegration test
doi: 10.1691/ph.2022.2015 (pp. 287-290)

Ying Xiong, Xinyue Zheng, Yongmei Xie, Youling Gong, Yi Luo: Effect of cyasterone on intestinal flora in a ^BRAFV600E-mutant mouse model of colorectal cancer
doi: 10.1691/ph.2022.2422 (pp. 291-294)

Alotaibe HF, Alolaiwi LA, Almutairi A, Alsubaie N, Badri M, Khafagy ES, Alotaibi HF: Association between levothyroxine replacement therapy and osteoporosis in Riyadh, Saudi Arabia: a matched case-control study
doi: 10.1691/ph.2022.2436 (pp. 295-298)

Ahmed NJ, Alsheri AM, Almalki ZS, Alahmari A: Drug-induced weight gain in the last 10 years: a descriptive study
doi: 10.1691/ph.2022.2408 (pp. 299-301)

Hindelang V, Dimitriadis K, Saller T, Golla K, Mannell H, Hug MJ, Strobach D: A new medication-based prediction score for postoperative delirium in surgical patients: Development and proof of feasibility in a retrospective patient cohort
doi: 10.1691/ph.2022.2438 (pp. 302-306)

Tanaka H, Okuma M, Ishii T: Occurrence of voriconazole-induced cutaneous squamous cell carcinoma in Japan: data mining from different national pharmacovigilance databases
doi: 10.1691/ph.2022.2453 (pp. 307-310)

Kohama Y, Kosugi M, Arakawa M, Hidaka S: Evaluating the impact of de-escalating antimicrobial therapy in burn patients: a retrospective cohort study
doi: 10.1691/ph.2022.2455 (pp. 311-315)

Original Articles

Guesmi H, Ben Kraim J, Alatrache A, Holzgrabe U: Hydrogen-deuterium (H/D) exchange reaction of acebutolol hydrochloride in D₂O and CD₃OD solution
doi: 10.1691/ph.2022.2419 (pp. 217-223)

Wenyi Li, Qiwei Chen, Weiwei Gao, Hui Zeng: ARID1A promotes chemosensitivity to gemcitabine I npancreatic cancer through epigenetic silencing of RRM2
doi: 10.1691/ph.2022.1881 (pp. 224-229)

Qian Zhou, Ting Chen: BI6727, a polo-like kinase 1 inhibitor, synergizes with gefitinib to suppress hepatocellular carcinoma cells via a G2/M arrest mechanism
doi: 10.1691/ph.2022.2392 (pp. 230-235)

Alavez-Pérez N, Patiño-Camacho IS, Granados-Soto V, Déciga-Campos M: Melatonin synergizes with the antinociceptive effect of N-palmitoylethanolamide and paracetamol
doi: 10.1691/ph.2022.2428 (pp. 236-242)

Yamashiro K, Hosomi K, Yokoyama S, Ogata F, Nakamura T, Kawasaki: Adverse event profiles of hypomagnesemia caused by proton pump inhibitors using the Japanese Adverse Drug Event Report (JADER) Database
doi: 10.1691/ph.2022.2416 (pp. 243-247)

Ohno H, Mano S, Katagiri N, Oguri R, Miyazaki K, Ito K, Sekiya Y, Inoue K, Masuda A, Tsuzuku A, Asano F, Hirashita T, Hayashi T: Influence of using history of immune checkpoint inhibitor therapy for neutropenia caused by combination therapy of ramucirumab and docetaxel
doi: 10.1691/ph.2022.2403 (pp. 248-254)

Uwai Y, Nabekura T: Analysis of adverse drug events in patients with bipolar disorders using the Japanese Adverse Drug Event Report database
doi: 10.1691/ph.2022.2386 (pp. 255-261)

Fujimori M, Nakamura M: Association between seasonal influenza vaccines and the increased risk of acute disseminated encephalomyelitis, estimated using the Vaccine Adverse Event Reporting System
doi: 10.1691/ph.2022.2354 (pp. 262-269)

Inić S, Gašparac P: Overview of Dioscorides’ recipes in Croatian books of folk recipes
doi: 10.1691/ph.2022.2027 (pp. 270-277)

Semedo MG, Pereira AL, Pita JR: Cinchona bark and quinine in the Portuguese official pharmacopoeias (1794-2001)
doi: 10.1691/ph.2022.2034 (pp. 278-285)

Original Articles

Kryeziu TL, Haloci E, Loshaj-Shala A, Bağci U, Oral A, Stefkov GJ, Zimmer A, Basholli-Salihu M: Nanoencapsulation of Origanum vulgare essential oil into liposomes with anticancer potential
doi: 10.1691/ph.2022.1230 (pp. 172-178)

Hehe Cui, Yuejin Yang, Xiangdong Li, Wenjing Zong, Qing Li: Resveratrol regulates paracrine function of cardiac microvascular endothelial cells under hypoxia/reoxygenation condition
doi: 10.1691/ph.2022.2370 (pp. 179-185)

So Yeon Kim, Yung-Yoon Kim, In Wook Kim, Hye-Young Yun, Dong-Seok Kim: LGl3 promotes human keratinocyte migration in high-glucose environments by increasing the expression of β-catenin
doi: 10.1691/ph.2022.2359 (pp. 186-190)

Ortíz-Rodríguez MA, Oaxaca-Navarro J, Patiño-Camacho SI, García-Jiménez S, Déciga-Campos M, Martínez-Salazar MF: Plasma levels of efavirenz and frequency of the CYP2B6 516G>T polymorphism in people living with HIV-1 in Mexico
doi: 10.1691/ph.2022.2382 (pp. 191-195)

Saito Y, Takekuma Y, Komatsu Y, Sugawara M: Evaluation of risk factors for chemotherapy-induced nausea and vomiting in cisplatin and gemcitabine treatment for biliary tract cancer: acid suppressants do not prevent nausea
doi: 10.1691/ph.2022.2355 (pp. 196-201)

Ichimura T, Ogawa C, Murata H, Miyahara K, Yuge S, Tsukioka R, Kado K, Yoshimura T, Suzuki K, Nomura H, Shimizu H: Community pharmacists’ measurement of health-related quality of life in outpatients taking high-risk drugs
doi: 10.1691/ph.2022.1914 (pp. 202-206)

Schilling S, Koeck JA, Kontny U, Orlikowsky T, Erdmann H, Eisert A: High-alert medications for hospitalised paediatric patients – a two-step survey among paediatric clinical expert pharmacists in Germany
doi: 10.1691/ph.2022.12025 (pp. 207-215)

Original Articles

Ushijima H, Onoder A: Selective growth suppressive effect of pravastatin on senescent human lung fibroblasts
doi: 10.1691/ph.2022.2327 (pp. 132-136)

Weiwei Zhou, Weizhe Liu, Dinyan Zhou, Aiying Li: ITGB1 suppresses autophagy through inhibiting the mTORC2/AKT signaling pathway in H9C2 cells doi: 10.1691/ph.2022.2351(pp. 137-140)

Hongxin Sun, Yumiko Urakami-Takebayashi, Hideyuki Motohashi, Junya Nagai: Internalization of FITC-albumin in human adipose-derived stem cells: Involvement of clathrin and caveolin
doi: 10.1691/ph.2022.2340 (pp. 141-146)

Yi-Lun Wang, Jin-Jie Yang, Wan Ni: Immunomodulatory effects of sinensetin on macrophage and cyclophosphamide-induced immunosuppression in mice
doi: 10.1691/ph.2022.2321 (pp. 147-151)

Hyunmin Ko, Young Il Kim, Hyung Joon Ahn: Activin suppresses the inflammatory response of TNF-α-stimulated human umbilical vein endothelial cells
doi: 10.1691/ph.2022.2330 (pp. 152-156)

Obayashi K, Nagamine A, Yashima H, Ohshima S, Uchiyama C, Takahashi E, Takahashi Y, Araki T, Yamamoto K: Comparison of the antiemetic effect of aprepitant/granisetron and palonosetron combined with dexamethasone in gynecological cancer patients treated with paclitaxel and carboplatin combination regimen
doi: 10.1691/ph.2022.12000 (pp. 157-161)

Fukuoka T, Yamamoto Y, Usami E, Hayashi H, Utsunomiya J, Kimura M, Nakamura M, Yoshimura T, Toda Y: Expression of peripheral neuropathy after vincristine treatment related to different administration methods
doi: 10.1691/ph.2022.2329 (pp. 162-164)

Kose E, Endo H, Hori H, Hosono S, Kawamura C, Kodama Y, Yamazaki T, Yasuno N: Association of pharmacist-led deprescribing intervention with the functional recovery in convalescent setting
doi: 10.1691/ph.2022.2323 (pp. 165-170)

Original Articles

Hossain M, Hall SC, Wiggington PJ, Roth SM, Das S, Das U, Roayapalley PK, Dimmock JR:  Cytotoic benzylidene hydrazides of terephthalic acid and related compounds
doi: 10.1691/ph.2022.11072 (pp. 90-94)

Al Azzam KM: A novel and simple dynamic coating capillary electrophoresis method for the chiral separation and quantification of mitiglinide entantiomers using hydroxyethyl cellulose as a dynamic coating agent
doi: 10.1691/ph.2022.1166 (pp. 95-102)

Miyazaki Y, Uchino T, Kagawa Y: Effect of batchsize on the granule properties in planetary centrifugal granulation
doi: 10.1691/ph.2022.11059 (pp. 103-106)

Huanbutta K, Thanawuth K, Sutthapitaksakul L, Ririyaprasarth S, Cheewatanakornkool K, Maksup S, Theeratanapartkul K, Sathorn P, Phusamlee P, Kwanjaiphanich T, Sangnim T, Sriamornsak P: Development and optimization of Clinacanthus nutans liquid spray using a two-level full factorial design
doi: 10.1691/ph.2022.1236 (pp. 109-112)

Yiwei Hu, Huiting Qu, Jie He, Hongyao Zhong, Shoukai He, Peng Zhao, Leyao Zhang, Jinghua Chen, Chao Deng: Human placental mesenchymal stem cell derived exosomes exhibit anti-inflammatory effects via TLR4-mediated NF-κB/MAPK and Pl3K signaling pathways
doi: 10.1691/ph.2022.11082 (pp. 113-118)

Nagai K, Fukuno S, Moriwaki R, Kuroda H, Omotani S, Miura T, Hatsuda Y, Myotoku M, Konishi H: Influene of concurrent and staggered dosing of semi-solid nutrients on the pharmacokinetics of orally administered carbamazepine in rats
doi: 10.1691/ph.2022.1756 (pp. 119-121)

Qiong Wang, Shenghan Gao, Wensheng Zhang, Yunxia Zhao, Yi He, Wei Sun, Fenglian Zhang, Tong Yu, Lihong Zhou, Zhengliang Ye, Jiansen Su, Shunnan Zhang, Yongfa Chen: Traditional use and safety evaluation of combination Traditional Chinese Medicine in European registration: with XiaoYao tablets as an example
doi: 10.1691/ph.2022.1227 (pp. 126-131)

Original Articles

Yang L, Higashisaka K, Haga Y, Tsujino H, Nagano K, Tsutsumi Y: Alpha-cystallin B chains enhance cell migration in basal-like 2 triple-negative breast cancer cells
doi: 10.1691/ph.2022.11019 (pp. 45-47)

Jian Tang, Zhenlong Zhou, Jun Qian, Xiaoling Lin, Qiwei Liu, Qiuling Xie, Sheng Xiong: KdPT alleviates imiquimod-induced psoriasis-like skin lesion in mice via inhibiting proliferation and inflammation resoponse
doi: 10.1691/ph.2022.1970 (pp. 48-53)

Kato R, Ijiri Y: Regorafenib and reactive metabolite of sunitinib activate inflammasomes: Implications for multi tyrosine kinase inhibitor-liduced immune related adverse events
doi: 10.1691/ph.2022.1955 (pp. 54-58)

Jianhua Li, Huanxian Wu, Shidong Lv, Dongling Quan, Danni Yang, Jiahuan Xu, Boyu Chen, Baofang Ou, Shaoyu Wu, Qiang Wei: Enhanced antitumor efficacy by combining afatinib with MDV3100 in castration-resistant prostate cancer
doi: 10.1691/ph.2022.1948 (pp. 59-66)

Bosch KE, Werner CJ, Rueckbeil MV, Eisert A: Use of electronic adverse drug reaction check to identify inpatients with a high drug-associated risk of falling: a case-control study at the Department of Neurology
doi: 10.1691/ph.2022.1807 (pp. 67-75)

Takikawa M, Tanaka H, Obara T, Maeda Y, Sato M, Shimazaki Y, Mori Y, Ishigami A, Ishii T: Utility of the Berlin Initiative Study-1 equation for the prediction of serum vancomycin concentration in elderly patients aged 75 years and older
doi: 10.1691/ph.2022.1972 (pp. 76-80)

Morii Y, Fujimoto S, Nakahara R, Okawa K, Senaha H, Fujiwara K, Tsubaki M, Matzno S, Takegami M, Shimomura K, Nishida S: Effect of proton pump inhibitors on the development of hypomagnesemia induced by panitumumab
doi: 10.1691/ph.2022.1988 (pp. 81-84)

Sugisaki T, Aoyama T, Kawakami K, Yokokawa T, Kobayashi K, Suzuki W, Ogura M, Ichimura T, Chin K, Yamaguchi K, Hanaoka S, Hayashi H, Yamaguchi M: Correlation between magnesium pre-loading and cisplatin-induced nephrotoxicity in
5­­-fluorouracil/cisplatin combination therapy for espohageal cancer
doi: 10.1691/ph.2022.11038 (pp. 85-88)

Original Articles

Sehner SM, Melzig MF: Fluorometric quantification of alkaloids in the homeopathic mother tinctures of Vinca minor L. and Fumaria officinalis L.
doi: 10.1691/ph.2022.1135 (pp. 2-5)

Miura M, Tanaka S, Ikedoa M, Kawakami J, Watanabe H, Namiki N, Uchida S: Increased plasma drug concentration and decreased additional insulin secretion following oral administration of glimepiride in Spontaneously Diabetic Torii rats
doi: 10.1691/ph.2022.1950 (pp. 6-8)

Hyun Sik Kang, Jin Yong Song, Jong Heon Kim, Tae Il Park, Won Seok Choi, Ji-Yun Lee: Effects of vinpocetine on atopic dermatitis after administration via three different routes in HR-1 hairless mice
doi: 10.1691/ph.2022.1941 (pp. 9-13)

Lixia Qiang, Zhiheng Li, Gongchen Wang, Xiangshun Li, Meiyu Lv, Baocai Wang, Zhaoquan Shi, Shoude Jin: Anti-TIM1 suppresses airway inflammation and hyperresponsiveness via the STAT6/STAT1 pathways in mice with allergic asthma
doi: 10.1691/ph.2022.1670 (pp. 14-20)

Yuankai Si, Zhigui Wu, Li Gu, Hua Li, Pei Ge, Wenxian Yin, Meijuan Chen: Changes of BKCA current and vascular reactivity in vascular smooth muscle of thoracic aorta and mesenteric artery in type 2 diabetic rats
doi: 10.1691/ph.2022.1740 (pp. 21-26)

Zupanets IA, Shebeko SK, Popov SB, Zupanets KO, Zimin SM: Analgesic properties of the dry combined extract BNO 1016 in leukotriene depended hyperalgesia
doi: 10.1691/ph.2022.0505 (pp. 27-31)

Xiao Yang, Shiyue Lang, Shuqi Li, Chunlai Jiang, Jiahong Han: Preparation of icariside l and icariside ll, an exploration of their protective mechanism against cyclophosphamide-induced bone marrow suppression in mice, and their regulatory effects on immune function
doi: 10.1691/ph.2022.1771 (pp. 32-37)

Seiberth S, Berner J, Hug MJ, Strobach D: `Double Whammy`and `Triple Whammy`combinations in hospitalized surgical patients – real life data from a tertiary teaching hospital
doi: 10.1691/ph.2022.1913 (pp. 38-43)

Review

Yang Su, Fan Zhang, Wen Qin, Lun Wu, Qiuhong Wang, Genhong Cheng, Haixue Kuang: “Gut-skin”axis: understanding psoriasis from the gut
doi: 10.1691/ph.2021.1694 (pp. 523-527)

Original Articles

 Pajaziti B, András M, Nebija D, Anastova L, Petkovska R: Chemometrics approach for optimization of capillary electrophoretic conditions for the separation of insulin analogues
doi: 10.1691/ph.2021.1758 (pp. 528-531)

Sobczyński J, Chudzik-Rząd B: The in vitro photocytotoxicity of photosensitizer encapsulated by nanovehicles comprising biomimetic phospholipids
doi: 10.1691/ph.2021.0047 (pp. 523-537)

Zhengqin Dong, Qianqian Feng, Han Zhang, Qiang Liu, Jianhua Gong: Curcumin enhances drug sensitivity of gemcitabine-resistant lung cancer cells and inhibits metastasis
doi: 10.1691/ph.2021.0927 (pp. 538-543)

Mengru Lu, Junli Liang, Jinyu Liang, Hepeng Li, Peng Yang: The effects of the renin inhibitor aliskiren on neuronal toxic damage
doi: 10.1691/ph.2021.1729 (pp. 544-550)

Jiangchao Zhuang, Xie Zhou, Ting Liu, Shuai Zhang, Falei Yuan, Leifang Zhang, Zuisu Yang, Yan Chen: Astaxanthin attenuated hyperuricemia and kidney inflammation by inhibiting uric acid synthesis and the NF-κB/NLRP3 signaling pathways in potassium oxonate and hypoxanthine-induced hyperuricemia mice
doi: 10.1691/ph.2021.1731 (pp. 551-558)

Lianlian Yang, Mingyan Jiang, Ruixin Yu, Ruolan Hu, Fei Xiong, Jinrong Li: A case report of precocious puberty related to Rett syndrome and a literature review
doi: 10.1691/ph.2021.1747 (pp. 559-561)

Strobach D, Schlattl A, Schieck S, Bertsche T: QTc-time-prolongating drugs and additional risk factors for long-QT-syndrome at hospital admission of surgical patients – risk assessment by pharmacists
doi: 10.1691/ph.2021.1697 (pp. 562-566)

Reviews

Abushammalla I: Tacrolimus and herbs interactions: a review
doi: 10.1691/ph.2021.1684 (pp. 468-472)

Yang Su, Jing Li, Lun Wu, Haixue Kuang: Polysaccharides from TCM herbs exhibit potent anti-obesity effect by mediating the community structure of gut microbiota
doi: 10.1691/ph.2021.1463 (pp. 473-479)

Original Articles

Ghasemisarabbadieh M, Sigurdsson SJ, Nu Dong FV, Gizurarson S, Sveinbjörnsson BR: The effect of D-(+)-glucosamine, N-acetyl-D-glucosamie and tetraethylene glycol on the stability of oxytocin in aqueous solution
doi: 10.1691/ph.2021.1081 (pp. 480-483)

Sekiguchi M, Sagano N, Kawazoe H, Hiraga Y, Jibiki A, Yokoyama Y, Suzuki S, Nakamura T: Drug repositioning of antipsychotic drugs for cisplatin-induced pica behavior in mice
doi: 10.1691/ph.2021.1674 (pp. 484-487)

Qi Li, Zhuqing Li, Tingting Li, Yanxin Wang, Jiaxin Feng, Chengzhi Lu: Efficacy and safety of soluble guanylate cyclase stimulators in patients with heart failure: A systematic review and meta-analysis
doi: 10.1691/ph.2021.1599 (pp. 488-493)

Xuemin Li, Long Yang, Shasha Zhang, Jie Shen: The molecular mechanism of the transcriptional activator SWI regulating gene ARID1B affecting swallowing dysfunction after stroke in rats
doi: 10.1691/ph.2021.1602 (pp. 494-498)

Lijun Tao, Lina Chen, Yanmin Pei, Ping Ma, Qinbin Xu, Jialing Wang, Yang Yu, Jiang Cheng, Ru Zhou: Vasodilatory effects of betaine on isolated rat pulmonary artery rings
doi: 10.1691/ph.2021.1392 (pp. 499-502)

Liuliu Pan, Xiaodan Zhang, Danhan Wang, Min Huang, Qiusui Huang, Ping Duan, Jie Mei: DCLK1 might be a therapeutic target of osthole against cervical cancer
doi: 10.1691/ph.2021.1641 (pp. 503-506)

Jing-Jing Yu, Fei Wu, Rui-Rui Ma, Tian-Jin Wu, Yuan Zhang, Zhen-Hua Ying: The effects of iguratimod combined with methotrexate and hydroxychloroquine on bone mineral density in patients with rheumatoid arthritis
doi: 10.1691/ph.2021.1630 (pp. 507-510)

Lin Zheng, Jiamin Du, Fujing Ge, Meijia Qian, Bo Yang, Qiaojun He, Qinjie Weng, Hong Zhu: The calcimimetic agent cinacalcet inhibits hepatocellular carcinoma via YAP/TAZ suppression
doi: 10.1691/ph.2021.1646 (pp. 511-514)

Ohyama K, Hirakawa K, Sasazaki K, Tanaka H, Hori Y, Takeuchi H: Time-to-onset of diabetes with everolimus use: analysis of a spontaneous reporting system database
doi: 10.1691/ph.2021.1624 (pp. 515-518)

Bach-Rojecky L, Lackovic Z: A century of phage therapy: from novel discoveries about the past to the challenges of the today
doi: 10.1691/ph.2021.1114 (pp. 519-521)

Review

Yangni Li, Yishu Zhang, Xuran Li, Yanfen Huang, Weiyan Chen, Lan He, Yuyan Zhang: Status of hypoxia-inducible factor-1α expression in non-small cell lung cancer
doi: 10.1691/ph.2021.1524 (pp. 404-411)

Original Articles

 Xuan GS, Zhan JH, Zhang AM, Li W, Zheng K: Inhibition of carbonic anhydrase ll by sulfonamide derivatives
doi: 10.1691/ph.2021.1590 (pp. 412-415)

Baba S, Yumoto R, Kawami M, Takano M: Functional expression of equilibrative and concentrative nucleoside transporters in alveolar epithelial cells
doi: 10.1691/ph.2021.1017 (pp. 416-421)

Yujiao He, Xiao Liu, Maolin Huang, Zheng Wei, Mengyu Zhang, Mengtao He, Zhebin Zheng, Hongbo Dong, Deming Liu: Oleanolic acid inhibits the migration and invasion of hepatocellular carcinoma cells by promoting microRNA-122 expression
doi: 10.1691/ph.2021.1366 (pp. 422-427)

Lulu Cao, Xiojia Lou, Lili Zhou, Yuedan Wu: The decrease of T3 / T4 is not hypothyroidism – a new mutation of Serpina7 gene results in partial thyroglobulin deficiency
doi: 10.1691/ph.2021.1559 (pp. 428-430)

Ning Cai, Qing Yang, Dao-Biao Che, Xin Jin: 20(S)-Ginsenoside Rg3 regulates the Hedgehog signaling pathway to inhibit proliferation and epithelial-mesenchymal transition of lung cancer cells
doi: 10.1691/ph.2021.1573 (pp. 431-436)

Fujimori M, Hasegawa S, Sasaoka S. Iguchi K, Nakamura M: A study of the association between seasonal influenza vaccines and the increased risk of Guillain-Barré syndrome using Vaccine Adverse Event Reporting System, 2018-2019
doi: 10.1691/ph.2021.1578 (pp. 437-443)

Yasuda M, Tachi T, Osawa T, Watanabe H, Inoue S, Makino T, Nagaya K, Morita M, Tanaka K, Aoyama S, Kasahara S, Teramachi H, Mizui T: Risk factors for thrombocytopenia and analysis of time to platelet transfusion after azacytidine treatment
doi: 10.1691/ph.2021.1566 (pp. 444-449)

Ichimura T, Nomura H, Shimizu H, Machida Y, Suzuki K: Cost-effectiveness of primary prophylaxis of febrile neutropenia with pegfilgrastim in docetaxel, cisplatin and 5-fluorouracil therapy for esophageal cancer
doi: 10.1691/ph.2021.1031 (pp. 450-454)

Wilhelmy S, Bekel AI, Gross D, Schmidt M: Forced to join the Waffen-SS? Chief pharmacist Victor Capesius (1907-1985) and his role in Auschwitz concentration camp
doi: 10.1691/ph.2021.1070 (pp. 455-460)

Petroianu GA, Lorke DE: Vinum resinatum: Scientists and unintended consequences
doi: 10.1691/ph.2021.1080 (pp. 461-466)

Reviews

Noe CR, Noe-Letschnig M: The role of ACE2 in the renin-angiotensin-system: Etiology and therapy of COVID-19 from a pharmaceutical perspective
doi: 10.1691/ph.2021.1618 (pp. 342-350)

Qun Feng, Zhiyan Huang, Ying Sun, Rong Sun, Guimin Zhang: Stilbene glucoside: recent advances in pharmacology, bioinformatics investigation, toxicity and future opportunities
doi: 10.1691/ph.2021.1393 (pp. 351-358)

Yining Zhao, Shuangmei Liu: Bioactivity of naringin and related mechanisms
doi: 10.1691/ph.2021.1504 (pp. 359-363)

Original Articles

Bao-Xin Li, Juan Lv, Xin Zhang, Can Zhang, Shu-Qin Guo, Rui-Jiang Ma, He Wang, Yun-Liang Zhang: Hypoglycemic effect of insulin-loaded hydrogel-nanogel composite on streptozotocin-induced diabetic rats
doi: 10.1691/ph.2021.1344 (pp. 364-371)

Shu-Yan Zhou, Xin-Yi Chen, Yan Chen, Na-Na Meng, Xin Tao, Hua-Long He, Zhi-Hao Liu, Ning-Yu Wang, Luo-Ting Yu: A novel fixed-dose combination treatment for chronic hepatitis C, based on NS5A inhibitor fopitasvir and NS5B inhibitor sofosbuvir
doi: 10.1691/ph.2021.0190 (pp. 372-378)

Zhenbin Li, Xuan Chen, Xiangjun Yi: The effects of A549 and H1299 cell-derived exosomes on the proliferation and apoptosis of BEAS-2B cells
doi: 10.1691/ph.2021.1513 (pp. 379-387)

Yuxin Chen, Yanqing Wu: Reverse remodeling in a heart failure patient with cardiomegaly treated with sacubitril/valsartan: a case report
doi: 10.1691/ph.2021.1546 (pp. 388-389)

Samardžić I, Marinović I, Kuča N, Bačić Vrca V: Potential clinically significant drug-drug interactions in prescribed pharmacotherapy in an outpatient setting
doi: 10.1691/ph.2021.1561 (pp. 390-395)

Semedo MG, Pereira AL, Pita JR: The influence of German science on Clinchona and quinine research in Portugal in the second half of the 19^th
doi: 10.1691/ph.2021.1050 (pp. 396-402)

Original Articles

Tae Kon Kim: Determination of SK7324, a new class of hepatitis C virus inhibitor, in rat plasma by UPLC-MS/MS and its application to the pharmacokinetic study of SK7324
doi: 10.1691/ph.2021.1442 (pp. 295-299)

Muhana F, Al-Ani I, Al-Akayleh F, Marzouqa D, Khalili F, Al-Khatib H, Mutti H, Shalan N: Synthesis and characterization of mesoporous silica and its application as drug delivery system for glimepiride
doi: 10.1691/ph.2021.1309 (pp. 300-307)

Zhou H, Xu P, Sun Y: Pharmacokinetics of abiraterone acetate released from a tablet based
on lipid matrix in beagle dogs
doi: 10.1691/ph.2021.0171 (pp. 308-312)

Kapelka I, Shtrygol S, Koiro O, Merzlikin S, Kudina O, Yudkevych T: Effect of arachidonic acid cascade inhibitors on body temperature and cognitive functions in rats in the Morris water maze after acute cold injury
doi: 10.1691/ph.2021.1571 (pp. 313-316)

Koeck JA, Mastragelopoulos N, Just KS, Eisert A: The prevalence of ‘triple whammy’ prescriptions in surgical inpatients and associated pharmacist recommendations
doi: 10.1691/ph.2021.1323 (pp. 317-327)

Kimura M, Usami E, Teramachi H, Yoshimura T: Identifying prognostic factors associated with overall survival in second-line paclitaxel plus ramucirumab treated human epidermal growth factor receptor 2-negative advanced/recurrent gastric cancer
doi: 10.1691/ph.2021.1432 (pp. 328-333)

Mori K, Yoshida M, Tomita K, Nakamura M, Yoshimura T: Intervention of dementia support team pharmacists and its effects for the proper use of rivastigmine
doi: 10.1691/ph.2021.1534 (pp. 334-337)

Ye Yang, Junjie Li, Ping Yu, Jun Ge, Bin Liu, Juan Li: A case of the third-line treatment of lung adenocarcinoma using nivolumab combined with anlotinib
doi: 10.1691/ph.2021.1420 (pp. 338-340)

Original Articles

Feng Bian, Yufeng Zhang, Yuanlong Xie, Hongyu Fang, Mingyu Fan, Xin Wang, Hongliang Li, Tao Huang, Sheng Zhang, Lin Cai: Effects of different concentrations of metformin on osteoclast differentiation and apoptosis and its mechanism
doi: 10.1691/ph.2021.1378 (pp. 244-248)

Fenxia Li, Kangli Zhang, Meng Yu, Tongtong Chen, Liyan Ma, Hongwu Zhang, Hongmei Jia, Zhongmei Zou: Antidepressant-like effect and phytochemical profile of supercritical CO2 extract from Citri reticulatae pericarpium
doi: 10.1691/ph.2021.1408 (pp. 249-255)

Lu Yuyu, Zhang Shikun, Zhang Zhenyu, Jiang Zongdan, Sun Weihao: MiR-877-5p targets PDK-1 to promote aspirin-induced apoptosis in gastric mucosal cells
doi: 10.1691/ph.2021.0926 (pp. 256-260)

Shimanuki Y, Hashimoto H, Kawazoe H, Uozumi R, Udagawa R, Watabe D, Nakamura T, Yamaguchi M,
Terakado H: Preventive effects of self-administered cryotherapy on paclitaxel-induced peripheral neuropathy in patients with early-stage breast cancer: a propensity score analysis
doi: 10.1691/ph.2021.1398 (pp. 261-265)

Arami T, Kawazoe H, Uozumi R, Hashimoto H, Egami S, Sakiyama N, Ohe Y, Nakada H, Aomori T, Ikemura S, Yasuda H, Kawada I, Fukunaga K, Soejima K, Yamaguchi M, Nakamura T: Effect of renin-angiotensin system inhibitors on pemetrexed plus platinum-induced hematological toxicities: a multicenter retrospective study using three propensity score analyses
doi: 10.1691/ph.2021.1409 (pp. 266-271)

Grgurević D, Grugurević J, Bačić Vrca V, Marušić S, Marinović I, Barić Grugurević A: Incidence of potential drug interactions in co-prescription of statins and macrolide antibiotics in Croatia during the 14 year period
doi: 10.1691/ph.2021.1412 (pp. 272-278)

Matsuyama T, Tachi T, Katsuno H, Sugioka M, Aoyama S, Osawa T, Koyama A, Murayama A, Noguchi Y,
Yasuda M, Mizui T, Goto C, Teramachi H: Effects of polypharmacy on the prevalence of adverse drug events resulting in outpatient visits and hospitalization
doi: 10.1691/ph.2021.1427 (pp. 279-286)

Pietryjia M, Kurkiewicz S, Kurkiewicz M, Błońska-Fajfrowska B:
Hermit Treutler’s Jerusalem Balsam
doi: 10.1691/ph.2021.1024 (pp. 287-293)

Original Articles

Hong Qiang, Jianbo Li, Shuaishuai Wang, Tiange Feng, Huijie Cai, Zhilei Liu, Jingjing Yuan, Wanli Zhang, Jinjie Zhang, Zhenzhong Zhang: Distribution of systemically administered nanoparticles during acute pancreatitis: effects of particle size and disease severity
doi: 10.1691/ph.2021.0156 (pp. 180-188)

Huang F, Marzin K, Koenen R, Kammerer KP, Strelkowa N, Elgadi M, Haertter S: Effect of itraconazole on the pharmacokinetics of faldaprevir in healthy subjects
doi: 10.1691/ph.2021.0197 (pp. 189-194)

Tianming Dai, Min Wang, Pengzhen Wang, Libing Dai, Renke Dai, Qingqi Meng: Inhibition effects of eight anti-coronavirus drugs on glycosides metabolism and glycosidases in human gut microflora
doi: 10.1691/ph.2021.01005 (pp. 195-201)

Xueshan Wen, Xing Zhang, Shulan Qu, Xugang Chen, Cheng Liu, Yifu Yang: Coptisine induces G2/M arrest in esophageal cancer cell via the inhibition of p38/ERK1/2/claudin-2 signaling pathway
doi: 10.1691/ph.2021.1353 (pp. 207-207)

Yu-Ye Xue, Yun-Yang Lu, Guang-Qiang Sun, Fei Fang, Yu-Qiang Ji, Hai-Feng Tang, Peng-Cheng Qiu, Guang Cheng: CN-3 induces mitochondrial apoptosis in glioma via Ros-mediated Pl3KAKT pathway
doi: 10.1691/ph.2021.1363 (pp. 208-214)

Caihong Hu, Zhengbo Liang, Ping Lai, Xiaofang Wang, Changming Zhao: Efficacy of atezolizumab to treat non-small-cell lung cancer: a meta-analysis based on randomized clinical trials
doi: 10.1691/ph.2021.1336 (pp. 215-219)

Shu Zhang, Xianzhi Xu, Yuanhong Huang, Siyuan Sun, Chengqi Jin, Hao Ji, Dong Sun, Anzhou Xia: Anisodamine ameliorates ischemia/reperfusion-induced renal injury in rats through activation of the extracellular signal-regulated kinase (ERK) pathway and anti-apoptotic effect
doi: 10.1691/ph.2021.1302 (pp. 220-224)

Chi-Ming Liu, Zhengping Wu, Bo Pan, Lijie An, Conglei Zhu, Jiqin Zhou, Yinjie Jiang: The antiandrogenic effect of neferine, liensinine, and isoliensinine by inhibiting 5-α-reductase and androgen receptor expression via Pl3K/AKT signaling pathway in prostate cancer
doi: 10.1691/ph.2021.1301 (pp. 225-231)

Bo Cui, Zhe Yang, Shuning Wang, Mengnan Guo, Qianqian Li, Qiuhua Zhang, Xiuli Bi: The protective role of protocatechuic acid against chemically induced liver fibrosis in vitro and in vivo
doi: 10.1691/ph.2021.0909 (pp. 232-238)

Fukuoka T, Yamamoto Y, Utsunomiya J, Usami E, Kimura M, Yoshimura T, Nakamura M, Tody Y: Association between immune-related dermatologic adverse events and efficacy of pembrolizumab in non-small cell lung cancer patients
doi: 10.1691/ph.2021.01018 (pp. 239-242)

Review

Bing Chen, Yishu Zhang, Simiao Chen, Xuran Li, Jingyi Dong, Weiyan Chen, Shuiliang Tao, Weiji Yang, Yuyan Zhang: The role of vascular endothelial growth factor in ischemic stroke
doi: 10.1691/ph.2021.1315 (pp. 127-131)

Original Articles

Haiping Yao, Yanyan Wang, Jiangwen Mo, Yan Peng, Zhu Wang: Design, synthesis, and biological evaluation of isoquinolin 1-(2H)-one derivates as tankyrase-1/2 inhibitors
doi: 10.1691/ph.2021.0904 (pp. 132-137)

Farias FF, Martins VAP, Dörr FA, Trujillo LM, Pinto E: Forced degradation study and characterization of main impurities of ibuprofen soft gelatin capsules by LC-MS-QTOF
doi: 10.1691/ph.2021.0126 (pp. 138-144)

Shuai Liu, Junfeng Zhu, Chang Liu, Jiazeng Li, Li Zhang, Jian Zhao, Hongsheng Liu: Synthesis of sustained release/controlled release nanoparticles carrying nattokinase and their application in thrombolysis
doi: 10.1691/ph.2021.0155 (pp. 145-149)

Mékidèche T, Curti C, Lamy E, Jean C, Bertault Peres P, Vanelle P: Compounding and quality control of two pediatric topiramate pharmaceutical preparations
doi: 10.1691/ph.2021.0176 (pp. 150-154)

Albassam AA, Ahad A, Alsultan A, Yusufoglu HS, Foudah AI, Al-Jenoobi FI: The inhibition of CYP1A2, CYP2C9, and CYP2D6 by pterostilbene in human liver microsomes
doi: 10.1691/ph.2021.1304 (pp. 155-158)

Juncheng He, Qifeng Zhou, Xianchao Jia, Peng Zhou, Lin Chen: Immune-related expression profiles of bisphosphonates-related osteonecrosis of the jaw in multiple myeloma
doi: 10.1691/ph.2021.01013 (pp. 159-164)

Zhujun Yin, Ruirong Tan, Tianmin Yuan, Shilong Chen, Yunyun Quan, Qing Hao, Jin Zeng, Junning Zhao, Li Li: Berberine prevents diabetic retinopathy through inhibiting HIF-1α/VEGF/NF-κB pathway in db/db mice
doi: 10.1691/ph.2021.0933 (pp. 165-171)

Yifan Chen, Min Zhang, Xinghao Ji, Jinjin Zhao, Shuang Qin, Yinghua Ji, Ruijuan Fan, Yanting Liu, Ping Lu: The anti-cancer effect of metoclopramide on triple-negative breast cancer cells
doi: 10.1691/ph.2021.0977 (pp. 172-174)

Kanabayashi Y, Amaya F, Ueno H, Tabuchi Y, Ishikawa T, Takayama K, Taguchi T: Factors affecting the effect of naldemedine for opioid-induced constipation: a single-institution, retrospective analysis
doi: 10.1691/ph.2021.0959 (pp. 175-178)

Reviews

Kumar SA, Weyland Cheng: A hypothesis: Bitter taste receptors as a therapeutic target for the clinical symptoms of SARS-CoV 2
doi: 10.1691/ph.2021.0840 (pp. 43-54)

Xin-xin Zhang, Dong-sheng Zhao, Jie Wang, Hui Zhou, Lei Wang, Jin-long Mao,
Ji-xiang He: The treatment of cardiovascular diseases: a review of ferulic acid and its derivatives
doi: 10.1691/ph.2021.0958 (pp. 55-60)

Xiao-Ming Xi, Chen-Meng, Shu-Jun Xia, Rong Liu: Drug loading techniques for
exosome-based drug delivery systems
doi: 10.1691/ph.2021.0128 (pp. 61-67)

Original Articles

Tavares HS, Cardoso JF, Almeida TC, Marques MBF, Mussel WN, Lopes MCP,
Oréfice RL, Andrade SN, Varotti FP, Silva GN, da Silva GR: Spiramyin-loaded PLGA implants for the treatment of ocular toxoplasmosis: development, characterization, biocompatibility, and anti-toxoplasma activity
doi: 10.1691/ph.2021.0100 (pp. 68-76)

Witika BA, Walker RB: Preformulation characterization and identification of excipients for nevirapine loaded niosomes
doi: 10.1691/ph.2021.0137 (pp. 77-83)

Tian Deng, Na Zhang, Yi Liu, Junmin Li: Daidzein ameliorates experimental acute reflux esophagitis in rats via regulation of cytokines
doi: 10.1691/ph.2021.01003 (pp. 84-91)

Shengli Li, Likun Sun, Qian Zhou, Shuo Li, Xiaoli Liu, Juan Xiao, Yaqi Xu, Fang Wang, Yang Jiang, Chengyun Zheng: Therapeutic effect and mechanism of ibrutinib combined with dexamethasone on multiple myeloma
doi: 10.1691/ph.2021.0917 (pp. 92-96)

Yan Hou, Yingli Zhen, Qingliang Xue, Wei Wang: Astragaloside lV attenuates
TGF-β-mediated epithelial-mesenchymal transition of pulmonary fibrosis via suppressing NLRP3 expression in vitro
doi: 10.1691/ph.2021.0933 (pp. 97-102)

Zhuoheng Lu, Shengtao Li, Jia Luo, Yishuang Luo, Manyun Dai, Xiuting Zheng, Jiapeng Qiu, Julin Yang, Aiming Liu: Fenofibrate reverses liver fibrosis in cholestatic mice induced by alpha-naphthylisothiocyanate
doi: 10.1691/ph.2021.0988 (pp. 103-108)

Renzhong Hu, Yijia Guo, Yapeng Lin, Yifang Tang, Qin Tang, Xiaoqing Wang, Jie Yang, Xia Wang: Safety and efficacy of edaravone combined with alteplase for patients with acute ischemic stroke: A systematic review and meta-analysis
doi: 10.1691/ph.2021.0949 (pp. 109-113)

Higashi T, Tsukamoto H, Kodawara T, Igarashi T, Watanabe K, Yano R, Iwasaki H,
Goto N: Evaluation of risk factors for nephrotoxicity associated with high-dose vancomycin
in Japanese patients
doi: 10.1691/ph.2021.0138 (pp. 114-118)

Inić S, Flegar V: Adolf Thierry and the first pharmaceutical factory in Southeast Europe
doi: 10.1691/ph.2021.0140 (pp. 119-125)

Original Articles

Kashiwagura Y, Uchida S, Hakamata A, Watanabe H, Namiki N: In vitro transdermal permeation and in vivo transdermal absorption of domperidone cream formulations compounded from tablets as a hospital formulation
doi: 10.1691/ph.2021.0082 (pp. 2-5)

Samardzic I, Marinovic I, Matkovic I, Mamic I, Bacic Vrca V: Antimicrobial drugs involved in potential drug-drug-interactions in cardiosurgical patients
doi: 10.1691/ph.2021.0774 (pp. 6-11)

Sze-Wan Wong E, Jingjing Li, Renkai Li R, Pak-Heng Leung G, Kwok-Fu Ng J: Involvement of different α₂ adrenoceptor subtypes in effects of dexmedetomidine on porcine coronary artery
doi: 10.1691/ph.2021.0878 (pp. 12-17)

Bing Hua, Hehe Cui, Qingbo Liu, Weiping Li, Hui Chen, Hongwei Li: Nicorandil protects cardiac microvascular endothelial cells from advanced glycation end products induced cytotoxicity via promoting autophagy
doi: 10.1691/ph.2021.0831 (pp. 18-22)

Ze Guo, Jinping Gao, Xing Fan, Anping Zhang, Zaixing Wang, Xianfa Tang, Yue Chen, Huayang Tang, Hui Li: Carbamazepine-induced DiHS/DRESS syndrome leading to hemophagocytic lymphohistiocytosis in a woman carrying the HLA-B*1301 gene
doi: 10.1691/ph.2021.0808 (pp. 23-26)

Yulin Wang, Run Cheng, Xinyi Wu, Mingxing Miao: Neuroprotective and neurotrophic effects of ginkgetin and bilobalide on MPTP-induced mice with Parkinson’ disease
doi: 10.1691/ph.2021.0799 (pp. 27-33)

Feng Xiao, Shi-Ming Zhang, Yan-Ping Wang: MiR-301a is interrelated with poor prognosis and contributes to temozolomide resistance in human glioma
doi: 10.1691/ph.2021.0814 (pp. 34-37)

Haoguang Ma, Yanjie Meng, Yanyan Wu, Xibiao Zhang, Chonghui Dan, Meimei Luo, Qiang Li: Inhibition of osteosarcoma cell proliferation by matrine (MT) via targeting histone H3 lysine 27 trimethylation and AMPK activation
doi: 10.1691/ph.2021.0718 (pp. 38-41)

Reviews

Chunyin Tang, Luxin Li, Jiayi Shi, Dan Wu, Meng Wang, Yan Wu, Xiaohuan Yuan: Curcumin in age-related diseases
doi: 10.1691/ph.2020.0760 (pp. 534-539)

Chao Z, Xiaochen S, Shuyue W, Xiao S, Yaohui Y, Fei G, Lei S:A review about industrialization of Chinese materia medica decoction pieces
doi: 10.1691/ph.2020.0647 (pp. 540-547)

Isawa M, Kajiyama M, Tominaga K, Nakada H, Aomori T, Mochizuki M: Review of clinical studies on the nocebo effect
doi: 10.1691/ph.2020.0642 (pp. 548-553)

Original Articles

Shinmachi K, Takahashi Y, Kaneuji Y, Kawamura R, Kohama K, Hieda Y, Goromaru T, Eto S, Murakami T, Maeda Y: Effect of aluminium ion on bioavailability of levofloxacin following oral administration of cilexetil ester of levofloxacin as prodrug in rats
doi: 10.1691/ph.2020.0601 (pp. 554-558)

Fang Yuan, Xiaolin Liang, Xiaoqing Chen, Xiaoling Qin, Changji Tan, Laiyou Wang: CYP2C19 is involved in the effect of Wuzhi tablet (Schisandra sphenanthera extract) and its constituents on the pharmacokinetics of intravenous voriconazole
doi: 10.1691/ph.2020.0635 (pp. 559-564)

Ji-Hye Ko, Nari Lee, Hyun-Kyu Kang, Bong Seok Kim, Jung No Lee, Chang-Gu Hyun: Anti-melanogenic effects of hot-water extracts from Torreya nucifera via MAPKs and cAMP signaling pathway on B16F10 cells
doi: 10.1691/ph.2020.0522 (pp. 565-570)

Fang Xie, Li Teng Jiajie Xu, Jianjian Lu, Chao Zhang, Liya Yang, Xiaoyang Ma, Minghao Zhao: Interleukin-10 modified bone marrow mesenchymal stem cells prevent hypertrophic scar formation by inhibiting inflammation
doi: 10.1691/ph.2020.0572 (pp. 571-575)

Shengjun Jiang, Liqin Xu: Exosomes from gingival mesenchymal stem cells enhance migration and osteogenic differentiation of pre-osteoblasts
doi: 10.1691/ph.2020.0652 (pp. 576-580)

Hailun Zheng, Ajie Zhang, Dapeng Li, Xiquan Ke, Qizhi Wang, Shanjun Yan, Yongju Xue, Xiaojing Deng: Aloperine can reverse the cisplatin resistance of colorectal cancer cells via suppressing the HIF-1α/ERK signaling pathway
doi: 10.1691/ph.2020.0672 (pp. 581-585)

Yirui Huang, Meijuan Xiao, Zusen Ye, Zhao Han, P. S. Reinach, Jianhua Cheng:
2-(-2-Benzofuranyl)-2-imidazoline reciprocally regulates Th17/Treg balance induced by ischemic stroke rats
doi: 10.1691/ph.2020.0634 (pp. 586-589)

Yan-Qiu Xu, Wen Lv, Hong-Juan Wu, Suo-Fang Shi: Ginsenoside regulates Treg/Th17 cell ratio and inhibits inflammation to treat COPD
doi: 10.1691/ph.2020.0696 (pp. 590-594)

Koshishi T, Koinuma M, Takagi A, Nakamura: Pharmacological considerations in antipsychotic drug selection for prevention of drug-induced dysphagia
doi: 10.1691/ph.2020.0735 (pp. 595-598)

Yokota T, Yoshikawa N, Arimori K, Ideda R: Retrospective analysis of risk factors for liposomal amphotericin B-associated nephrotoxicity
doi: 10.1691/ph.2020.0731 (pp. 599-601)

Kanabayashi Y, Amaya F, Ikoma K, Ueno H, Tabuchi Y, Ishikawa T, Takayama K, Taguchi T: Predictors of the usefulness of mirogabalin for neuropathic pain: a single-institution retrospective study
doi: 10.1691/ph.2020.0741 (pp. 602-605)

Lauze X, Mauriņa B, Šidlovska V: Pharmacy in Latvia during the occupation regime of Nazi Germany (1941-1945)
doi: 10.1691/ph.2020.0069 (pp. 606-610)

Kurkiewicz S, Pietryja MJ, Dzierzęga-Lęcznar A, Stępień K, Kurkiewicz M, Błońska-Fajfrowska B, Boryczka S: Contemporary analytical techniques reveal the secret composition of a 19^th century Jerusalem Balsam
doi: 10.1691/ph.2020.0098 (pp. 611-617)

Reviews

Noe CR, Handschuh P, Wolfslehner L, Noe CA, Noe-Letsching M, Soucek-Noe D, Lanzenberger R:
The “sugar dilemma”
doi: 10.1691/ph.2020.0684 (pp. 456-462)

Vlad RA, Hancu G, Ciurba A, Antonoaea P, Rédai EM, Todoran N, Silaşi O, Muntean DL:
Cannabidiol – therapeutic and legal aspects
doi: 10.1691/ph.2020.0076 (pp. 463-469)

Yan Ma, Yue Shen, Bin Zhu, Dan Li, Jiyong Liu: Application of nanotechnology in circumventing immunotolerance
doi: 10.1691/ph.2020.0040 (pp. 470-477)

Original Articles

Feng Wu, Xiuli Zhao, Siyang Ni, Bo Yang: A LC-MS/MS validated method for determination of azithromycin in human tears and its application to an ocular pharmacokinetic study
doi: 10.1691/ph.2020.0538 (pp. 478-482)

Lili Wang, Shuyu Liu, Ziyao Gao: Crystal structure, dissolution and hygroscopicity of a novel cocrystal hydrate of
berberine hydrochloride with L(+)-lactic acid
doi: 10.1691/ph.2020.0079 (pp. 483-487)

Nishida S, Hayashi Y, Hirai K, Takekoshi A, Yamada Y, Kobayashi R, Shimizu S, Niwa T, Hayashi H, Shimohata T, Sugiyama T, Suzuki A: Effect of therapeutic plasma exchange on phenytoin plasma concentration in patients receiving intravenous fosphenytoin therapy
doi: 10.1691/ph.2020.0525 (pp. 488-490)

Wei Ji, Hengli Zhao, Shaomei Yang, Qing Wen, Kun He: Pharmacokinetics and tolerability of intravenous pasaconazole in healthy Chinese volunteers: a randomized, open-label and single-dose study
doi: 10.1691/ph.2020.0512 (pp. 491-493)

Lejing Miao, Pei Yu, Jing Huang, Zehang Zhuang, Haihua Xiao, Zhiqiang Yu, Xiqiang Liu: Non-classical platinum-based compound 56MESS, with preferential cytotoxic effect on oral cancer cells by downregulating FACL4 expression
doi: 10.1691/ph.2020.0481 (pp. 494-499)

Jian-Feng Lu, Lian-Gang Qi, Xiao-Bo Zhu, Yi-Xin Shen: LncRNA RMRP knockdown promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-206/CDK9 axis
doi: 10.1691/ph.2020.0591 (pp. 500-504)

Qinlong Ji, Shanhong Qi, Chao Li, Xiangdong Kong, Qiang Zheng: Dexmedetomidine suppresses oxidative stress and inflammation of nucleus pulposus cells by activating the Pl3K/Akt signaling pathway
doi: 10.1691/ph.2020.9927 (pp. 505-509)

Nagai K, Fukuno S, Miura T, Uchino Y, Sehara N, Konishi H: Reduced cytotoxicity in doxorubicin-exposed HepG2 cells pretreated with menthol due to upregulation of P-glycoprotein
doi: 10.1691/ph.2020.0448 (pp. 510-511)

Shuo Wu, Yao Zhang, Yan Zhang, Lizhan Chen, Xi Xu, Yinli Dang, Xinyu Ti: Phillygenin regulates proliferation and apoptosis of non-small cell lung cancer through by AMPK/ERK/NF-κB axis
doi: 10.1691/ph.2020.0558 (pp. 512-515)

Wang Fu-Sang, Zheng Xiao-Han, Zou Yang, Chen Ting-Ting, Sun Chao, Ling Jing-Yi, Zou Jian-Jun: Efficacy and safety of dual versus mono antiplatelet therapy in patients with stroke or transient ischemic attack: An updated meta-analysis of 18 randomized controlled trials
doi: 10.1691/ph.2020.0683 (pp. 516-523)

Ohyama K, Arai H, Sugiura M, Hori Y: Psoriasis associated with ACE inhibitors: an analysis of the FAERS database
doi: 10.1691/ph.2020.0606 (pp. 524-526)

Kambara H, Hosohata K, Nakatsuji T, Ueno S, Oyama S, Inada A, Niinomi I, Wakabayashi T, Iwanaga K: Safety profile of vonoprazan compared with proton pump inhibitors: insight from a pharmacovigilance study
doi: 10.1691/ph.2020.0604 (pp. 527-530)

Letter to the editor

Ayoub BM, Ashoush N, Tadros MM, El Zahar NM, Hendy MS, Mowaka S: Rosuvastatin dose should be case individualized: An observation from inherited hypercholesterolemia case study
doi: 10.1691/ph.2020.0611 (pp. 531-532)

Original Articles

Xiao-Guang Yang, Yan-Feng Li, Yan-Jun Wang, Rui-Heng Kong, Dun Wang: Application of novel pH sensitive isoniazid-heptamethine carbocyanine dye conjugates against prostate cancer cells
doi: 10.1691/ph.2020.0521 (pp. 412-416)

Makoni PA, Kasongo KW, Walker RB: Preformulation studies of efavirenz with lipid excipients using thermal and spectroscopic techniques
doi: 10.1691/ph.2020.0053 (pp. 417-423)

Jiangfei Chen, Suhang Guo, Xianzhu Yu, Jinxiu Lei, Tao Xu, Suyan Zhu, Lu Chen,
Ping Xu, Xuan Zhou, Lushan Yu: Metabolic interactions between flumatinib and the CYP3A4 inhibitors erythromycin, cyclosporine, and voriconazole
doi: 10.1691/ph.2020.0068 (pp. 424-429)

Suiqiao Zhao, Chunyan Zhang, Zhuang Pi, Ruibing Li, Ping Han, Lixin Guo: Oxycodone protects cardiomyocytes from ischemia-reperfusion-induced apoptosis via Pl3K/Akt pathway
doi: 10.1691/ph.2020.0497 (pp. 430-435)

Jia Liu, Yu-Guang Wang, Shu-Yan Yu, Chun-E Li, Si-Meng Kang: Protective effect of acacetin in human periodontal ligament cells via regulation of autophagy and inflammation
doi: 10.1691/ph.2020.0435 (pp. 436-439)

Xuan Huang, Muchi Xu, Kejia Li, Fangxiu Luo, Haiqin Zhu: Nitidine chloride efficiently induces autophagy and apoptosis in melanoma cells via AMPK-mTOR signaling pathway
doi: 10.1691/ph.2020.0478 (pp. 440-442)

Arsić J, Krajnović D: Portable medicine chests and supply of medicines in Serbia from the 1830s to the mid-20^th century: analysis of medicines list
doi: 10.1691/ph.2020.0039 (pp. 443-454)

Original Articles

Otto F, van Hoogevest P, Syrowatka F, Heinl V, Neubert RHH: Assessment of the applicability of HLB values for natural phospholipid emulsifiers for preparation of stable emulsions
doi: 10.1691/ph.2020.9174 (pp. 365-370)

Togami K, Yamaguchi K, Tada H, Chono S: Assessment of transporter-mediated efflux of nintedanib using in vitro cell line models of idiopathic pulmonary fibrosis
doi: 10.1691/ph.2020.0048 (pp. 371-374)

Ayoub BM, Ramadan E, Ashoush N, Tadros MM, Hendy MS, Elmazar MM,  Mousa SA: Avoiding COVID-19 complications with diabetic patients could be achieved by multi-dose Bacillus Calmette-Guérin vaccine: a case study of beta cells regeneration
doi: 10.1691/ph.2020.0494 (pp. 375-380)

Ling Ma, Mei Zhong, Guihua Jiang, Fei Long, Weiling Wu, Yunbin Jiang: Elucidation of the active ingredients of Lamiophlomis herba against hemorrhage based on network pharmacology and tail snipping model in mice
doi: 10.1691/ph.2020.0507 (pp. 381-384)

Li Yuetong, Li Shangzhu, Hu Qinglin, Huang Pingping: Salidroside inhibits proliferation, migration and invasion of human pancreatic cancer PANC1 and SW1990 cells through the AKT and ERK signaling pathway
doi: 10.1691/ph.2020.0556 (pp. 385-388)

Fengli Zhang, Yanfen Yin, Tiantian Ni, Mei Zhang, Zhou Zhou, Xin Sun, Wanghao Kuang, Ping Li: Treatment effect of apatinib combined chemotherapy as second-line or above therapy in patients with advanced gastric cancer or adenocarcinoma of the gastroesophageal junction
doi: 10.1691/ph.2020.0403 (pp. 389-394)

Yunbo Fu, Yuanxiao Yang, Jianhong Shi, Kausik Bishayee, Luning Lin, Yiyou Lin, Yehui Zhang, Liting Ji, Changyu Li: Acori tatarinowii rhizoma extract ameliorates Alzheimer’s pathological syndromes by repairing myelin injury and lowering Tau phosphorylation in mice
doi: 10.1691/ph.2020.0492 (pp. 395-400)

Hui Gong, Ying Chen, Dongchu Zhou: Prognostic significance of metformin treatment in endometrial cancer: a meta-analysis
doi: 10.1691/ph.2020.0346 (pp. 401-406)

Xiang Yu, Na Li, Yayi Li: Were it business opportunities or hidden risks: Observations on clinical trials and marketing authorizations of Gilead Science’s remdesivir in China
doi: 10.1691/ph.2020.0549 (pp. 407-410)

Reviews

Friedrich C, Helmstädter A: Seventy-five volumes of  ֦^DiePharmazie֞ – a historical review
doi: 10.1691/ph.2020.0449 (pp. 289-293)

Röder E: Medicinal plants containing pyrrolizidine alkaloids in the New Kreuterbuch by Leonhart Fuchs (1543)
doi: 10.1691/ph.2020.0062 (pp. 294-298)

Raal A, Meos A, Hinrikus T, Heinämäki J, Romāne E, Gudienė V, Jakštas V, Koshovyi O, Kovaleva A, Fursenco C: Dragendorff’s reagent: Historical perspectives and current status of a versatile reagent introduced over 150 years ago at the University of Dorpat, Tartu, Estonia
doi: 10.1691/ph.2020.0438 (pp. 299-306)

Muankaew C, Saokham P, Jansook P, Loftsson T: Self-assembly of cyclodextrin complexes: detection,
obstacles and benefits
doi: 10.1691/ph.2020.0405 (pp. 307-312)

Original Articles

Li-Hua Wang, Lin Sui, Peng-Hui Zhao, Hai-Di Ma, Jia-Yuan Liu, Zhen Wei, Zai-Ji Zhan, Yong-Li Wang: A composite of graphene oxide and iron oxide nanoparticles for targeted drug delivery of temozolomide
doi: 10.1691/ph.2020.9170 (pp. 313-317)

Pan H, Li S, Li M, Tao Q, Jia J, Li W, Wang L, Guo Z, Ma K, Liu Y, Cui C: Anti-CD19 mAb-conjugated human serum albumin nanoparticles effectively deliver doxorubicin to B-lymphoblastic leukemia cells
doi: 10.1691/ph.2020.0026 (pp. 318-323)

Martínez-Rosas JR, Díaz-Torres R, Ramírez-Noguera P, López-Barrera LD, Escobar-Chavez JJ, Ángeles ER: PLGA nanoparticles of a new cinnamic acid derivative inhibits cellular proliferation on breast cancer cell line MCF-7 in a PPARγ dependent way
doi: 10.1691/ph.2020.0450 (pp. 324-328)

Takano M, Higashi M, Baba S, Kawami M, Yumoto R:
Transport of ribavirin in human myelogenous leukemia cell line K562
doi: 10.1691/ph.2020.0440 (pp. 329-334)

Yanhui Chu, Luxin Li, Yong Liu, Yan Wu, He Bai, Jieting Liu, Xiaohuan Yuan, Zhen Zhang:
FGF1 inhibits H₂O₂-induced mitochondrion-dependent apoptosis in H9c2 cells
doi: 10.1691/ph.2020.0427 (pp. 335-338)

Yamaki K, Terashi M, Ogura S, Inoue S, Naka N, Nakagaki T, Oka N, Koyama Y:
Anti-allergic effect of the Src family kinase inhibitor saracatinib
doi: 10.1691/ph.2020.9949 (pp. 339-343)

Juan Li, Xiao-Yu Cheng, Hui Yang, Li Li, Yang Niu, Jian-Qiang Yu, Wei-Qi Li, Yao Yao: Matrine ameliorates cognitive deficits via inhibition of microglia mediated neuroinflammation in an Alzheimer’s disease mouse model
doi: 10.1691/ph.2020.0395 (pp. 344-347)

Lili Yang: Physcion 8-O-β-glucopyranoside exerts carcinostasis ability in Ishikawa cells via regulating Inc-SLC4A1-1/H3K27ac/NFκB pathway
doi: 10.1691/ph.2020.9608 (pp. 348-352)

Reviews

Wei Li, Kewei Yu, Shujuan Sun: Novel oral hypoglycemic agents SGLT-2 inhibitors: cardiovascular benefits and potential mechanisms
doi: 10.1691/ph.2020.9634 (pp. 224-229)

Wei Li, Xiaoqing Zhang, Yan Sun, Zhaohua Liu: Recent clinical advances of glucokinase activators in the treatment of diabetes mellitus type 2
doi: 10.1691/ph.2020.0409 (pp. 230-235)

Original Articles

Tanaka S, Uchida S, Hakamata A, Miyakawa S, Odagiri K, Inui N, Watanabe H, Namiki N: Simultaneous LC-MS analysis of plasma concentrations of sildenafil, tadalafil, bosentan, ambrisentan, and macitentan in patients with pulmonary arterial hypertension
doi: 10.1691/ph.2020.0021 (pp. 236-239)

Novak A, Gutiérrez-Zamora M, Pérez-Lozano P, Suñé-Negre JM, Llop JM, Ticó JR, Miñarro M, García-Montoya E, van Schepdael A: Study of tocopherol content and its potential antioxidant activity in commercial lipid emulsions for parenteral nutrition
doi: 10.1691/ph.2020.0038 (pp. 240-241)

Yonghe Wang, Yunxia Zheng, Yuchen Hao: Rucaparip (Rubraca^®) induces necrosis via upregulating the expression of RIP1 and RIP3 in ovarian cancer cells
doi: 10.1691/ph.2020.9827 (pp. 242-245)

Jia-Lu Zheng, Shuang-Shuang Wang, Ke-Ping Shen, Xiao-Wei Huang, Miao Li, Lei Chen, Xiao Peng, Hong-Mei An, Bing Hu: Ursolic acid potentiated oxaliplatin to induce apoptosis in colorectal cancer RKO cells
doi: 10.1691/ph.2020.0417 (pp. 246-249)

Zhixin Liu, Youjie Li, Gaohan She, Xiaofeng Zheng, Liying Shao, Pingyu Wang, Min Pang, Shuyang Xie, Yunxiao Sun: Resveratrol induces cervical cancer HeLa cell apoptosis through the activation and nuclear translocation promotion of FOXO3a
doi: 10.1691/ph.2020.0386 (pp. 250-254)

Yifeng Ni, Hao Zhang, Jing Zhang, Zhi Li, Zubing Li: Inhibition of JAK2 by AG490 promotes TNF-α-induced apoptosis by inhibiting autophagy in MC3T3- E1 cells
doi: 10.1691/ph.2020.0375 (pp. 255-260)

Rui Wu, Xi Yang, Qian Zhou, Wenyan Yu, Minwei Li, Jianer Wo, Weiguang Shan, Hong Zhao, Yan Chen, Zhajun Zhan: Aurovertin B exerts potent antitumor activity against triple-negative breast cancer in vivo and in vitro via regulating ATP synthase activity and DUSP1 expression
doi: 10.1691/ph.2020.0380 (pp. 261-265)

Yuanyuan Duan, Yan Zhang, Wen Peng, Pengcheng Jiang, Zhaoqun Deng, Chenguang Wu: MiR-7-5p and miR-451 as diagnostic biomarkers for papillary thyroid carcinoma in formalin-fixed paraffin-embedded tissues
doi: 10.1691/ph.2020.0335 (pp. 266-270)

Wanqiang Chen, Shaohong Li, Qi Liu, Yusheng Yang, Lushan Wei, Yaqin Lu: MicroRNA-342-5p protects against myocardial ischemia-reperfusion injury by targeting the GPRC5A pathway
doi: 10.1691/ph.2020.0383 (pp. 271-274)

Na-Na Li, Tao Cao, Fei Yu, Lian Luo, Ping Liu: MiR-520c-3p alleviates LPS-induced A549 cell and mice lung injury via targeting NLRC5
doi: 10.1691/ph.2020.0355 (pp. 275-278)

Ueki T, Sanematsu E, Furuya Y, Shinohara Y, Murakami Y, Miyazaki A, Sakamoto Y, Nakashima MN, Nakashima M: Relationship between vancomycin-associated nephrotoxicity and the number of combined nephrotoxic agents
doi: 10.1691/ph.2020.0393 (pp. 279-283)

Lei Zheng, Ye Han, Yuyao Guan, Xiaoli Zhang, Chao Song, Jing Yang: Risks in clinical applications of oseltamivir phosphate in the real world
doi: 10.1691/ph.2020.0352 (pp. 284-287)

Review

Zhang W, Zhang P, Wang G, Cheng W, Chen J, Zhang X: Recent advances of therapeutic targets and potential drugs of COVID-19
doi: 10.1691/ph.2020.0431 (pp. 161-163)

Original Articles

Maree S, du Preez JL, du Plessis LH, du Plessis J, Gerber M: A novel HPLC method developed and validated for the detection and quantification of atorvastatin, fluvastatin, pitavastatin and pravastatin during transdermal delivery studies
doi: 10.1691/ph.2020.0007 (pp. 164-166)

Pajaziti B, Petkovska R, Andrási M, Nebija D: Application of the capillary zone electrophoresis (CZE) and capillary gel electrophoresis (CGE) for the separation of human insulin, insulin lispro and their degradation products
doi: 10.1691/ph.2020.9188 (pp. 167-171)

Ezquer-Garin C, Ferriols-Lisart R, Martinez-López LM, Sangrador-Pelluz C, Nicolás-Picó J, Alós-Almiñana M: Stability of tedizolid phosphate-sodium rifampicin and tedizolid phosphate-meropenem admixtures in intravenous infusion bags stored at different temperatures
doi: 10.1691/ph.2020.9155 (pp. 172-176)

Isagawa S, Shiohira H, Hokama N, Nitta H, Yoshida T, Masamoto H, Aoki Y, Nakamura K: Measurement of zinc concentration in blood and breast milk of a Wilson’s disease patient taking zinc acetate
doi: 10.1691/ph.2020.9765 (pp. 177-178)

Miyashiro CA, Bernegossi J, Bonifácio BV, de Toledo LG, Ramos MAS, Bauab TM, Chorilli M: Development and characterization of a novel liquid crystalline system containing sodium alginate for incorporation of trans-resveratrol intended for treatment of buccal candidiasis
doi: 10.1691/ph.2020.9165 (pp. 179-185)

Yanjie Qin, Nanxi Wang, Fen Chen, Xuemei Han, Ying Zhu, Ying Rang, Xuejia Zhai, Yongning Lu: Effects of cyclosporine A on the pharmacokinetics and toxicities of irinotecan mediated by UGT1A1 in vitro and in vivo
doi: 10.1691/ph.2020.0316 (pp. 186-190)

Ishida T, Morisawa S, Iizuka M, Fujita H, Jobu K, Morita Y, Miyamura M: Juzentaihoto extract suppresses adipocyte hypertrophy and improves hyperglycemia in KKAy mice
doi: 10.1691/ph.2020.9950 (pp. 191-194)

Yan-Yang Jin, Si-Qiao Tong, Ming Tong: Erdafitinib exerts the anticancer effect on urothelial carcinoma via induction of autophagy
doi: 10.1691/ph.2020.9911 (pp. 195-197)

Congcong Yu, Liuliu Pan, Guangbao Wang, Ziyao Cai, Yancan Zhou, Xuyong Zheng, Ce Chen, Xiaodan Zhang: Silybin enhances the blood concentration of brexpiprazole in rats by downregulating expression of CYP3A4 and CYP2D6
doi: 10.1691/ph.2020.9935 (pp. 198-200)

Meng-Jiao Du, Jian-Ping Chen, Bo-Wen Lian, Wen-Jie Mei, Jia-Xian Yu, Li-Shi Chen, Shan-Bin Deng, Yan-Mei Zhong, Chu-Qin Yu: Cardioprotective effects of timosaponin B-ll isolated from Anemarrhena rhizome in a zebrafish model
doi: 10.1691/ph.2020.9869 (pp. 201-204)

Suzuki K, Sato Y, Nakahara R, Tatsuta R, Tanaka R, Itoh H: Venous thromboembolisms and rheology in ovarian cancer patients after postoperative adjuvant paclitaxel and carboplatin therapy
doi: 10.1691/ph.2020.9908 (pp. 205-207)

Li LY, Ma L, Dong WL: Total glucosides of paeony (Paeonia lactiflora) alleviates blood-brain barrier disruption and cerebral ischemia/reperfusion injury in rats via suppressing inflammation and apoptosis
doi: 10.1691/ph.2020.0324 (pp. 208-212)

Yifeng Ni, Hao Zhang, Zhi Li, Zubing Li: Connective tissue growth factor (CCN2) inhibits TNF-α-induced apoptosis by enhancing autophagy through the Akt and Erk pathways in osteoblasts
doi: 10.1691/ph.2020.0336 (pp. 213-217)

Yamashita K, Ogihara T, Hayashi M, Nakagawa T, Ishizaki Y, Kume M, Yano I, Niigata R, Hiraoka J, Yasui H, Nakamura T: Association between dexamethasone treatment and alterations in serum concentrations of trace metals
doi: 10.1691/ph.2020.0341 (pp. 218-222)

Review

Di Liu, Yun-Zhao Li, Hui Wu, Jun Yang, Jian Yang, Jia-Wang Ding, Jing Zhang, Zhi-Xing Fan, Chao-Jun Yang: Duration of dual antiplatelet therapy after percutaneous coronary intervention with implantation of second-generation drug-eluting stent: A meta-analysis of randomized controlled trials
doi: 10.1691/ph.2020.0301 (pp. 113-117)

Original Articles

Zengjun Wang, Zhuowei Zhao, Nauman Rahim Khan, Zhen Hua, Junyi Huo, Yanhui Li: Microwave assisted chitosan-polyethylene glycol hydrogel membrane synthesis of curcumin for open incision wound healing
doi: 10.1691/ph.2020.9179 (pp. 118-123)

Tianyu Chen, Tianqiang Wu, Ningxi Li, Yichun Jiang, Huanli Yin, Min Wu: Simulation-based comparison of Biopharmaceutics Classification System and drug structure
doi: 10.1691/ph.2020.9874 (pp. 124-130)

Qiying Shen, Huan Shu, Xiaoling Xu, Gaofeng Shu, Yongzhong Du, Xiaoying Ying: Tofacitinib citrate-based liposomes for effective treatment of rheumatoid arthritis
doi: 10.1691/ph.2020.9154 (pp. 131-135)

Roosendaal J, Venekamp N, Lucas L, Rosing H, Beijnen JH: Development and validation of an LC-MS/MS method for the quantification of imatinib and imatinib-d8 in human plasma for the support of an absolute bioavailability microdose trial
doi: 10.1691/ph.2020.9150 (pp. 136-141)

Miao Li, Shu-Mei Wang, Wan-Shui Wu, Dan Yan, Le-Ping Zhang, Hu-Yong Zheng: Frequency distribution of five SNPs in human GGH gene and their effects on clinical outcomes of Chinese pediatric patients with acute lymphoblastic leukemia
doi: 10.1691/ph.2020.9932 (pp. 142-146)

Yi-Zhen Tian, Ya-Peng Liu, San-Chun Tian, Su-Yin Ge, Yong-Jie Wu, Bao-Lai Zhang: Antitumor activity of ginsenoside Rd in gastric cancer via up-regulation of Caspase-3 and Caspase 9
doi: 10.1691/ph.2020.9931 (pp. 147-150)

Niinomi I, Hosohata K, Oyama S, Inada A, Wakabayashi T, Iwanaga K: Evaluation of adverse events associated with filgrastim originator and biosimilar using a spontaneous reporting system database
doi: 10.1691/ph.2020.9189 (pp. 151-153)

Usami E, Kimura M, Takenaka S, Kanda T, Teramachi H, Yoshimura T: Continuity and efficacy of real-world use of azacitidine
doi: 10.1691/ph.2020.9905 (pp. 154-158)

Letter to the editor

Yaoub, BM: COVID-19 vaccination clinical trials should consider multiple doses of BCG
doi: 10.1691/ph.2020.044 (p. 159)

Reviews

Ruqiao L, Yueli C, Xuelan Z, Huifen L, Xin Z, Danjie Z, Le S, Yanxue Z: Rhizoma Atractylodis macrocephalae: a review of photochemistry, pharmacokinetics and pharmacology
doi: 10.1691/ph.2020.9738 (pp. 42-55)

Rashid ZA, Al-Tabakha MM, Alomar MJ: Community pharmacist’s’ knowledge and practice toward oral isotretinoin prescription: a systemic review
doi: 10.1691/ph.2020.9891 (pp. 56-60)

Original Articles

Georgieva Y, Kassarova M, Kokova V, Apostolova E, Pilicheva B: Taste masking of enalapril maleate by microencapsulation in Eudragit EPO^® microparticles
doi: 10.1691/ph.2020.9123 (pp. 61-69)

Pala Kara Z, Ozturk D, Ozturk N, Orman MN, Baktir G, Okyar A: Effects of atorvastatin on talinolol absorption: A potential drug-drug interaction
doi: 10.1691/ph.2020.9904 (pp. 70-74)

Cavalcante Loureiro K, Carvalho Barbosa T, Nery M, Vinicius Chaud M, Ferreira da Silva C, Nalone Andrade L, Bani Corrêa C, Jaguer A, Ferreira Padilha F, Cordeiro Cardoso J, Souto E, Severino P: Antibacterial activity of chitosan/collagen membranes containing red propolis extract
doi: 10.1691/ph.2020.9050 (pp. 75-81)

Hanaoka S, Endo A, Hayashi H, Hirai T, Seki T: Histamine-2 receptor antagonists (H₂RA) may negatively impact ADL assessment in patients on a convalescent rehabilitation ward
doi: 10.1691/ph.2020.9858 (pp. 82-89)

Qunli Meng, Caixa Ye, Yaqin Lu: miR-181c regulates ischemia/reperfusion injury-induced neuronal cell death by regulating c-Fos signaling
doi: 10.1691/ph.2020.9856 (pp. 90-93)

Xing Wang, Leyi Li, Sinan Pei, Qian Zhu, Feihong Chen: Disruption of SSBs repair to combat platinum resistance via the JWA-targeted Pt(IV) prodrug conjugated with a wogonin derivative
doi: 10.1691/ph.2020.9815 (pp. 94-101)

Ma L, Li LY, Zhao TL: Anti-inflammatory effects of ginsenoside Rg3 on the hypertrophic scar formation via the NF-κB signaling pathway in rabbit ears
doi: 10.1691/ph.2020.9852 (pp. 102-106)

Nari Lee, You Chul Chung, Yun Beom Kim, Sung-Min Park, Bong Seok Kim, Chang-Gu Hyun: 7,8-Dimethoxycoumarin stimulates melanogenesis via MAPKs mediated MITF upregulation
doi: 10.1691/ph.2020.9735 (pp. 107-111)

Original Articles

Ikeuchi-Takahashi Y, Ito S, Itokawa A, Ota M, Onuki Y, Hidaka S, Onishi H: Preparation and evaluation of orally disintegrating tablets containing taste masked microparticles of acetaminophen
doi: 10.1691/ph.2020.9126 (pp. 2-6)

Patlolla VGR, Holbrook WP, Gizurarson S, Kristmundsdottir Þ: Evaluation of in vitro mucoadhesiveness and texture profile analysis of doxycycline in situ hydrogels
doi: 10.1691/ph.2020.9122 (pp. 7-12)

Choi I, Park SY, Lee SW, Kang Z, Jin YS, Kim IW: Dissolution enhancement of sorafenib tosylate by co-milling with tetradecanol post-extracted using supercritical carbon dioxide
doi: 10.1691/ph.2020.9120 (pp. 13-17)

Mengying Li, Dengke Yin, Jiacheng Li, Fuping Shao, Qingqing Zhang, Qianqian Jiang, Mengmeng Zhang, Ye Yang: Rosmarinic acid, the active component of Salvia miltiorrhizae, improves gliquidone transport by regulating the expression and function of P-gp and BCRP in Caco-2 cells
doi: 10.1691/ph.2020.9754 (pp. 18-22)

Hang Jing, Guo Yi-Jia, Song Bai-Li, Lin Ya-Peng, Zhang Yu-Qiao, Geng Cong,
Hao Jun-Li, Zou Jian-Jun, Yang Jie: Effect of antiplatelet pretreatment on platelet aggregation and clinical outcomes in acute ischemic stroke patients treated with recombinant tissue-type plasminogen activator
doi: 10.1691/ph.2020.9826 (pp. 23-26)

Nguyen MTH, Ott JJ, Caputo M, Keller-Stanislawski B, Klett-Tammen CJ, Linnig S, Mentzer D, Krause G: User preferences for a mobile application to report adverse events following vaccination
doi: 10.1691/ph.2020.9734 (pp. 27-31)

Ying Xue, Meizi Zeng, Yi Zheng, Lu Wang, Song Cao, Chujun Wu, Mimi Tang, Shao Liu: Gender difference in vitamin A levels in first-episode drug-naïve depression patients: a case-control and 24-weeks follow-up study
doi: 10.1691/ph.2020.9829 (pp. 32-35)

Xiaofeng Zhang, Zhiqiang Lu, Abdul KSM, Changping Ma, Keai Sinn Tan, Jovanović A, Wen Tan: Isosteviol sodium protects heart embryonic H9c2 cells against oxidative stress by activating Akt/GSK-3β signaling pathway
doi: 10.1691/ph.2020.9851 (pp. 36-40)

Original Articles

Sutthapitaksakul L, Thanawuth K, Huanbutta K, Sriamornsak P: Effect of a superdisintegrant on disintegration of orally disintegrating tablets determined by simulated wetting test and in vitro disintegration test
doi: 10.1691/ph.2022.2015 (pp. 287-290)

Ying Xiong, Xinyue Zheng, Yongmei Xie, Youling Gong, Yi Luo: Effect of cyasterone on intestinal flora in a ^BRAFV600E-mutant mouse model of colorectal cancer
doi: 10.1691/ph.2022.2422 (pp. 291-294)

Alotaibe HF, Alolaiwi LA, Almutairi A, Alsubaie N, Badri M, Khafagy ES, Alotaibi HF: Association between levothyroxine replacement therapy and osteoporosis in Riyadh, Saudi Arabia: a matched case-control study
doi: 10.1691/ph.2022.2436 (pp. 295-298)

Ahmed NJ, Alsheri AM, Almalki ZS, Alahmari A: Drug-induced weight gain in the last 10 years: a descriptive study
doi: 10.1691/ph.2022.2408 (pp. 299-301)

Hindelang V, Dimitriadis K, Saller T, Golla K, Mannell H, Hug MJ, Strobach D: A new medication-based prediction score for postoperative delirium in surgical patients: Development and proof of feasibility in a retrospective patient cohort
doi: 10.1691/ph.2022.2438 (pp. 302-306)

Tanaka H, Okuma M, Ishii T: Occurrence of voriconazole-induced cutaneous squamous cell carcinoma in Japan: data mining from different national pharmacovigilance databases
doi: 10.1691/ph.2022.2453 (pp. 307-310)

Kohama Y, Kosugi M, Arakawa M, Hidaka S: Evaluating the impact of de-escalating antimicrobial therapy in burn patients: a retrospective cohort study
doi: 10.1691/ph.2022.2455 (pp. 311-315)

Original Articles

Guesmi H, Ben Kraim J, Alatrache A, Holzgrabe U: Hydrogen-deuterium (H/D) exchange reaction of acebutolol hydrochloride in D₂O and CD₃OD solution
doi: 10.1691/ph.2022.2419 (pp. 217-223)

Wenyi Li, Qiwei Chen, Weiwei Gao, Hui Zeng: ARID1A promotes chemosensitivity to gemcitabine I npancreatic cancer through epigenetic silencing of RRM2
doi: 10.1691/ph.2022.1881 (pp. 224-229)

Qian Zhou, Ting Chen: BI6727, a polo-like kinase 1 inhibitor, synergizes with gefitinib to suppress hepatocellular carcinoma cells via a G2/M arrest mechanism
doi: 10.1691/ph.2022.2392 (pp. 230-235)

Alavez-Pérez N, Patiño-Camacho IS, Granados-Soto V, Déciga-Campos M: Melatonin synergizes with the antinociceptive effect of N-palmitoylethanolamide and paracetamol
doi: 10.1691/ph.2022.2428 (pp. 236-242)

Yamashiro K, Hosomi K, Yokoyama S, Ogata F, Nakamura T, Kawasaki: Adverse event profiles of hypomagnesemia caused by proton pump inhibitors using the Japanese Adverse Drug Event Report (JADER) Database
doi: 10.1691/ph.2022.2416 (pp. 243-247)

Ohno H, Mano S, Katagiri N, Oguri R, Miyazaki K, Ito K, Sekiya Y, Inoue K, Masuda A, Tsuzuku A, Asano F, Hirashita T, Hayashi T: Influence of using history of immune checkpoint inhibitor therapy for neutropenia caused by combination therapy of ramucirumab and docetaxel
doi: 10.1691/ph.2022.2403 (pp. 248-254)

Uwai Y, Nabekura T: Analysis of adverse drug events in patients with bipolar disorders using the Japanese Adverse Drug Event Report database
doi: 10.1691/ph.2022.2386 (pp. 255-261)

Fujimori M, Nakamura M: Association between seasonal influenza vaccines and the increased risk of acute disseminated encephalomyelitis, estimated using the Vaccine Adverse Event Reporting System
doi: 10.1691/ph.2022.2354 (pp. 262-269)

Inić S, Gašparac P: Overview of Dioscorides’ recipes in Croatian books of folk recipes
doi: 10.1691/ph.2022.2027 (pp. 270-277)

Semedo MG, Pereira AL, Pita JR: Cinchona bark and quinine in the Portuguese official pharmacopoeias (1794-2001)
doi: 10.1691/ph.2022.2034 (pp. 278-285)

Original Articles

Kryeziu TL, Haloci E, Loshaj-Shala A, Bağci U, Oral A, Stefkov GJ, Zimmer A, Basholli-Salihu M: Nanoencapsulation of Origanum vulgare essential oil into liposomes with anticancer potential
doi: 10.1691/ph.2022.1230 (pp. 172-178)

Hehe Cui, Yuejin Yang, Xiangdong Li, Wenjing Zong, Qing Li: Resveratrol regulates paracrine function of cardiac microvascular endothelial cells under hypoxia/reoxygenation condition
doi: 10.1691/ph.2022.2370 (pp. 179-185)

So Yeon Kim, Yung-Yoon Kim, In Wook Kim, Hye-Young Yun, Dong-Seok Kim: LGl3 promotes human keratinocyte migration in high-glucose environments by increasing the expression of β-catenin
doi: 10.1691/ph.2022.2359 (pp. 186-190)

Ortíz-Rodríguez MA, Oaxaca-Navarro J, Patiño-Camacho SI, García-Jiménez S, Déciga-Campos M, Martínez-Salazar MF: Plasma levels of efavirenz and frequency of the CYP2B6 516G>T polymorphism in people living with HIV-1 in Mexico
doi: 10.1691/ph.2022.2382 (pp. 191-195)

Saito Y, Takekuma Y, Komatsu Y, Sugawara M: Evaluation of risk factors for chemotherapy-induced nausea and vomiting in cisplatin and gemcitabine treatment for biliary tract cancer: acid suppressants do not prevent nausea
doi: 10.1691/ph.2022.2355 (pp. 196-201)

Ichimura T, Ogawa C, Murata H, Miyahara K, Yuge S, Tsukioka R, Kado K, Yoshimura T, Suzuki K, Nomura H, Shimizu H: Community pharmacists’ measurement of health-related quality of life in outpatients taking high-risk drugs
doi: 10.1691/ph.2022.1914 (pp. 202-206)

Schilling S, Koeck JA, Kontny U, Orlikowsky T, Erdmann H, Eisert A: High-alert medications for hospitalised paediatric patients – a two-step survey among paediatric clinical expert pharmacists in Germany
doi: 10.1691/ph.2022.12025 (pp. 207-215)

Original Articles

Ushijima H, Onoder A: Selective growth suppressive effect of pravastatin on senescent human lung fibroblasts
doi: 10.1691/ph.2022.2327 (pp. 132-136)

Weiwei Zhou, Weizhe Liu, Dinyan Zhou, Aiying Li: ITGB1 suppresses autophagy through inhibiting the mTORC2/AKT signaling pathway in H9C2 cells doi: 10.1691/ph.2022.2351(pp. 137-140)

Hongxin Sun, Yumiko Urakami-Takebayashi, Hideyuki Motohashi, Junya Nagai: Internalization of FITC-albumin in human adipose-derived stem cells: Involvement of clathrin and caveolin
doi: 10.1691/ph.2022.2340 (pp. 141-146)

Yi-Lun Wang, Jin-Jie Yang, Wan Ni: Immunomodulatory effects of sinensetin on macrophage and cyclophosphamide-induced immunosuppression in mice
doi: 10.1691/ph.2022.2321 (pp. 147-151)

Hyunmin Ko, Young Il Kim, Hyung Joon Ahn: Activin suppresses the inflammatory response of TNF-α-stimulated human umbilical vein endothelial cells
doi: 10.1691/ph.2022.2330 (pp. 152-156)

Obayashi K, Nagamine A, Yashima H, Ohshima S, Uchiyama C, Takahashi E, Takahashi Y, Araki T, Yamamoto K: Comparison of the antiemetic effect of aprepitant/granisetron and palonosetron combined with dexamethasone in gynecological cancer patients treated with paclitaxel and carboplatin combination regimen
doi: 10.1691/ph.2022.12000 (pp. 157-161)

Fukuoka T, Yamamoto Y, Usami E, Hayashi H, Utsunomiya J, Kimura M, Nakamura M, Yoshimura T, Toda Y: Expression of peripheral neuropathy after vincristine treatment related to different administration methods
doi: 10.1691/ph.2022.2329 (pp. 162-164)

Kose E, Endo H, Hori H, Hosono S, Kawamura C, Kodama Y, Yamazaki T, Yasuno N: Association of pharmacist-led deprescribing intervention with the functional recovery in convalescent setting
doi: 10.1691/ph.2022.2323 (pp. 165-170)

Original Articles

Hossain M, Hall SC, Wiggington PJ, Roth SM, Das S, Das U, Roayapalley PK, Dimmock JR:  Cytotoic benzylidene hydrazides of terephthalic acid and related compounds
doi: 10.1691/ph.2022.11072 (pp. 90-94)

Al Azzam KM: A novel and simple dynamic coating capillary electrophoresis method for the chiral separation and quantification of mitiglinide entantiomers using hydroxyethyl cellulose as a dynamic coating agent
doi: 10.1691/ph.2022.1166 (pp. 95-102)

Miyazaki Y, Uchino T, Kagawa Y: Effect of batchsize on the granule properties in planetary centrifugal granulation
doi: 10.1691/ph.2022.11059 (pp. 103-106)

Huanbutta K, Thanawuth K, Sutthapitaksakul L, Ririyaprasarth S, Cheewatanakornkool K, Maksup S, Theeratanapartkul K, Sathorn P, Phusamlee P, Kwanjaiphanich T, Sangnim T, Sriamornsak P: Development and optimization of Clinacanthus nutans liquid spray using a two-level full factorial design
doi: 10.1691/ph.2022.1236 (pp. 109-112)

Yiwei Hu, Huiting Qu, Jie He, Hongyao Zhong, Shoukai He, Peng Zhao, Leyao Zhang, Jinghua Chen, Chao Deng: Human placental mesenchymal stem cell derived exosomes exhibit anti-inflammatory effects via TLR4-mediated NF-κB/MAPK and Pl3K signaling pathways
doi: 10.1691/ph.2022.11082 (pp. 113-118)

Nagai K, Fukuno S, Moriwaki R, Kuroda H, Omotani S, Miura T, Hatsuda Y, Myotoku M, Konishi H: Influene of concurrent and staggered dosing of semi-solid nutrients on the pharmacokinetics of orally administered carbamazepine in rats
doi: 10.1691/ph.2022.1756 (pp. 119-121)

Qiong Wang, Shenghan Gao, Wensheng Zhang, Yunxia Zhao, Yi He, Wei Sun, Fenglian Zhang, Tong Yu, Lihong Zhou, Zhengliang Ye, Jiansen Su, Shunnan Zhang, Yongfa Chen: Traditional use and safety evaluation of combination Traditional Chinese Medicine in European registration: with XiaoYao tablets as an example
doi: 10.1691/ph.2022.1227 (pp. 126-131)

Original Articles

Yang L, Higashisaka K, Haga Y, Tsujino H, Nagano K, Tsutsumi Y: Alpha-cystallin B chains enhance cell migration in basal-like 2 triple-negative breast cancer cells
doi: 10.1691/ph.2022.11019 (pp. 45-47)

Jian Tang, Zhenlong Zhou, Jun Qian, Xiaoling Lin, Qiwei Liu, Qiuling Xie, Sheng Xiong: KdPT alleviates imiquimod-induced psoriasis-like skin lesion in mice via inhibiting proliferation and inflammation resoponse
doi: 10.1691/ph.2022.1970 (pp. 48-53)

Kato R, Ijiri Y: Regorafenib and reactive metabolite of sunitinib activate inflammasomes: Implications for multi tyrosine kinase inhibitor-liduced immune related adverse events
doi: 10.1691/ph.2022.1955 (pp. 54-58)

Jianhua Li, Huanxian Wu, Shidong Lv, Dongling Quan, Danni Yang, Jiahuan Xu, Boyu Chen, Baofang Ou, Shaoyu Wu, Qiang Wei: Enhanced antitumor efficacy by combining afatinib with MDV3100 in castration-resistant prostate cancer
doi: 10.1691/ph.2022.1948 (pp. 59-66)

Bosch KE, Werner CJ, Rueckbeil MV, Eisert A: Use of electronic adverse drug reaction check to identify inpatients with a high drug-associated risk of falling: a case-control study at the Department of Neurology
doi: 10.1691/ph.2022.1807 (pp. 67-75)

Takikawa M, Tanaka H, Obara T, Maeda Y, Sato M, Shimazaki Y, Mori Y, Ishigami A, Ishii T: Utility of the Berlin Initiative Study-1 equation for the prediction of serum vancomycin concentration in elderly patients aged 75 years and older
doi: 10.1691/ph.2022.1972 (pp. 76-80)

Morii Y, Fujimoto S, Nakahara R, Okawa K, Senaha H, Fujiwara K, Tsubaki M, Matzno S, Takegami M, Shimomura K, Nishida S: Effect of proton pump inhibitors on the development of hypomagnesemia induced by panitumumab
doi: 10.1691/ph.2022.1988 (pp. 81-84)

Sugisaki T, Aoyama T, Kawakami K, Yokokawa T, Kobayashi K, Suzuki W, Ogura M, Ichimura T, Chin K, Yamaguchi K, Hanaoka S, Hayashi H, Yamaguchi M: Correlation between magnesium pre-loading and cisplatin-induced nephrotoxicity in
5­­-fluorouracil/cisplatin combination therapy for espohageal cancer
doi: 10.1691/ph.2022.11038 (pp. 85-88)

Original Articles

Sehner SM, Melzig MF: Fluorometric quantification of alkaloids in the homeopathic mother tinctures of Vinca minor L. and Fumaria officinalis L.
doi: 10.1691/ph.2022.1135 (pp. 2-5)

Miura M, Tanaka S, Ikedoa M, Kawakami J, Watanabe H, Namiki N, Uchida S: Increased plasma drug concentration and decreased additional insulin secretion following oral administration of glimepiride in Spontaneously Diabetic Torii rats
doi: 10.1691/ph.2022.1950 (pp. 6-8)

Hyun Sik Kang, Jin Yong Song, Jong Heon Kim, Tae Il Park, Won Seok Choi, Ji-Yun Lee: Effects of vinpocetine on atopic dermatitis after administration via three different routes in HR-1 hairless mice
doi: 10.1691/ph.2022.1941 (pp. 9-13)

Lixia Qiang, Zhiheng Li, Gongchen Wang, Xiangshun Li, Meiyu Lv, Baocai Wang, Zhaoquan Shi, Shoude Jin: Anti-TIM1 suppresses airway inflammation and hyperresponsiveness via the STAT6/STAT1 pathways in mice with allergic asthma
doi: 10.1691/ph.2022.1670 (pp. 14-20)

Yuankai Si, Zhigui Wu, Li Gu, Hua Li, Pei Ge, Wenxian Yin, Meijuan Chen: Changes of BKCA current and vascular reactivity in vascular smooth muscle of thoracic aorta and mesenteric artery in type 2 diabetic rats
doi: 10.1691/ph.2022.1740 (pp. 21-26)

Zupanets IA, Shebeko SK, Popov SB, Zupanets KO, Zimin SM: Analgesic properties of the dry combined extract BNO 1016 in leukotriene depended hyperalgesia
doi: 10.1691/ph.2022.0505 (pp. 27-31)

Xiao Yang, Shiyue Lang, Shuqi Li, Chunlai Jiang, Jiahong Han: Preparation of icariside l and icariside ll, an exploration of their protective mechanism against cyclophosphamide-induced bone marrow suppression in mice, and their regulatory effects on immune function
doi: 10.1691/ph.2022.1771 (pp. 32-37)

Seiberth S, Berner J, Hug MJ, Strobach D: `Double Whammy`and `Triple Whammy`combinations in hospitalized surgical patients – real life data from a tertiary teaching hospital
doi: 10.1691/ph.2022.1913 (pp. 38-43)

Review

Yang Su, Fan Zhang, Wen Qin, Lun Wu, Qiuhong Wang, Genhong Cheng, Haixue Kuang: “Gut-skin”axis: understanding psoriasis from the gut
doi: 10.1691/ph.2021.1694 (pp. 523-527)

Original Articles

 Pajaziti B, András M, Nebija D, Anastova L, Petkovska R: Chemometrics approach for optimization of capillary electrophoretic conditions for the separation of insulin analogues
doi: 10.1691/ph.2021.1758 (pp. 528-531)

Sobczyński J, Chudzik-Rząd B: The in vitro photocytotoxicity of photosensitizer encapsulated by nanovehicles comprising biomimetic phospholipids
doi: 10.1691/ph.2021.0047 (pp. 523-537)

Zhengqin Dong, Qianqian Feng, Han Zhang, Qiang Liu, Jianhua Gong: Curcumin enhances drug sensitivity of gemcitabine-resistant lung cancer cells and inhibits metastasis
doi: 10.1691/ph.2021.0927 (pp. 538-543)

Mengru Lu, Junli Liang, Jinyu Liang, Hepeng Li, Peng Yang: The effects of the renin inhibitor aliskiren on neuronal toxic damage
doi: 10.1691/ph.2021.1729 (pp. 544-550)

Jiangchao Zhuang, Xie Zhou, Ting Liu, Shuai Zhang, Falei Yuan, Leifang Zhang, Zuisu Yang, Yan Chen: Astaxanthin attenuated hyperuricemia and kidney inflammation by inhibiting uric acid synthesis and the NF-κB/NLRP3 signaling pathways in potassium oxonate and hypoxanthine-induced hyperuricemia mice
doi: 10.1691/ph.2021.1731 (pp. 551-558)

Lianlian Yang, Mingyan Jiang, Ruixin Yu, Ruolan Hu, Fei Xiong, Jinrong Li: A case report of precocious puberty related to Rett syndrome and a literature review
doi: 10.1691/ph.2021.1747 (pp. 559-561)

Strobach D, Schlattl A, Schieck S, Bertsche T: QTc-time-prolongating drugs and additional risk factors for long-QT-syndrome at hospital admission of surgical patients – risk assessment by pharmacists
doi: 10.1691/ph.2021.1697 (pp. 562-566)

Reviews

Abushammalla I: Tacrolimus and herbs interactions: a review
doi: 10.1691/ph.2021.1684 (pp. 468-472)

Yang Su, Jing Li, Lun Wu, Haixue Kuang: Polysaccharides from TCM herbs exhibit potent anti-obesity effect by mediating the community structure of gut microbiota
doi: 10.1691/ph.2021.1463 (pp. 473-479)

Original Articles

Ghasemisarabbadieh M, Sigurdsson SJ, Nu Dong FV, Gizurarson S, Sveinbjörnsson BR: The effect of D-(+)-glucosamine, N-acetyl-D-glucosamie and tetraethylene glycol on the stability of oxytocin in aqueous solution
doi: 10.1691/ph.2021.1081 (pp. 480-483)

Sekiguchi M, Sagano N, Kawazoe H, Hiraga Y, Jibiki A, Yokoyama Y, Suzuki S, Nakamura T: Drug repositioning of antipsychotic drugs for cisplatin-induced pica behavior in mice
doi: 10.1691/ph.2021.1674 (pp. 484-487)

Qi Li, Zhuqing Li, Tingting Li, Yanxin Wang, Jiaxin Feng, Chengzhi Lu: Efficacy and safety of soluble guanylate cyclase stimulators in patients with heart failure: A systematic review and meta-analysis
doi: 10.1691/ph.2021.1599 (pp. 488-493)

Xuemin Li, Long Yang, Shasha Zhang, Jie Shen: The molecular mechanism of the transcriptional activator SWI regulating gene ARID1B affecting swallowing dysfunction after stroke in rats
doi: 10.1691/ph.2021.1602 (pp. 494-498)

Lijun Tao, Lina Chen, Yanmin Pei, Ping Ma, Qinbin Xu, Jialing Wang, Yang Yu, Jiang Cheng, Ru Zhou: Vasodilatory effects of betaine on isolated rat pulmonary artery rings
doi: 10.1691/ph.2021.1392 (pp. 499-502)

Liuliu Pan, Xiaodan Zhang, Danhan Wang, Min Huang, Qiusui Huang, Ping Duan, Jie Mei: DCLK1 might be a therapeutic target of osthole against cervical cancer
doi: 10.1691/ph.2021.1641 (pp. 503-506)

Jing-Jing Yu, Fei Wu, Rui-Rui Ma, Tian-Jin Wu, Yuan Zhang, Zhen-Hua Ying: The effects of iguratimod combined with methotrexate and hydroxychloroquine on bone mineral density in patients with rheumatoid arthritis
doi: 10.1691/ph.2021.1630 (pp. 507-510)

Lin Zheng, Jiamin Du, Fujing Ge, Meijia Qian, Bo Yang, Qiaojun He, Qinjie Weng, Hong Zhu: The calcimimetic agent cinacalcet inhibits hepatocellular carcinoma via YAP/TAZ suppression
doi: 10.1691/ph.2021.1646 (pp. 511-514)

Ohyama K, Hirakawa K, Sasazaki K, Tanaka H, Hori Y, Takeuchi H: Time-to-onset of diabetes with everolimus use: analysis of a spontaneous reporting system database
doi: 10.1691/ph.2021.1624 (pp. 515-518)

Bach-Rojecky L, Lackovic Z: A century of phage therapy: from novel discoveries about the past to the challenges of the today
doi: 10.1691/ph.2021.1114 (pp. 519-521)

Review

Yangni Li, Yishu Zhang, Xuran Li, Yanfen Huang, Weiyan Chen, Lan He, Yuyan Zhang: Status of hypoxia-inducible factor-1α expression in non-small cell lung cancer
doi: 10.1691/ph.2021.1524 (pp. 404-411)

Original Articles

 Xuan GS, Zhan JH, Zhang AM, Li W, Zheng K: Inhibition of carbonic anhydrase ll by sulfonamide derivatives
doi: 10.1691/ph.2021.1590 (pp. 412-415)

Baba S, Yumoto R, Kawami M, Takano M: Functional expression of equilibrative and concentrative nucleoside transporters in alveolar epithelial cells
doi: 10.1691/ph.2021.1017 (pp. 416-421)

Yujiao He, Xiao Liu, Maolin Huang, Zheng Wei, Mengyu Zhang, Mengtao He, Zhebin Zheng, Hongbo Dong, Deming Liu: Oleanolic acid inhibits the migration and invasion of hepatocellular carcinoma cells by promoting microRNA-122 expression
doi: 10.1691/ph.2021.1366 (pp. 422-427)

Lulu Cao, Xiojia Lou, Lili Zhou, Yuedan Wu: The decrease of T3 / T4 is not hypothyroidism – a new mutation of Serpina7 gene results in partial thyroglobulin deficiency
doi: 10.1691/ph.2021.1559 (pp. 428-430)

Ning Cai, Qing Yang, Dao-Biao Che, Xin Jin: 20(S)-Ginsenoside Rg3 regulates the Hedgehog signaling pathway to inhibit proliferation and epithelial-mesenchymal transition of lung cancer cells
doi: 10.1691/ph.2021.1573 (pp. 431-436)

Fujimori M, Hasegawa S, Sasaoka S. Iguchi K, Nakamura M: A study of the association between seasonal influenza vaccines and the increased risk of Guillain-Barré syndrome using Vaccine Adverse Event Reporting System, 2018-2019
doi: 10.1691/ph.2021.1578 (pp. 437-443)

Yasuda M, Tachi T, Osawa T, Watanabe H, Inoue S, Makino T, Nagaya K, Morita M, Tanaka K, Aoyama S, Kasahara S, Teramachi H, Mizui T: Risk factors for thrombocytopenia and analysis of time to platelet transfusion after azacytidine treatment
doi: 10.1691/ph.2021.1566 (pp. 444-449)

Ichimura T, Nomura H, Shimizu H, Machida Y, Suzuki K: Cost-effectiveness of primary prophylaxis of febrile neutropenia with pegfilgrastim in docetaxel, cisplatin and 5-fluorouracil therapy for esophageal cancer
doi: 10.1691/ph.2021.1031 (pp. 450-454)

Wilhelmy S, Bekel AI, Gross D, Schmidt M: Forced to join the Waffen-SS? Chief pharmacist Victor Capesius (1907-1985) and his role in Auschwitz concentration camp
doi: 10.1691/ph.2021.1070 (pp. 455-460)

Petroianu GA, Lorke DE: Vinum resinatum: Scientists and unintended consequences
doi: 10.1691/ph.2021.1080 (pp. 461-466)

Reviews

Noe CR, Noe-Letschnig M: The role of ACE2 in the renin-angiotensin-system: Etiology and therapy of COVID-19 from a pharmaceutical perspective
doi: 10.1691/ph.2021.1618 (pp. 342-350)

Qun Feng, Zhiyan Huang, Ying Sun, Rong Sun, Guimin Zhang: Stilbene glucoside: recent advances in pharmacology, bioinformatics investigation, toxicity and future opportunities
doi: 10.1691/ph.2021.1393 (pp. 351-358)

Yining Zhao, Shuangmei Liu: Bioactivity of naringin and related mechanisms
doi: 10.1691/ph.2021.1504 (pp. 359-363)

Original Articles

Bao-Xin Li, Juan Lv, Xin Zhang, Can Zhang, Shu-Qin Guo, Rui-Jiang Ma, He Wang, Yun-Liang Zhang: Hypoglycemic effect of insulin-loaded hydrogel-nanogel composite on streptozotocin-induced diabetic rats
doi: 10.1691/ph.2021.1344 (pp. 364-371)

Shu-Yan Zhou, Xin-Yi Chen, Yan Chen, Na-Na Meng, Xin Tao, Hua-Long He, Zhi-Hao Liu, Ning-Yu Wang, Luo-Ting Yu: A novel fixed-dose combination treatment for chronic hepatitis C, based on NS5A inhibitor fopitasvir and NS5B inhibitor sofosbuvir
doi: 10.1691/ph.2021.0190 (pp. 372-378)

Zhenbin Li, Xuan Chen, Xiangjun Yi: The effects of A549 and H1299 cell-derived exosomes on the proliferation and apoptosis of BEAS-2B cells
doi: 10.1691/ph.2021.1513 (pp. 379-387)

Yuxin Chen, Yanqing Wu: Reverse remodeling in a heart failure patient with cardiomegaly treated with sacubitril/valsartan: a case report
doi: 10.1691/ph.2021.1546 (pp. 388-389)

Samardžić I, Marinović I, Kuča N, Bačić Vrca V: Potential clinically significant drug-drug interactions in prescribed pharmacotherapy in an outpatient setting
doi: 10.1691/ph.2021.1561 (pp. 390-395)

Semedo MG, Pereira AL, Pita JR: The influence of German science on Clinchona and quinine research in Portugal in the second half of the 19^th
doi: 10.1691/ph.2021.1050 (pp. 396-402)

Original Articles

Tae Kon Kim: Determination of SK7324, a new class of hepatitis C virus inhibitor, in rat plasma by UPLC-MS/MS and its application to the pharmacokinetic study of SK7324
doi: 10.1691/ph.2021.1442 (pp. 295-299)

Muhana F, Al-Ani I, Al-Akayleh F, Marzouqa D, Khalili F, Al-Khatib H, Mutti H, Shalan N: Synthesis and characterization of mesoporous silica and its application as drug delivery system for glimepiride
doi: 10.1691/ph.2021.1309 (pp. 300-307)

Zhou H, Xu P, Sun Y: Pharmacokinetics of abiraterone acetate released from a tablet based
on lipid matrix in beagle dogs
doi: 10.1691/ph.2021.0171 (pp. 308-312)

Kapelka I, Shtrygol S, Koiro O, Merzlikin S, Kudina O, Yudkevych T: Effect of arachidonic acid cascade inhibitors on body temperature and cognitive functions in rats in the Morris water maze after acute cold injury
doi: 10.1691/ph.2021.1571 (pp. 313-316)

Koeck JA, Mastragelopoulos N, Just KS, Eisert A: The prevalence of ‘triple whammy’ prescriptions in surgical inpatients and associated pharmacist recommendations
doi: 10.1691/ph.2021.1323 (pp. 317-327)

Kimura M, Usami E, Teramachi H, Yoshimura T: Identifying prognostic factors associated with overall survival in second-line paclitaxel plus ramucirumab treated human epidermal growth factor receptor 2-negative advanced/recurrent gastric cancer
doi: 10.1691/ph.2021.1432 (pp. 328-333)

Mori K, Yoshida M, Tomita K, Nakamura M, Yoshimura T: Intervention of dementia support team pharmacists and its effects for the proper use of rivastigmine
doi: 10.1691/ph.2021.1534 (pp. 334-337)

Ye Yang, Junjie Li, Ping Yu, Jun Ge, Bin Liu, Juan Li: A case of the third-line treatment of lung adenocarcinoma using nivolumab combined with anlotinib
doi: 10.1691/ph.2021.1420 (pp. 338-340)

Original Articles

Feng Bian, Yufeng Zhang, Yuanlong Xie, Hongyu Fang, Mingyu Fan, Xin Wang, Hongliang Li, Tao Huang, Sheng Zhang, Lin Cai: Effects of different concentrations of metformin on osteoclast differentiation and apoptosis and its mechanism
doi: 10.1691/ph.2021.1378 (pp. 244-248)

Fenxia Li, Kangli Zhang, Meng Yu, Tongtong Chen, Liyan Ma, Hongwu Zhang, Hongmei Jia, Zhongmei Zou: Antidepressant-like effect and phytochemical profile of supercritical CO2 extract from Citri reticulatae pericarpium
doi: 10.1691/ph.2021.1408 (pp. 249-255)

Lu Yuyu, Zhang Shikun, Zhang Zhenyu, Jiang Zongdan, Sun Weihao: MiR-877-5p targets PDK-1 to promote aspirin-induced apoptosis in gastric mucosal cells
doi: 10.1691/ph.2021.0926 (pp. 256-260)

Shimanuki Y, Hashimoto H, Kawazoe H, Uozumi R, Udagawa R, Watabe D, Nakamura T, Yamaguchi M,
Terakado H: Preventive effects of self-administered cryotherapy on paclitaxel-induced peripheral neuropathy in patients with early-stage breast cancer: a propensity score analysis
doi: 10.1691/ph.2021.1398 (pp. 261-265)

Arami T, Kawazoe H, Uozumi R, Hashimoto H, Egami S, Sakiyama N, Ohe Y, Nakada H, Aomori T, Ikemura S, Yasuda H, Kawada I, Fukunaga K, Soejima K, Yamaguchi M, Nakamura T: Effect of renin-angiotensin system inhibitors on pemetrexed plus platinum-induced hematological toxicities: a multicenter retrospective study using three propensity score analyses
doi: 10.1691/ph.2021.1409 (pp. 266-271)

Grgurević D, Grugurević J, Bačić Vrca V, Marušić S, Marinović I, Barić Grugurević A: Incidence of potential drug interactions in co-prescription of statins and macrolide antibiotics in Croatia during the 14 year period
doi: 10.1691/ph.2021.1412 (pp. 272-278)

Matsuyama T, Tachi T, Katsuno H, Sugioka M, Aoyama S, Osawa T, Koyama A, Murayama A, Noguchi Y,
Yasuda M, Mizui T, Goto C, Teramachi H: Effects of polypharmacy on the prevalence of adverse drug events resulting in outpatient visits and hospitalization
doi: 10.1691/ph.2021.1427 (pp. 279-286)

Pietryjia M, Kurkiewicz S, Kurkiewicz M, Błońska-Fajfrowska B:
Hermit Treutler’s Jerusalem Balsam
doi: 10.1691/ph.2021.1024 (pp. 287-293)

Original Articles

Hong Qiang, Jianbo Li, Shuaishuai Wang, Tiange Feng, Huijie Cai, Zhilei Liu, Jingjing Yuan, Wanli Zhang, Jinjie Zhang, Zhenzhong Zhang: Distribution of systemically administered nanoparticles during acute pancreatitis: effects of particle size and disease severity
doi: 10.1691/ph.2021.0156 (pp. 180-188)

Huang F, Marzin K, Koenen R, Kammerer KP, Strelkowa N, Elgadi M, Haertter S: Effect of itraconazole on the pharmacokinetics of faldaprevir in healthy subjects
doi: 10.1691/ph.2021.0197 (pp. 189-194)

Tianming Dai, Min Wang, Pengzhen Wang, Libing Dai, Renke Dai, Qingqi Meng: Inhibition effects of eight anti-coronavirus drugs on glycosides metabolism and glycosidases in human gut microflora
doi: 10.1691/ph.2021.01005 (pp. 195-201)

Xueshan Wen, Xing Zhang, Shulan Qu, Xugang Chen, Cheng Liu, Yifu Yang: Coptisine induces G2/M arrest in esophageal cancer cell via the inhibition of p38/ERK1/2/claudin-2 signaling pathway
doi: 10.1691/ph.2021.1353 (pp. 207-207)

Yu-Ye Xue, Yun-Yang Lu, Guang-Qiang Sun, Fei Fang, Yu-Qiang Ji, Hai-Feng Tang, Peng-Cheng Qiu, Guang Cheng: CN-3 induces mitochondrial apoptosis in glioma via Ros-mediated Pl3KAKT pathway
doi: 10.1691/ph.2021.1363 (pp. 208-214)

Caihong Hu, Zhengbo Liang, Ping Lai, Xiaofang Wang, Changming Zhao: Efficacy of atezolizumab to treat non-small-cell lung cancer: a meta-analysis based on randomized clinical trials
doi: 10.1691/ph.2021.1336 (pp. 215-219)

Shu Zhang, Xianzhi Xu, Yuanhong Huang, Siyuan Sun, Chengqi Jin, Hao Ji, Dong Sun, Anzhou Xia: Anisodamine ameliorates ischemia/reperfusion-induced renal injury in rats through activation of the extracellular signal-regulated kinase (ERK) pathway and anti-apoptotic effect
doi: 10.1691/ph.2021.1302 (pp. 220-224)

Chi-Ming Liu, Zhengping Wu, Bo Pan, Lijie An, Conglei Zhu, Jiqin Zhou, Yinjie Jiang: The antiandrogenic effect of neferine, liensinine, and isoliensinine by inhibiting 5-α-reductase and androgen receptor expression via Pl3K/AKT signaling pathway in prostate cancer
doi: 10.1691/ph.2021.1301 (pp. 225-231)

Bo Cui, Zhe Yang, Shuning Wang, Mengnan Guo, Qianqian Li, Qiuhua Zhang, Xiuli Bi: The protective role of protocatechuic acid against chemically induced liver fibrosis in vitro and in vivo
doi: 10.1691/ph.2021.0909 (pp. 232-238)

Fukuoka T, Yamamoto Y, Utsunomiya J, Usami E, Kimura M, Yoshimura T, Nakamura M, Tody Y: Association between immune-related dermatologic adverse events and efficacy of pembrolizumab in non-small cell lung cancer patients
doi: 10.1691/ph.2021.01018 (pp. 239-242)

Review

Bing Chen, Yishu Zhang, Simiao Chen, Xuran Li, Jingyi Dong, Weiyan Chen, Shuiliang Tao, Weiji Yang, Yuyan Zhang: The role of vascular endothelial growth factor in ischemic stroke
doi: 10.1691/ph.2021.1315 (pp. 127-131)

Original Articles

Haiping Yao, Yanyan Wang, Jiangwen Mo, Yan Peng, Zhu Wang: Design, synthesis, and biological evaluation of isoquinolin 1-(2H)-one derivates as tankyrase-1/2 inhibitors
doi: 10.1691/ph.2021.0904 (pp. 132-137)

Farias FF, Martins VAP, Dörr FA, Trujillo LM, Pinto E: Forced degradation study and characterization of main impurities of ibuprofen soft gelatin capsules by LC-MS-QTOF
doi: 10.1691/ph.2021.0126 (pp. 138-144)

Shuai Liu, Junfeng Zhu, Chang Liu, Jiazeng Li, Li Zhang, Jian Zhao, Hongsheng Liu: Synthesis of sustained release/controlled release nanoparticles carrying nattokinase and their application in thrombolysis
doi: 10.1691/ph.2021.0155 (pp. 145-149)

Mékidèche T, Curti C, Lamy E, Jean C, Bertault Peres P, Vanelle P: Compounding and quality control of two pediatric topiramate pharmaceutical preparations
doi: 10.1691/ph.2021.0176 (pp. 150-154)

Albassam AA, Ahad A, Alsultan A, Yusufoglu HS, Foudah AI, Al-Jenoobi FI: The inhibition of CYP1A2, CYP2C9, and CYP2D6 by pterostilbene in human liver microsomes
doi: 10.1691/ph.2021.1304 (pp. 155-158)

Juncheng He, Qifeng Zhou, Xianchao Jia, Peng Zhou, Lin Chen: Immune-related expression profiles of bisphosphonates-related osteonecrosis of the jaw in multiple myeloma
doi: 10.1691/ph.2021.01013 (pp. 159-164)

Zhujun Yin, Ruirong Tan, Tianmin Yuan, Shilong Chen, Yunyun Quan, Qing Hao, Jin Zeng, Junning Zhao, Li Li: Berberine prevents diabetic retinopathy through inhibiting HIF-1α/VEGF/NF-κB pathway in db/db mice
doi: 10.1691/ph.2021.0933 (pp. 165-171)

Yifan Chen, Min Zhang, Xinghao Ji, Jinjin Zhao, Shuang Qin, Yinghua Ji, Ruijuan Fan, Yanting Liu, Ping Lu: The anti-cancer effect of metoclopramide on triple-negative breast cancer cells
doi: 10.1691/ph.2021.0977 (pp. 172-174)

Kanabayashi Y, Amaya F, Ueno H, Tabuchi Y, Ishikawa T, Takayama K, Taguchi T: Factors affecting the effect of naldemedine for opioid-induced constipation: a single-institution, retrospective analysis
doi: 10.1691/ph.2021.0959 (pp. 175-178)

Reviews

Kumar SA, Weyland Cheng: A hypothesis: Bitter taste receptors as a therapeutic target for the clinical symptoms of SARS-CoV 2
doi: 10.1691/ph.2021.0840 (pp. 43-54)

Xin-xin Zhang, Dong-sheng Zhao, Jie Wang, Hui Zhou, Lei Wang, Jin-long Mao,
Ji-xiang He: The treatment of cardiovascular diseases: a review of ferulic acid and its derivatives
doi: 10.1691/ph.2021.0958 (pp. 55-60)

Xiao-Ming Xi, Chen-Meng, Shu-Jun Xia, Rong Liu: Drug loading techniques for
exosome-based drug delivery systems
doi: 10.1691/ph.2021.0128 (pp. 61-67)

Original Articles

Tavares HS, Cardoso JF, Almeida TC, Marques MBF, Mussel WN, Lopes MCP,
Oréfice RL, Andrade SN, Varotti FP, Silva GN, da Silva GR: Spiramyin-loaded PLGA implants for the treatment of ocular toxoplasmosis: development, characterization, biocompatibility, and anti-toxoplasma activity
doi: 10.1691/ph.2021.0100 (pp. 68-76)

Witika BA, Walker RB: Preformulation characterization and identification of excipients for nevirapine loaded niosomes
doi: 10.1691/ph.2021.0137 (pp. 77-83)

Tian Deng, Na Zhang, Yi Liu, Junmin Li: Daidzein ameliorates experimental acute reflux esophagitis in rats via regulation of cytokines
doi: 10.1691/ph.2021.01003 (pp. 84-91)

Shengli Li, Likun Sun, Qian Zhou, Shuo Li, Xiaoli Liu, Juan Xiao, Yaqi Xu, Fang Wang, Yang Jiang, Chengyun Zheng: Therapeutic effect and mechanism of ibrutinib combined with dexamethasone on multiple myeloma
doi: 10.1691/ph.2021.0917 (pp. 92-96)

Yan Hou, Yingli Zhen, Qingliang Xue, Wei Wang: Astragaloside lV attenuates
TGF-β-mediated epithelial-mesenchymal transition of pulmonary fibrosis via suppressing NLRP3 expression in vitro
doi: 10.1691/ph.2021.0933 (pp. 97-102)

Zhuoheng Lu, Shengtao Li, Jia Luo, Yishuang Luo, Manyun Dai, Xiuting Zheng, Jiapeng Qiu, Julin Yang, Aiming Liu: Fenofibrate reverses liver fibrosis in cholestatic mice induced by alpha-naphthylisothiocyanate
doi: 10.1691/ph.2021.0988 (pp. 103-108)

Renzhong Hu, Yijia Guo, Yapeng Lin, Yifang Tang, Qin Tang, Xiaoqing Wang, Jie Yang, Xia Wang: Safety and efficacy of edaravone combined with alteplase for patients with acute ischemic stroke: A systematic review and meta-analysis
doi: 10.1691/ph.2021.0949 (pp. 109-113)

Higashi T, Tsukamoto H, Kodawara T, Igarashi T, Watanabe K, Yano R, Iwasaki H,
Goto N: Evaluation of risk factors for nephrotoxicity associated with high-dose vancomycin
in Japanese patients
doi: 10.1691/ph.2021.0138 (pp. 114-118)

Inić S, Flegar V: Adolf Thierry and the first pharmaceutical factory in Southeast Europe
doi: 10.1691/ph.2021.0140 (pp. 119-125)

Original Articles

Kashiwagura Y, Uchida S, Hakamata A, Watanabe H, Namiki N: In vitro transdermal permeation and in vivo transdermal absorption of domperidone cream formulations compounded from tablets as a hospital formulation
doi: 10.1691/ph.2021.0082 (pp. 2-5)

Samardzic I, Marinovic I, Matkovic I, Mamic I, Bacic Vrca V: Antimicrobial drugs involved in potential drug-drug-interactions in cardiosurgical patients
doi: 10.1691/ph.2021.0774 (pp. 6-11)

Sze-Wan Wong E, Jingjing Li, Renkai Li R, Pak-Heng Leung G, Kwok-Fu Ng J: Involvement of different α₂ adrenoceptor subtypes in effects of dexmedetomidine on porcine coronary artery
doi: 10.1691/ph.2021.0878 (pp. 12-17)

Bing Hua, Hehe Cui, Qingbo Liu, Weiping Li, Hui Chen, Hongwei Li: Nicorandil protects cardiac microvascular endothelial cells from advanced glycation end products induced cytotoxicity via promoting autophagy
doi: 10.1691/ph.2021.0831 (pp. 18-22)

Ze Guo, Jinping Gao, Xing Fan, Anping Zhang, Zaixing Wang, Xianfa Tang, Yue Chen, Huayang Tang, Hui Li: Carbamazepine-induced DiHS/DRESS syndrome leading to hemophagocytic lymphohistiocytosis in a woman carrying the HLA-B*1301 gene
doi: 10.1691/ph.2021.0808 (pp. 23-26)

Yulin Wang, Run Cheng, Xinyi Wu, Mingxing Miao: Neuroprotective and neurotrophic effects of ginkgetin and bilobalide on MPTP-induced mice with Parkinson’ disease
doi: 10.1691/ph.2021.0799 (pp. 27-33)

Feng Xiao, Shi-Ming Zhang, Yan-Ping Wang: MiR-301a is interrelated with poor prognosis and contributes to temozolomide resistance in human glioma
doi: 10.1691/ph.2021.0814 (pp. 34-37)

Haoguang Ma, Yanjie Meng, Yanyan Wu, Xibiao Zhang, Chonghui Dan, Meimei Luo, Qiang Li: Inhibition of osteosarcoma cell proliferation by matrine (MT) via targeting histone H3 lysine 27 trimethylation and AMPK activation
doi: 10.1691/ph.2021.0718 (pp. 38-41)

Reviews

Chunyin Tang, Luxin Li, Jiayi Shi, Dan Wu, Meng Wang, Yan Wu, Xiaohuan Yuan: Curcumin in age-related diseases
doi: 10.1691/ph.2020.0760 (pp. 534-539)

Chao Z, Xiaochen S, Shuyue W, Xiao S, Yaohui Y, Fei G, Lei S:A review about industrialization of Chinese materia medica decoction pieces
doi: 10.1691/ph.2020.0647 (pp. 540-547)

Isawa M, Kajiyama M, Tominaga K, Nakada H, Aomori T, Mochizuki M: Review of clinical studies on the nocebo effect
doi: 10.1691/ph.2020.0642 (pp. 548-553)

Original Articles

Shinmachi K, Takahashi Y, Kaneuji Y, Kawamura R, Kohama K, Hieda Y, Goromaru T, Eto S, Murakami T, Maeda Y: Effect of aluminium ion on bioavailability of levofloxacin following oral administration of cilexetil ester of levofloxacin as prodrug in rats
doi: 10.1691/ph.2020.0601 (pp. 554-558)

Fang Yuan, Xiaolin Liang, Xiaoqing Chen, Xiaoling Qin, Changji Tan, Laiyou Wang: CYP2C19 is involved in the effect of Wuzhi tablet (Schisandra sphenanthera extract) and its constituents on the pharmacokinetics of intravenous voriconazole
doi: 10.1691/ph.2020.0635 (pp. 559-564)

Ji-Hye Ko, Nari Lee, Hyun-Kyu Kang, Bong Seok Kim, Jung No Lee, Chang-Gu Hyun: Anti-melanogenic effects of hot-water extracts from Torreya nucifera via MAPKs and cAMP signaling pathway on B16F10 cells
doi: 10.1691/ph.2020.0522 (pp. 565-570)

Fang Xie, Li Teng Jiajie Xu, Jianjian Lu, Chao Zhang, Liya Yang, Xiaoyang Ma, Minghao Zhao: Interleukin-10 modified bone marrow mesenchymal stem cells prevent hypertrophic scar formation by inhibiting inflammation
doi: 10.1691/ph.2020.0572 (pp. 571-575)

Shengjun Jiang, Liqin Xu: Exosomes from gingival mesenchymal stem cells enhance migration and osteogenic differentiation of pre-osteoblasts
doi: 10.1691/ph.2020.0652 (pp. 576-580)

Hailun Zheng, Ajie Zhang, Dapeng Li, Xiquan Ke, Qizhi Wang, Shanjun Yan, Yongju Xue, Xiaojing Deng: Aloperine can reverse the cisplatin resistance of colorectal cancer cells via suppressing the HIF-1α/ERK signaling pathway
doi: 10.1691/ph.2020.0672 (pp. 581-585)

Yirui Huang, Meijuan Xiao, Zusen Ye, Zhao Han, P. S. Reinach, Jianhua Cheng:
2-(-2-Benzofuranyl)-2-imidazoline reciprocally regulates Th17/Treg balance induced by ischemic stroke rats
doi: 10.1691/ph.2020.0634 (pp. 586-589)

Yan-Qiu Xu, Wen Lv, Hong-Juan Wu, Suo-Fang Shi: Ginsenoside regulates Treg/Th17 cell ratio and inhibits inflammation to treat COPD
doi: 10.1691/ph.2020.0696 (pp. 590-594)

Koshishi T, Koinuma M, Takagi A, Nakamura: Pharmacological considerations in antipsychotic drug selection for prevention of drug-induced dysphagia
doi: 10.1691/ph.2020.0735 (pp. 595-598)

Yokota T, Yoshikawa N, Arimori K, Ideda R: Retrospective analysis of risk factors for liposomal amphotericin B-associated nephrotoxicity
doi: 10.1691/ph.2020.0731 (pp. 599-601)

Kanabayashi Y, Amaya F, Ikoma K, Ueno H, Tabuchi Y, Ishikawa T, Takayama K, Taguchi T: Predictors of the usefulness of mirogabalin for neuropathic pain: a single-institution retrospective study
doi: 10.1691/ph.2020.0741 (pp. 602-605)

Lauze X, Mauriņa B, Šidlovska V: Pharmacy in Latvia during the occupation regime of Nazi Germany (1941-1945)
doi: 10.1691/ph.2020.0069 (pp. 606-610)

Kurkiewicz S, Pietryja MJ, Dzierzęga-Lęcznar A, Stępień K, Kurkiewicz M, Błońska-Fajfrowska B, Boryczka S: Contemporary analytical techniques reveal the secret composition of a 19^th century Jerusalem Balsam
doi: 10.1691/ph.2020.0098 (pp. 611-617)

Reviews

Noe CR, Handschuh P, Wolfslehner L, Noe CA, Noe-Letsching M, Soucek-Noe D, Lanzenberger R:
The “sugar dilemma”
doi: 10.1691/ph.2020.0684 (pp. 456-462)

Vlad RA, Hancu G, Ciurba A, Antonoaea P, Rédai EM, Todoran N, Silaşi O, Muntean DL:
Cannabidiol – therapeutic and legal aspects
doi: 10.1691/ph.2020.0076 (pp. 463-469)

Yan Ma, Yue Shen, Bin Zhu, Dan Li, Jiyong Liu: Application of nanotechnology in circumventing immunotolerance
doi: 10.1691/ph.2020.0040 (pp. 470-477)

Original Articles

Feng Wu, Xiuli Zhao, Siyang Ni, Bo Yang: A LC-MS/MS validated method for determination of azithromycin in human tears and its application to an ocular pharmacokinetic study
doi: 10.1691/ph.2020.0538 (pp. 478-482)

Lili Wang, Shuyu Liu, Ziyao Gao: Crystal structure, dissolution and hygroscopicity of a novel cocrystal hydrate of
berberine hydrochloride with L(+)-lactic acid
doi: 10.1691/ph.2020.0079 (pp. 483-487)

Nishida S, Hayashi Y, Hirai K, Takekoshi A, Yamada Y, Kobayashi R, Shimizu S, Niwa T, Hayashi H, Shimohata T, Sugiyama T, Suzuki A: Effect of therapeutic plasma exchange on phenytoin plasma concentration in patients receiving intravenous fosphenytoin therapy
doi: 10.1691/ph.2020.0525 (pp. 488-490)

Wei Ji, Hengli Zhao, Shaomei Yang, Qing Wen, Kun He: Pharmacokinetics and tolerability of intravenous pasaconazole in healthy Chinese volunteers: a randomized, open-label and single-dose study
doi: 10.1691/ph.2020.0512 (pp. 491-493)

Lejing Miao, Pei Yu, Jing Huang, Zehang Zhuang, Haihua Xiao, Zhiqiang Yu, Xiqiang Liu: Non-classical platinum-based compound 56MESS, with preferential cytotoxic effect on oral cancer cells by downregulating FACL4 expression
doi: 10.1691/ph.2020.0481 (pp. 494-499)

Jian-Feng Lu, Lian-Gang Qi, Xiao-Bo Zhu, Yi-Xin Shen: LncRNA RMRP knockdown promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-206/CDK9 axis
doi: 10.1691/ph.2020.0591 (pp. 500-504)

Qinlong Ji, Shanhong Qi, Chao Li, Xiangdong Kong, Qiang Zheng: Dexmedetomidine suppresses oxidative stress and inflammation of nucleus pulposus cells by activating the Pl3K/Akt signaling pathway
doi: 10.1691/ph.2020.9927 (pp. 505-509)

Nagai K, Fukuno S, Miura T, Uchino Y, Sehara N, Konishi H: Reduced cytotoxicity in doxorubicin-exposed HepG2 cells pretreated with menthol due to upregulation of P-glycoprotein
doi: 10.1691/ph.2020.0448 (pp. 510-511)

Shuo Wu, Yao Zhang, Yan Zhang, Lizhan Chen, Xi Xu, Yinli Dang, Xinyu Ti: Phillygenin regulates proliferation and apoptosis of non-small cell lung cancer through by AMPK/ERK/NF-κB axis
doi: 10.1691/ph.2020.0558 (pp. 512-515)

Wang Fu-Sang, Zheng Xiao-Han, Zou Yang, Chen Ting-Ting, Sun Chao, Ling Jing-Yi, Zou Jian-Jun: Efficacy and safety of dual versus mono antiplatelet therapy in patients with stroke or transient ischemic attack: An updated meta-analysis of 18 randomized controlled trials
doi: 10.1691/ph.2020.0683 (pp. 516-523)

Ohyama K, Arai H, Sugiura M, Hori Y: Psoriasis associated with ACE inhibitors: an analysis of the FAERS database
doi: 10.1691/ph.2020.0606 (pp. 524-526)

Kambara H, Hosohata K, Nakatsuji T, Ueno S, Oyama S, Inada A, Niinomi I, Wakabayashi T, Iwanaga K: Safety profile of vonoprazan compared with proton pump inhibitors: insight from a pharmacovigilance study
doi: 10.1691/ph.2020.0604 (pp. 527-530)

Letter to the editor

Ayoub BM, Ashoush N, Tadros MM, El Zahar NM, Hendy MS, Mowaka S: Rosuvastatin dose should be case individualized: An observation from inherited hypercholesterolemia case study
doi: 10.1691/ph.2020.0611 (pp. 531-532)

Original Articles

Xiao-Guang Yang, Yan-Feng Li, Yan-Jun Wang, Rui-Heng Kong, Dun Wang: Application of novel pH sensitive isoniazid-heptamethine carbocyanine dye conjugates against prostate cancer cells
doi: 10.1691/ph.2020.0521 (pp. 412-416)

Makoni PA, Kasongo KW, Walker RB: Preformulation studies of efavirenz with lipid excipients using thermal and spectroscopic techniques
doi: 10.1691/ph.2020.0053 (pp. 417-423)

Jiangfei Chen, Suhang Guo, Xianzhu Yu, Jinxiu Lei, Tao Xu, Suyan Zhu, Lu Chen,
Ping Xu, Xuan Zhou, Lushan Yu: Metabolic interactions between flumatinib and the CYP3A4 inhibitors erythromycin, cyclosporine, and voriconazole
doi: 10.1691/ph.2020.0068 (pp. 424-429)

Suiqiao Zhao, Chunyan Zhang, Zhuang Pi, Ruibing Li, Ping Han, Lixin Guo: Oxycodone protects cardiomyocytes from ischemia-reperfusion-induced apoptosis via Pl3K/Akt pathway
doi: 10.1691/ph.2020.0497 (pp. 430-435)

Jia Liu, Yu-Guang Wang, Shu-Yan Yu, Chun-E Li, Si-Meng Kang: Protective effect of acacetin in human periodontal ligament cells via regulation of autophagy and inflammation
doi: 10.1691/ph.2020.0435 (pp. 436-439)

Xuan Huang, Muchi Xu, Kejia Li, Fangxiu Luo, Haiqin Zhu: Nitidine chloride efficiently induces autophagy and apoptosis in melanoma cells via AMPK-mTOR signaling pathway
doi: 10.1691/ph.2020.0478 (pp. 440-442)

Arsić J, Krajnović D: Portable medicine chests and supply of medicines in Serbia from the 1830s to the mid-20^th century: analysis of medicines list
doi: 10.1691/ph.2020.0039 (pp. 443-454)

Original Articles

Otto F, van Hoogevest P, Syrowatka F, Heinl V, Neubert RHH: Assessment of the applicability of HLB values for natural phospholipid emulsifiers for preparation of stable emulsions
doi: 10.1691/ph.2020.9174 (pp. 365-370)

Togami K, Yamaguchi K, Tada H, Chono S: Assessment of transporter-mediated efflux of nintedanib using in vitro cell line models of idiopathic pulmonary fibrosis
doi: 10.1691/ph.2020.0048 (pp. 371-374)

Ayoub BM, Ramadan E, Ashoush N, Tadros MM, Hendy MS, Elmazar MM,  Mousa SA: Avoiding COVID-19 complications with diabetic patients could be achieved by multi-dose Bacillus Calmette-Guérin vaccine: a case study of beta cells regeneration
doi: 10.1691/ph.2020.0494 (pp. 375-380)

Ling Ma, Mei Zhong, Guihua Jiang, Fei Long, Weiling Wu, Yunbin Jiang: Elucidation of the active ingredients of Lamiophlomis herba against hemorrhage based on network pharmacology and tail snipping model in mice
doi: 10.1691/ph.2020.0507 (pp. 381-384)

Li Yuetong, Li Shangzhu, Hu Qinglin, Huang Pingping: Salidroside inhibits proliferation, migration and invasion of human pancreatic cancer PANC1 and SW1990 cells through the AKT and ERK signaling pathway
doi: 10.1691/ph.2020.0556 (pp. 385-388)

Fengli Zhang, Yanfen Yin, Tiantian Ni, Mei Zhang, Zhou Zhou, Xin Sun, Wanghao Kuang, Ping Li: Treatment effect of apatinib combined chemotherapy as second-line or above therapy in patients with advanced gastric cancer or adenocarcinoma of the gastroesophageal junction
doi: 10.1691/ph.2020.0403 (pp. 389-394)

Yunbo Fu, Yuanxiao Yang, Jianhong Shi, Kausik Bishayee, Luning Lin, Yiyou Lin, Yehui Zhang, Liting Ji, Changyu Li: Acori tatarinowii rhizoma extract ameliorates Alzheimer’s pathological syndromes by repairing myelin injury and lowering Tau phosphorylation in mice
doi: 10.1691/ph.2020.0492 (pp. 395-400)

Hui Gong, Ying Chen, Dongchu Zhou: Prognostic significance of metformin treatment in endometrial cancer: a meta-analysis
doi: 10.1691/ph.2020.0346 (pp. 401-406)

Xiang Yu, Na Li, Yayi Li: Were it business opportunities or hidden risks: Observations on clinical trials and marketing authorizations of Gilead Science’s remdesivir in China
doi: 10.1691/ph.2020.0549 (pp. 407-410)

Reviews

Friedrich C, Helmstädter A: Seventy-five volumes of  ֦^DiePharmazie֞ – a historical review
doi: 10.1691/ph.2020.0449 (pp. 289-293)

Röder E: Medicinal plants containing pyrrolizidine alkaloids in the New Kreuterbuch by Leonhart Fuchs (1543)
doi: 10.1691/ph.2020.0062 (pp. 294-298)

Raal A, Meos A, Hinrikus T, Heinämäki J, Romāne E, Gudienė V, Jakštas V, Koshovyi O, Kovaleva A, Fursenco C: Dragendorff’s reagent: Historical perspectives and current status of a versatile reagent introduced over 150 years ago at the University of Dorpat, Tartu, Estonia
doi: 10.1691/ph.2020.0438 (pp. 299-306)

Muankaew C, Saokham P, Jansook P, Loftsson T: Self-assembly of cyclodextrin complexes: detection,
obstacles and benefits
doi: 10.1691/ph.2020.0405 (pp. 307-312)

Original Articles

Li-Hua Wang, Lin Sui, Peng-Hui Zhao, Hai-Di Ma, Jia-Yuan Liu, Zhen Wei, Zai-Ji Zhan, Yong-Li Wang: A composite of graphene oxide and iron oxide nanoparticles for targeted drug delivery of temozolomide
doi: 10.1691/ph.2020.9170 (pp. 313-317)

Pan H, Li S, Li M, Tao Q, Jia J, Li W, Wang L, Guo Z, Ma K, Liu Y, Cui C: Anti-CD19 mAb-conjugated human serum albumin nanoparticles effectively deliver doxorubicin to B-lymphoblastic leukemia cells
doi: 10.1691/ph.2020.0026 (pp. 318-323)

Martínez-Rosas JR, Díaz-Torres R, Ramírez-Noguera P, López-Barrera LD, Escobar-Chavez JJ, Ángeles ER: PLGA nanoparticles of a new cinnamic acid derivative inhibits cellular proliferation on breast cancer cell line MCF-7 in a PPARγ dependent way
doi: 10.1691/ph.2020.0450 (pp. 324-328)

Takano M, Higashi M, Baba S, Kawami M, Yumoto R:
Transport of ribavirin in human myelogenous leukemia cell line K562
doi: 10.1691/ph.2020.0440 (pp. 329-334)

Yanhui Chu, Luxin Li, Yong Liu, Yan Wu, He Bai, Jieting Liu, Xiaohuan Yuan, Zhen Zhang:
FGF1 inhibits H₂O₂-induced mitochondrion-dependent apoptosis in H9c2 cells
doi: 10.1691/ph.2020.0427 (pp. 335-338)

Yamaki K, Terashi M, Ogura S, Inoue S, Naka N, Nakagaki T, Oka N, Koyama Y:
Anti-allergic effect of the Src family kinase inhibitor saracatinib
doi: 10.1691/ph.2020.9949 (pp. 339-343)

Juan Li, Xiao-Yu Cheng, Hui Yang, Li Li, Yang Niu, Jian-Qiang Yu, Wei-Qi Li, Yao Yao: Matrine ameliorates cognitive deficits via inhibition of microglia mediated neuroinflammation in an Alzheimer’s disease mouse model
doi: 10.1691/ph.2020.0395 (pp. 344-347)

Lili Yang: Physcion 8-O-β-glucopyranoside exerts carcinostasis ability in Ishikawa cells via regulating Inc-SLC4A1-1/H3K27ac/NFκB pathway
doi: 10.1691/ph.2020.9608 (pp. 348-352)

Reviews

Wei Li, Kewei Yu, Shujuan Sun: Novel oral hypoglycemic agents SGLT-2 inhibitors: cardiovascular benefits and potential mechanisms
doi: 10.1691/ph.2020.9634 (pp. 224-229)

Wei Li, Xiaoqing Zhang, Yan Sun, Zhaohua Liu: Recent clinical advances of glucokinase activators in the treatment of diabetes mellitus type 2
doi: 10.1691/ph.2020.0409 (pp. 230-235)

Original Articles

Tanaka S, Uchida S, Hakamata A, Miyakawa S, Odagiri K, Inui N, Watanabe H, Namiki N: Simultaneous LC-MS analysis of plasma concentrations of sildenafil, tadalafil, bosentan, ambrisentan, and macitentan in patients with pulmonary arterial hypertension
doi: 10.1691/ph.2020.0021 (pp. 236-239)

Novak A, Gutiérrez-Zamora M, Pérez-Lozano P, Suñé-Negre JM, Llop JM, Ticó JR, Miñarro M, García-Montoya E, van Schepdael A: Study of tocopherol content and its potential antioxidant activity in commercial lipid emulsions for parenteral nutrition
doi: 10.1691/ph.2020.0038 (pp. 240-241)

Yonghe Wang, Yunxia Zheng, Yuchen Hao: Rucaparip (Rubraca^®) induces necrosis via upregulating the expression of RIP1 and RIP3 in ovarian cancer cells
doi: 10.1691/ph.2020.9827 (pp. 242-245)

Jia-Lu Zheng, Shuang-Shuang Wang, Ke-Ping Shen, Xiao-Wei Huang, Miao Li, Lei Chen, Xiao Peng, Hong-Mei An, Bing Hu: Ursolic acid potentiated oxaliplatin to induce apoptosis in colorectal cancer RKO cells
doi: 10.1691/ph.2020.0417 (pp. 246-249)

Zhixin Liu, Youjie Li, Gaohan She, Xiaofeng Zheng, Liying Shao, Pingyu Wang, Min Pang, Shuyang Xie, Yunxiao Sun: Resveratrol induces cervical cancer HeLa cell apoptosis through the activation and nuclear translocation promotion of FOXO3a
doi: 10.1691/ph.2020.0386 (pp. 250-254)

Yifeng Ni, Hao Zhang, Jing Zhang, Zhi Li, Zubing Li: Inhibition of JAK2 by AG490 promotes TNF-α-induced apoptosis by inhibiting autophagy in MC3T3- E1 cells
doi: 10.1691/ph.2020.0375 (pp. 255-260)

Rui Wu, Xi Yang, Qian Zhou, Wenyan Yu, Minwei Li, Jianer Wo, Weiguang Shan, Hong Zhao, Yan Chen, Zhajun Zhan: Aurovertin B exerts potent antitumor activity against triple-negative breast cancer in vivo and in vitro via regulating ATP synthase activity and DUSP1 expression
doi: 10.1691/ph.2020.0380 (pp. 261-265)

Yuanyuan Duan, Yan Zhang, Wen Peng, Pengcheng Jiang, Zhaoqun Deng, Chenguang Wu: MiR-7-5p and miR-451 as diagnostic biomarkers for papillary thyroid carcinoma in formalin-fixed paraffin-embedded tissues
doi: 10.1691/ph.2020.0335 (pp. 266-270)

Wanqiang Chen, Shaohong Li, Qi Liu, Yusheng Yang, Lushan Wei, Yaqin Lu: MicroRNA-342-5p protects against myocardial ischemia-reperfusion injury by targeting the GPRC5A pathway
doi: 10.1691/ph.2020.0383 (pp. 271-274)

Na-Na Li, Tao Cao, Fei Yu, Lian Luo, Ping Liu: MiR-520c-3p alleviates LPS-induced A549 cell and mice lung injury via targeting NLRC5
doi: 10.1691/ph.2020.0355 (pp. 275-278)

Ueki T, Sanematsu E, Furuya Y, Shinohara Y, Murakami Y, Miyazaki A, Sakamoto Y, Nakashima MN, Nakashima M: Relationship between vancomycin-associated nephrotoxicity and the number of combined nephrotoxic agents
doi: 10.1691/ph.2020.0393 (pp. 279-283)

Lei Zheng, Ye Han, Yuyao Guan, Xiaoli Zhang, Chao Song, Jing Yang: Risks in clinical applications of oseltamivir phosphate in the real world
doi: 10.1691/ph.2020.0352 (pp. 284-287)

Review

Zhang W, Zhang P, Wang G, Cheng W, Chen J, Zhang X: Recent advances of therapeutic targets and potential drugs of COVID-19
doi: 10.1691/ph.2020.0431 (pp. 161-163)

Original Articles

Maree S, du Preez JL, du Plessis LH, du Plessis J, Gerber M: A novel HPLC method developed and validated for the detection and quantification of atorvastatin, fluvastatin, pitavastatin and pravastatin during transdermal delivery studies
doi: 10.1691/ph.2020.0007 (pp. 164-166)

Pajaziti B, Petkovska R, Andrási M, Nebija D: Application of the capillary zone electrophoresis (CZE) and capillary gel electrophoresis (CGE) for the separation of human insulin, insulin lispro and their degradation products
doi: 10.1691/ph.2020.9188 (pp. 167-171)

Ezquer-Garin C, Ferriols-Lisart R, Martinez-López LM, Sangrador-Pelluz C, Nicolás-Picó J, Alós-Almiñana M: Stability of tedizolid phosphate-sodium rifampicin and tedizolid phosphate-meropenem admixtures in intravenous infusion bags stored at different temperatures
doi: 10.1691/ph.2020.9155 (pp. 172-176)

Isagawa S, Shiohira H, Hokama N, Nitta H, Yoshida T, Masamoto H, Aoki Y, Nakamura K: Measurement of zinc concentration in blood and breast milk of a Wilson’s disease patient taking zinc acetate
doi: 10.1691/ph.2020.9765 (pp. 177-178)

Miyashiro CA, Bernegossi J, Bonifácio BV, de Toledo LG, Ramos MAS, Bauab TM, Chorilli M: Development and characterization of a novel liquid crystalline system containing sodium alginate for incorporation of trans-resveratrol intended for treatment of buccal candidiasis
doi: 10.1691/ph.2020.9165 (pp. 179-185)

Yanjie Qin, Nanxi Wang, Fen Chen, Xuemei Han, Ying Zhu, Ying Rang, Xuejia Zhai, Yongning Lu: Effects of cyclosporine A on the pharmacokinetics and toxicities of irinotecan mediated by UGT1A1 in vitro and in vivo
doi: 10.1691/ph.2020.0316 (pp. 186-190)

Ishida T, Morisawa S, Iizuka M, Fujita H, Jobu K, Morita Y, Miyamura M: Juzentaihoto extract suppresses adipocyte hypertrophy and improves hyperglycemia in KKAy mice
doi: 10.1691/ph.2020.9950 (pp. 191-194)

Yan-Yang Jin, Si-Qiao Tong, Ming Tong: Erdafitinib exerts the anticancer effect on urothelial carcinoma via induction of autophagy
doi: 10.1691/ph.2020.9911 (pp. 195-197)

Congcong Yu, Liuliu Pan, Guangbao Wang, Ziyao Cai, Yancan Zhou, Xuyong Zheng, Ce Chen, Xiaodan Zhang: Silybin enhances the blood concentration of brexpiprazole in rats by downregulating expression of CYP3A4 and CYP2D6
doi: 10.1691/ph.2020.9935 (pp. 198-200)

Meng-Jiao Du, Jian-Ping Chen, Bo-Wen Lian, Wen-Jie Mei, Jia-Xian Yu, Li-Shi Chen, Shan-Bin Deng, Yan-Mei Zhong, Chu-Qin Yu: Cardioprotective effects of timosaponin B-ll isolated from Anemarrhena rhizome in a zebrafish model
doi: 10.1691/ph.2020.9869 (pp. 201-204)

Suzuki K, Sato Y, Nakahara R, Tatsuta R, Tanaka R, Itoh H: Venous thromboembolisms and rheology in ovarian cancer patients after postoperative adjuvant paclitaxel and carboplatin therapy
doi: 10.1691/ph.2020.9908 (pp. 205-207)

Li LY, Ma L, Dong WL: Total glucosides of paeony (Paeonia lactiflora) alleviates blood-brain barrier disruption and cerebral ischemia/reperfusion injury in rats via suppressing inflammation and apoptosis
doi: 10.1691/ph.2020.0324 (pp. 208-212)

Yifeng Ni, Hao Zhang, Zhi Li, Zubing Li: Connective tissue growth factor (CCN2) inhibits TNF-α-induced apoptosis by enhancing autophagy through the Akt and Erk pathways in osteoblasts
doi: 10.1691/ph.2020.0336 (pp. 213-217)

Yamashita K, Ogihara T, Hayashi M, Nakagawa T, Ishizaki Y, Kume M, Yano I, Niigata R, Hiraoka J, Yasui H, Nakamura T: Association between dexamethasone treatment and alterations in serum concentrations of trace metals
doi: 10.1691/ph.2020.0341 (pp. 218-222)

Review

Di Liu, Yun-Zhao Li, Hui Wu, Jun Yang, Jian Yang, Jia-Wang Ding, Jing Zhang, Zhi-Xing Fan, Chao-Jun Yang: Duration of dual antiplatelet therapy after percutaneous coronary intervention with implantation of second-generation drug-eluting stent: A meta-analysis of randomized controlled trials
doi: 10.1691/ph.2020.0301 (pp. 113-117)

Original Articles

Zengjun Wang, Zhuowei Zhao, Nauman Rahim Khan, Zhen Hua, Junyi Huo, Yanhui Li: Microwave assisted chitosan-polyethylene glycol hydrogel membrane synthesis of curcumin for open incision wound healing
doi: 10.1691/ph.2020.9179 (pp. 118-123)

Tianyu Chen, Tianqiang Wu, Ningxi Li, Yichun Jiang, Huanli Yin, Min Wu: Simulation-based comparison of Biopharmaceutics Classification System and drug structure
doi: 10.1691/ph.2020.9874 (pp. 124-130)

Qiying Shen, Huan Shu, Xiaoling Xu, Gaofeng Shu, Yongzhong Du, Xiaoying Ying: Tofacitinib citrate-based liposomes for effective treatment of rheumatoid arthritis
doi: 10.1691/ph.2020.9154 (pp. 131-135)

Roosendaal J, Venekamp N, Lucas L, Rosing H, Beijnen JH: Development and validation of an LC-MS/MS method for the quantification of imatinib and imatinib-d8 in human plasma for the support of an absolute bioavailability microdose trial
doi: 10.1691/ph.2020.9150 (pp. 136-141)

Miao Li, Shu-Mei Wang, Wan-Shui Wu, Dan Yan, Le-Ping Zhang, Hu-Yong Zheng: Frequency distribution of five SNPs in human GGH gene and their effects on clinical outcomes of Chinese pediatric patients with acute lymphoblastic leukemia
doi: 10.1691/ph.2020.9932 (pp. 142-146)

Yi-Zhen Tian, Ya-Peng Liu, San-Chun Tian, Su-Yin Ge, Yong-Jie Wu, Bao-Lai Zhang: Antitumor activity of ginsenoside Rd in gastric cancer via up-regulation of Caspase-3 and Caspase 9
doi: 10.1691/ph.2020.9931 (pp. 147-150)

Niinomi I, Hosohata K, Oyama S, Inada A, Wakabayashi T, Iwanaga K: Evaluation of adverse events associated with filgrastim originator and biosimilar using a spontaneous reporting system database
doi: 10.1691/ph.2020.9189 (pp. 151-153)

Usami E, Kimura M, Takenaka S, Kanda T, Teramachi H, Yoshimura T: Continuity and efficacy of real-world use of azacitidine
doi: 10.1691/ph.2020.9905 (pp. 154-158)

Letter to the editor

Yaoub, BM: COVID-19 vaccination clinical trials should consider multiple doses of BCG
doi: 10.1691/ph.2020.044 (p. 159)

Reviews

Ruqiao L, Yueli C, Xuelan Z, Huifen L, Xin Z, Danjie Z, Le S, Yanxue Z: Rhizoma Atractylodis macrocephalae: a review of photochemistry, pharmacokinetics and pharmacology
doi: 10.1691/ph.2020.9738 (pp. 42-55)

Rashid ZA, Al-Tabakha MM, Alomar MJ: Community pharmacist’s’ knowledge and practice toward oral isotretinoin prescription: a systemic review
doi: 10.1691/ph.2020.9891 (pp. 56-60)

Original Articles

Georgieva Y, Kassarova M, Kokova V, Apostolova E, Pilicheva B: Taste masking of enalapril maleate by microencapsulation in Eudragit EPO^® microparticles
doi: 10.1691/ph.2020.9123 (pp. 61-69)

Pala Kara Z, Ozturk D, Ozturk N, Orman MN, Baktir G, Okyar A: Effects of atorvastatin on talinolol absorption: A potential drug-drug interaction
doi: 10.1691/ph.2020.9904 (pp. 70-74)

Cavalcante Loureiro K, Carvalho Barbosa T, Nery M, Vinicius Chaud M, Ferreira da Silva C, Nalone Andrade L, Bani Corrêa C, Jaguer A, Ferreira Padilha F, Cordeiro Cardoso J, Souto E, Severino P: Antibacterial activity of chitosan/collagen membranes containing red propolis extract
doi: 10.1691/ph.2020.9050 (pp. 75-81)

Hanaoka S, Endo A, Hayashi H, Hirai T, Seki T: Histamine-2 receptor antagonists (H₂RA) may negatively impact ADL assessment in patients on a convalescent rehabilitation ward
doi: 10.1691/ph.2020.9858 (pp. 82-89)

Qunli Meng, Caixa Ye, Yaqin Lu: miR-181c regulates ischemia/reperfusion injury-induced neuronal cell death by regulating c-Fos signaling
doi: 10.1691/ph.2020.9856 (pp. 90-93)

Xing Wang, Leyi Li, Sinan Pei, Qian Zhu, Feihong Chen: Disruption of SSBs repair to combat platinum resistance via the JWA-targeted Pt(IV) prodrug conjugated with a wogonin derivative
doi: 10.1691/ph.2020.9815 (pp. 94-101)

Ma L, Li LY, Zhao TL: Anti-inflammatory effects of ginsenoside Rg3 on the hypertrophic scar formation via the NF-κB signaling pathway in rabbit ears
doi: 10.1691/ph.2020.9852 (pp. 102-106)

Nari Lee, You Chul Chung, Yun Beom Kim, Sung-Min Park, Bong Seok Kim, Chang-Gu Hyun: 7,8-Dimethoxycoumarin stimulates melanogenesis via MAPKs mediated MITF upregulation
doi: 10.1691/ph.2020.9735 (pp. 107-111)

Original Articles

Ikeuchi-Takahashi Y, Ito S, Itokawa A, Ota M, Onuki Y, Hidaka S, Onishi H: Preparation and evaluation of orally disintegrating tablets containing taste masked microparticles of acetaminophen
doi: 10.1691/ph.2020.9126 (pp. 2-6)

Patlolla VGR, Holbrook WP, Gizurarson S, Kristmundsdottir Þ: Evaluation of in vitro mucoadhesiveness and texture profile analysis of doxycycline in situ hydrogels
doi: 10.1691/ph.2020.9122 (pp. 7-12)

Choi I, Park SY, Lee SW, Kang Z, Jin YS, Kim IW: Dissolution enhancement of sorafenib tosylate by co-milling with tetradecanol post-extracted using supercritical carbon dioxide
doi: 10.1691/ph.2020.9120 (pp. 13-17)

Mengying Li, Dengke Yin, Jiacheng Li, Fuping Shao, Qingqing Zhang, Qianqian Jiang, Mengmeng Zhang, Ye Yang: Rosmarinic acid, the active component of Salvia miltiorrhizae, improves gliquidone transport by regulating the expression and function of P-gp and BCRP in Caco-2 cells
doi: 10.1691/ph.2020.9754 (pp. 18-22)

Hang Jing, Guo Yi-Jia, Song Bai-Li, Lin Ya-Peng, Zhang Yu-Qiao, Geng Cong,
Hao Jun-Li, Zou Jian-Jun, Yang Jie: Effect of antiplatelet pretreatment on platelet aggregation and clinical outcomes in acute ischemic stroke patients treated with recombinant tissue-type plasminogen activator
doi: 10.1691/ph.2020.9826 (pp. 23-26)

Nguyen MTH, Ott JJ, Caputo M, Keller-Stanislawski B, Klett-Tammen CJ, Linnig S, Mentzer D, Krause G: User preferences for a mobile application to report adverse events following vaccination
doi: 10.1691/ph.2020.9734 (pp. 27-31)

Ying Xue, Meizi Zeng, Yi Zheng, Lu Wang, Song Cao, Chujun Wu, Mimi Tang, Shao Liu: Gender difference in vitamin A levels in first-episode drug-naïve depression patients: a case-control and 24-weeks follow-up study
doi: 10.1691/ph.2020.9829 (pp. 32-35)

Xiaofeng Zhang, Zhiqiang Lu, Abdul KSM, Changping Ma, Keai Sinn Tan, Jovanović A, Wen Tan: Isosteviol sodium protects heart embryonic H9c2 cells against oxidative stress by activating Akt/GSK-3β signaling pathway
doi: 10.1691/ph.2020.9851 (pp. 36-40)

Original Articles

Sutthapitaksakul L, Thanawuth K, Huanbutta K, Sriamornsak P: Effect of a superdisintegrant on disintegration of orally disintegrating tablets determined by simulated wetting test and in vitro disintegration test
doi: 10.1691/ph.2022.2015 (pp. 287-290)

Ying Xiong, Xinyue Zheng, Yongmei Xie, Youling Gong, Yi Luo: Effect of cyasterone on intestinal flora in a ^BRAFV600E-mutant mouse model of colorectal cancer
doi: 10.1691/ph.2022.2422 (pp. 291-294)

Alotaibe HF, Alolaiwi LA, Almutairi A, Alsubaie N, Badri M, Khafagy ES, Alotaibi HF: Association between levothyroxine replacement therapy and osteoporosis in Riyadh, Saudi Arabia: a matched case-control study
doi: 10.1691/ph.2022.2436 (pp. 295-298)

Ahmed NJ, Alsheri AM, Almalki ZS, Alahmari A: Drug-induced weight gain in the last 10 years: a descriptive study
doi: 10.1691/ph.2022.2408 (pp. 299-301)

Hindelang V, Dimitriadis K, Saller T, Golla K, Mannell H, Hug MJ, Strobach D: A new medication-based prediction score for postoperative delirium in surgical patients: Development and proof of feasibility in a retrospective patient cohort
doi: 10.1691/ph.2022.2438 (pp. 302-306)

Tanaka H, Okuma M, Ishii T: Occurrence of voriconazole-induced cutaneous squamous cell carcinoma in Japan: data mining from different national pharmacovigilance databases
doi: 10.1691/ph.2022.2453 (pp. 307-310)

Kohama Y, Kosugi M, Arakawa M, Hidaka S: Evaluating the impact of de-escalating antimicrobial therapy in burn patients: a retrospective cohort study
doi: 10.1691/ph.2022.2455 (pp. 311-315)

Original Articles

Guesmi H, Ben Kraim J, Alatrache A, Holzgrabe U: Hydrogen-deuterium (H/D) exchange reaction of acebutolol hydrochloride in D₂O and CD₃OD solution
doi: 10.1691/ph.2022.2419 (pp. 217-223)

Wenyi Li, Qiwei Chen, Weiwei Gao, Hui Zeng: ARID1A promotes chemosensitivity to gemcitabine I npancreatic cancer through epigenetic silencing of RRM2
doi: 10.1691/ph.2022.1881 (pp. 224-229)

Qian Zhou, Ting Chen: BI6727, a polo-like kinase 1 inhibitor, synergizes with gefitinib to suppress hepatocellular carcinoma cells via a G2/M arrest mechanism
doi: 10.1691/ph.2022.2392 (pp. 230-235)

Alavez-Pérez N, Patiño-Camacho IS, Granados-Soto V, Déciga-Campos M: Melatonin synergizes with the antinociceptive effect of N-palmitoylethanolamide and paracetamol
doi: 10.1691/ph.2022.2428 (pp. 236-242)

Yamashiro K, Hosomi K, Yokoyama S, Ogata F, Nakamura T, Kawasaki: Adverse event profiles of hypomagnesemia caused by proton pump inhibitors using the Japanese Adverse Drug Event Report (JADER) Database
doi: 10.1691/ph.2022.2416 (pp. 243-247)

Ohno H, Mano S, Katagiri N, Oguri R, Miyazaki K, Ito K, Sekiya Y, Inoue K, Masuda A, Tsuzuku A, Asano F, Hirashita T, Hayashi T: Influence of using history of immune checkpoint inhibitor therapy for neutropenia caused by combination therapy of ramucirumab and docetaxel
doi: 10.1691/ph.2022.2403 (pp. 248-254)

Uwai Y, Nabekura T: Analysis of adverse drug events in patients with bipolar disorders using the Japanese Adverse Drug Event Report database
doi: 10.1691/ph.2022.2386 (pp. 255-261)

Fujimori M, Nakamura M: Association between seasonal influenza vaccines and the increased risk of acute disseminated encephalomyelitis, estimated using the Vaccine Adverse Event Reporting System
doi: 10.1691/ph.2022.2354 (pp. 262-269)

Inić S, Gašparac P: Overview of Dioscorides’ recipes in Croatian books of folk recipes
doi: 10.1691/ph.2022.2027 (pp. 270-277)

Semedo MG, Pereira AL, Pita JR: Cinchona bark and quinine in the Portuguese official pharmacopoeias (1794-2001)
doi: 10.1691/ph.2022.2034 (pp. 278-285)

Original Articles

Kryeziu TL, Haloci E, Loshaj-Shala A, Bağci U, Oral A, Stefkov GJ, Zimmer A, Basholli-Salihu M: Nanoencapsulation of Origanum vulgare essential oil into liposomes with anticancer potential
doi: 10.1691/ph.2022.1230 (pp. 172-178)

Hehe Cui, Yuejin Yang, Xiangdong Li, Wenjing Zong, Qing Li: Resveratrol regulates paracrine function of cardiac microvascular endothelial cells under hypoxia/reoxygenation condition
doi: 10.1691/ph.2022.2370 (pp. 179-185)

So Yeon Kim, Yung-Yoon Kim, In Wook Kim, Hye-Young Yun, Dong-Seok Kim: LGl3 promotes human keratinocyte migration in high-glucose environments by increasing the expression of β-catenin
doi: 10.1691/ph.2022.2359 (pp. 186-190)

Ortíz-Rodríguez MA, Oaxaca-Navarro J, Patiño-Camacho SI, García-Jiménez S, Déciga-Campos M, Martínez-Salazar MF: Plasma levels of efavirenz and frequency of the CYP2B6 516G>T polymorphism in people living with HIV-1 in Mexico
doi: 10.1691/ph.2022.2382 (pp. 191-195)

Saito Y, Takekuma Y, Komatsu Y, Sugawara M: Evaluation of risk factors for chemotherapy-induced nausea and vomiting in cisplatin and gemcitabine treatment for biliary tract cancer: acid suppressants do not prevent nausea
doi: 10.1691/ph.2022.2355 (pp. 196-201)

Ichimura T, Ogawa C, Murata H, Miyahara K, Yuge S, Tsukioka R, Kado K, Yoshimura T, Suzuki K, Nomura H, Shimizu H: Community pharmacists’ measurement of health-related quality of life in outpatients taking high-risk drugs
doi: 10.1691/ph.2022.1914 (pp. 202-206)

Schilling S, Koeck JA, Kontny U, Orlikowsky T, Erdmann H, Eisert A: High-alert medications for hospitalised paediatric patients – a two-step survey among paediatric clinical expert pharmacists in Germany
doi: 10.1691/ph.2022.12025 (pp. 207-215)

Original Articles

Ushijima H, Onoder A: Selective growth suppressive effect of pravastatin on senescent human lung fibroblasts
doi: 10.1691/ph.2022.2327 (pp. 132-136)

Weiwei Zhou, Weizhe Liu, Dinyan Zhou, Aiying Li: ITGB1 suppresses autophagy through inhibiting the mTORC2/AKT signaling pathway in H9C2 cells doi: 10.1691/ph.2022.2351(pp. 137-140)

Hongxin Sun, Yumiko Urakami-Takebayashi, Hideyuki Motohashi, Junya Nagai: Internalization of FITC-albumin in human adipose-derived stem cells: Involvement of clathrin and caveolin
doi: 10.1691/ph.2022.2340 (pp. 141-146)

Yi-Lun Wang, Jin-Jie Yang, Wan Ni: Immunomodulatory effects of sinensetin on macrophage and cyclophosphamide-induced immunosuppression in mice
doi: 10.1691/ph.2022.2321 (pp. 147-151)

Hyunmin Ko, Young Il Kim, Hyung Joon Ahn: Activin suppresses the inflammatory response of TNF-α-stimulated human umbilical vein endothelial cells
doi: 10.1691/ph.2022.2330 (pp. 152-156)

Obayashi K, Nagamine A, Yashima H, Ohshima S, Uchiyama C, Takahashi E, Takahashi Y, Araki T, Yamamoto K: Comparison of the antiemetic effect of aprepitant/granisetron and palonosetron combined with dexamethasone in gynecological cancer patients treated with paclitaxel and carboplatin combination regimen
doi: 10.1691/ph.2022.12000 (pp. 157-161)

Fukuoka T, Yamamoto Y, Usami E, Hayashi H, Utsunomiya J, Kimura M, Nakamura M, Yoshimura T, Toda Y: Expression of peripheral neuropathy after vincristine treatment related to different administration methods
doi: 10.1691/ph.2022.2329 (pp. 162-164)

Kose E, Endo H, Hori H, Hosono S, Kawamura C, Kodama Y, Yamazaki T, Yasuno N: Association of pharmacist-led deprescribing intervention with the functional recovery in convalescent setting
doi: 10.1691/ph.2022.2323 (pp. 165-170)

Original Articles

Hossain M, Hall SC, Wiggington PJ, Roth SM, Das S, Das U, Roayapalley PK, Dimmock JR:  Cytotoic benzylidene hydrazides of terephthalic acid and related compounds
doi: 10.1691/ph.2022.11072 (pp. 90-94)

Al Azzam KM: A novel and simple dynamic coating capillary electrophoresis method for the chiral separation and quantification of mitiglinide entantiomers using hydroxyethyl cellulose as a dynamic coating agent
doi: 10.1691/ph.2022.1166 (pp. 95-102)

Miyazaki Y, Uchino T, Kagawa Y: Effect of batchsize on the granule properties in planetary centrifugal granulation
doi: 10.1691/ph.2022.11059 (pp. 103-106)

Huanbutta K, Thanawuth K, Sutthapitaksakul L, Ririyaprasarth S, Cheewatanakornkool K, Maksup S, Theeratanapartkul K, Sathorn P, Phusamlee P, Kwanjaiphanich T, Sangnim T, Sriamornsak P: Development and optimization of Clinacanthus nutans liquid spray using a two-level full factorial design
doi: 10.1691/ph.2022.1236 (pp. 109-112)

Yiwei Hu, Huiting Qu, Jie He, Hongyao Zhong, Shoukai He, Peng Zhao, Leyao Zhang, Jinghua Chen, Chao Deng: Human placental mesenchymal stem cell derived exosomes exhibit anti-inflammatory effects via TLR4-mediated NF-κB/MAPK and Pl3K signaling pathways
doi: 10.1691/ph.2022.11082 (pp. 113-118)

Nagai K, Fukuno S, Moriwaki R, Kuroda H, Omotani S, Miura T, Hatsuda Y, Myotoku M, Konishi H: Influene of concurrent and staggered dosing of semi-solid nutrients on the pharmacokinetics of orally administered carbamazepine in rats
doi: 10.1691/ph.2022.1756 (pp. 119-121)

Qiong Wang, Shenghan Gao, Wensheng Zhang, Yunxia Zhao, Yi He, Wei Sun, Fenglian Zhang, Tong Yu, Lihong Zhou, Zhengliang Ye, Jiansen Su, Shunnan Zhang, Yongfa Chen: Traditional use and safety evaluation of combination Traditional Chinese Medicine in European registration: with XiaoYao tablets as an example
doi: 10.1691/ph.2022.1227 (pp. 126-131)

Original Articles

Yang L, Higashisaka K, Haga Y, Tsujino H, Nagano K, Tsutsumi Y: Alpha-cystallin B chains enhance cell migration in basal-like 2 triple-negative breast cancer cells
doi: 10.1691/ph.2022.11019 (pp. 45-47)

Jian Tang, Zhenlong Zhou, Jun Qian, Xiaoling Lin, Qiwei Liu, Qiuling Xie, Sheng Xiong: KdPT alleviates imiquimod-induced psoriasis-like skin lesion in mice via inhibiting proliferation and inflammation resoponse
doi: 10.1691/ph.2022.1970 (pp. 48-53)

Kato R, Ijiri Y: Regorafenib and reactive metabolite of sunitinib activate inflammasomes: Implications for multi tyrosine kinase inhibitor-liduced immune related adverse events
doi: 10.1691/ph.2022.1955 (pp. 54-58)

Jianhua Li, Huanxian Wu, Shidong Lv, Dongling Quan, Danni Yang, Jiahuan Xu, Boyu Chen, Baofang Ou, Shaoyu Wu, Qiang Wei: Enhanced antitumor efficacy by combining afatinib with MDV3100 in castration-resistant prostate cancer
doi: 10.1691/ph.2022.1948 (pp. 59-66)

Bosch KE, Werner CJ, Rueckbeil MV, Eisert A: Use of electronic adverse drug reaction check to identify inpatients with a high drug-associated risk of falling: a case-control study at the Department of Neurology
doi: 10.1691/ph.2022.1807 (pp. 67-75)

Takikawa M, Tanaka H, Obara T, Maeda Y, Sato M, Shimazaki Y, Mori Y, Ishigami A, Ishii T: Utility of the Berlin Initiative Study-1 equation for the prediction of serum vancomycin concentration in elderly patients aged 75 years and older
doi: 10.1691/ph.2022.1972 (pp. 76-80)

Morii Y, Fujimoto S, Nakahara R, Okawa K, Senaha H, Fujiwara K, Tsubaki M, Matzno S, Takegami M, Shimomura K, Nishida S: Effect of proton pump inhibitors on the development of hypomagnesemia induced by panitumumab
doi: 10.1691/ph.2022.1988 (pp. 81-84)

Sugisaki T, Aoyama T, Kawakami K, Yokokawa T, Kobayashi K, Suzuki W, Ogura M, Ichimura T, Chin K, Yamaguchi K, Hanaoka S, Hayashi H, Yamaguchi M: Correlation between magnesium pre-loading and cisplatin-induced nephrotoxicity in
5­­-fluorouracil/cisplatin combination therapy for espohageal cancer
doi: 10.1691/ph.2022.11038 (pp. 85-88)

Original Articles

Sehner SM, Melzig MF: Fluorometric quantification of alkaloids in the homeopathic mother tinctures of Vinca minor L. and Fumaria officinalis L.
doi: 10.1691/ph.2022.1135 (pp. 2-5)

Miura M, Tanaka S, Ikedoa M, Kawakami J, Watanabe H, Namiki N, Uchida S: Increased plasma drug concentration and decreased additional insulin secretion following oral administration of glimepiride in Spontaneously Diabetic Torii rats
doi: 10.1691/ph.2022.1950 (pp. 6-8)

Hyun Sik Kang, Jin Yong Song, Jong Heon Kim, Tae Il Park, Won Seok Choi, Ji-Yun Lee: Effects of vinpocetine on atopic dermatitis after administration via three different routes in HR-1 hairless mice
doi: 10.1691/ph.2022.1941 (pp. 9-13)

Lixia Qiang, Zhiheng Li, Gongchen Wang, Xiangshun Li, Meiyu Lv, Baocai Wang, Zhaoquan Shi, Shoude Jin: Anti-TIM1 suppresses airway inflammation and hyperresponsiveness via the STAT6/STAT1 pathways in mice with allergic asthma
doi: 10.1691/ph.2022.1670 (pp. 14-20)

Yuankai Si, Zhigui Wu, Li Gu, Hua Li, Pei Ge, Wenxian Yin, Meijuan Chen: Changes of BKCA current and vascular reactivity in vascular smooth muscle of thoracic aorta and mesenteric artery in type 2 diabetic rats
doi: 10.1691/ph.2022.1740 (pp. 21-26)

Zupanets IA, Shebeko SK, Popov SB, Zupanets KO, Zimin SM: Analgesic properties of the dry combined extract BNO 1016 in leukotriene depended hyperalgesia
doi: 10.1691/ph.2022.0505 (pp. 27-31)

Xiao Yang, Shiyue Lang, Shuqi Li, Chunlai Jiang, Jiahong Han: Preparation of icariside l and icariside ll, an exploration of their protective mechanism against cyclophosphamide-induced bone marrow suppression in mice, and their regulatory effects on immune function
doi: 10.1691/ph.2022.1771 (pp. 32-37)

Seiberth S, Berner J, Hug MJ, Strobach D: `Double Whammy`and `Triple Whammy`combinations in hospitalized surgical patients – real life data from a tertiary teaching hospital
doi: 10.1691/ph.2022.1913 (pp. 38-43)

Review

Yang Su, Fan Zhang, Wen Qin, Lun Wu, Qiuhong Wang, Genhong Cheng, Haixue Kuang: “Gut-skin”axis: understanding psoriasis from the gut
doi: 10.1691/ph.2021.1694 (pp. 523-527)

Original Articles

 Pajaziti B, András M, Nebija D, Anastova L, Petkovska R: Chemometrics approach for optimization of capillary electrophoretic conditions for the separation of insulin analogues
doi: 10.1691/ph.2021.1758 (pp. 528-531)

Sobczyński J, Chudzik-Rząd B: The in vitro photocytotoxicity of photosensitizer encapsulated by nanovehicles comprising biomimetic phospholipids
doi: 10.1691/ph.2021.0047 (pp. 523-537)

Zhengqin Dong, Qianqian Feng, Han Zhang, Qiang Liu, Jianhua Gong: Curcumin enhances drug sensitivity of gemcitabine-resistant lung cancer cells and inhibits metastasis
doi: 10.1691/ph.2021.0927 (pp. 538-543)

Mengru Lu, Junli Liang, Jinyu Liang, Hepeng Li, Peng Yang: The effects of the renin inhibitor aliskiren on neuronal toxic damage
doi: 10.1691/ph.2021.1729 (pp. 544-550)

Jiangchao Zhuang, Xie Zhou, Ting Liu, Shuai Zhang, Falei Yuan, Leifang Zhang, Zuisu Yang, Yan Chen: Astaxanthin attenuated hyperuricemia and kidney inflammation by inhibiting uric acid synthesis and the NF-κB/NLRP3 signaling pathways in potassium oxonate and hypoxanthine-induced hyperuricemia mice
doi: 10.1691/ph.2021.1731 (pp. 551-558)

Lianlian Yang, Mingyan Jiang, Ruixin Yu, Ruolan Hu, Fei Xiong, Jinrong Li: A case report of precocious puberty related to Rett syndrome and a literature review
doi: 10.1691/ph.2021.1747 (pp. 559-561)

Strobach D, Schlattl A, Schieck S, Bertsche T: QTc-time-prolongating drugs and additional risk factors for long-QT-syndrome at hospital admission of surgical patients – risk assessment by pharmacists
doi: 10.1691/ph.2021.1697 (pp. 562-566)

Reviews

Abushammalla I: Tacrolimus and herbs interactions: a review
doi: 10.1691/ph.2021.1684 (pp. 468-472)

Yang Su, Jing Li, Lun Wu, Haixue Kuang: Polysaccharides from TCM herbs exhibit potent anti-obesity effect by mediating the community structure of gut microbiota
doi: 10.1691/ph.2021.1463 (pp. 473-479)

Original Articles

Ghasemisarabbadieh M, Sigurdsson SJ, Nu Dong FV, Gizurarson S, Sveinbjörnsson BR: The effect of D-(+)-glucosamine, N-acetyl-D-glucosamie and tetraethylene glycol on the stability of oxytocin in aqueous solution
doi: 10.1691/ph.2021.1081 (pp. 480-483)

Sekiguchi M, Sagano N, Kawazoe H, Hiraga Y, Jibiki A, Yokoyama Y, Suzuki S, Nakamura T: Drug repositioning of antipsychotic drugs for cisplatin-induced pica behavior in mice
doi: 10.1691/ph.2021.1674 (pp. 484-487)

Qi Li, Zhuqing Li, Tingting Li, Yanxin Wang, Jiaxin Feng, Chengzhi Lu: Efficacy and safety of soluble guanylate cyclase stimulators in patients with heart failure: A systematic review and meta-analysis
doi: 10.1691/ph.2021.1599 (pp. 488-493)

Xuemin Li, Long Yang, Shasha Zhang, Jie Shen: The molecular mechanism of the transcriptional activator SWI regulating gene ARID1B affecting swallowing dysfunction after stroke in rats
doi: 10.1691/ph.2021.1602 (pp. 494-498)

Lijun Tao, Lina Chen, Yanmin Pei, Ping Ma, Qinbin Xu, Jialing Wang, Yang Yu, Jiang Cheng, Ru Zhou: Vasodilatory effects of betaine on isolated rat pulmonary artery rings
doi: 10.1691/ph.2021.1392 (pp. 499-502)

Liuliu Pan, Xiaodan Zhang, Danhan Wang, Min Huang, Qiusui Huang, Ping Duan, Jie Mei: DCLK1 might be a therapeutic target of osthole against cervical cancer
doi: 10.1691/ph.2021.1641 (pp. 503-506)

Jing-Jing Yu, Fei Wu, Rui-Rui Ma, Tian-Jin Wu, Yuan Zhang, Zhen-Hua Ying: The effects of iguratimod combined with methotrexate and hydroxychloroquine on bone mineral density in patients with rheumatoid arthritis
doi: 10.1691/ph.2021.1630 (pp. 507-510)

Lin Zheng, Jiamin Du, Fujing Ge, Meijia Qian, Bo Yang, Qiaojun He, Qinjie Weng, Hong Zhu: The calcimimetic agent cinacalcet inhibits hepatocellular carcinoma via YAP/TAZ suppression
doi: 10.1691/ph.2021.1646 (pp. 511-514)

Ohyama K, Hirakawa K, Sasazaki K, Tanaka H, Hori Y, Takeuchi H: Time-to-onset of diabetes with everolimus use: analysis of a spontaneous reporting system database
doi: 10.1691/ph.2021.1624 (pp. 515-518)

Bach-Rojecky L, Lackovic Z: A century of phage therapy: from novel discoveries about the past to the challenges of the today
doi: 10.1691/ph.2021.1114 (pp. 519-521)

Review

Yangni Li, Yishu Zhang, Xuran Li, Yanfen Huang, Weiyan Chen, Lan He, Yuyan Zhang: Status of hypoxia-inducible factor-1α expression in non-small cell lung cancer
doi: 10.1691/ph.2021.1524 (pp. 404-411)

Original Articles

 Xuan GS, Zhan JH, Zhang AM, Li W, Zheng K: Inhibition of carbonic anhydrase ll by sulfonamide derivatives
doi: 10.1691/ph.2021.1590 (pp. 412-415)

Baba S, Yumoto R, Kawami M, Takano M: Functional expression of equilibrative and concentrative nucleoside transporters in alveolar epithelial cells
doi: 10.1691/ph.2021.1017 (pp. 416-421)

Yujiao He, Xiao Liu, Maolin Huang, Zheng Wei, Mengyu Zhang, Mengtao He, Zhebin Zheng, Hongbo Dong, Deming Liu: Oleanolic acid inhibits the migration and invasion of hepatocellular carcinoma cells by promoting microRNA-122 expression
doi: 10.1691/ph.2021.1366 (pp. 422-427)

Lulu Cao, Xiojia Lou, Lili Zhou, Yuedan Wu: The decrease of T3 / T4 is not hypothyroidism – a new mutation of Serpina7 gene results in partial thyroglobulin deficiency
doi: 10.1691/ph.2021.1559 (pp. 428-430)

Ning Cai, Qing Yang, Dao-Biao Che, Xin Jin: 20(S)-Ginsenoside Rg3 regulates the Hedgehog signaling pathway to inhibit proliferation and epithelial-mesenchymal transition of lung cancer cells
doi: 10.1691/ph.2021.1573 (pp. 431-436)

Fujimori M, Hasegawa S, Sasaoka S. Iguchi K, Nakamura M: A study of the association between seasonal influenza vaccines and the increased risk of Guillain-Barré syndrome using Vaccine Adverse Event Reporting System, 2018-2019
doi: 10.1691/ph.2021.1578 (pp. 437-443)

Yasuda M, Tachi T, Osawa T, Watanabe H, Inoue S, Makino T, Nagaya K, Morita M, Tanaka K, Aoyama S, Kasahara S, Teramachi H, Mizui T: Risk factors for thrombocytopenia and analysis of time to platelet transfusion after azacytidine treatment
doi: 10.1691/ph.2021.1566 (pp. 444-449)

Ichimura T, Nomura H, Shimizu H, Machida Y, Suzuki K: Cost-effectiveness of primary prophylaxis of febrile neutropenia with pegfilgrastim in docetaxel, cisplatin and 5-fluorouracil therapy for esophageal cancer
doi: 10.1691/ph.2021.1031 (pp. 450-454)

Wilhelmy S, Bekel AI, Gross D, Schmidt M: Forced to join the Waffen-SS? Chief pharmacist Victor Capesius (1907-1985) and his role in Auschwitz concentration camp
doi: 10.1691/ph.2021.1070 (pp. 455-460)

Petroianu GA, Lorke DE: Vinum resinatum: Scientists and unintended consequences
doi: 10.1691/ph.2021.1080 (pp. 461-466)

Reviews

Noe CR, Noe-Letschnig M: The role of ACE2 in the renin-angiotensin-system: Etiology and therapy of COVID-19 from a pharmaceutical perspective
doi: 10.1691/ph.2021.1618 (pp. 342-350)

Qun Feng, Zhiyan Huang, Ying Sun, Rong Sun, Guimin Zhang: Stilbene glucoside: recent advances in pharmacology, bioinformatics investigation, toxicity and future opportunities
doi: 10.1691/ph.2021.1393 (pp. 351-358)

Yining Zhao, Shuangmei Liu: Bioactivity of naringin and related mechanisms
doi: 10.1691/ph.2021.1504 (pp. 359-363)

Original Articles

Bao-Xin Li, Juan Lv, Xin Zhang, Can Zhang, Shu-Qin Guo, Rui-Jiang Ma, He Wang, Yun-Liang Zhang: Hypoglycemic effect of insulin-loaded hydrogel-nanogel composite on streptozotocin-induced diabetic rats
doi: 10.1691/ph.2021.1344 (pp. 364-371)

Shu-Yan Zhou, Xin-Yi Chen, Yan Chen, Na-Na Meng, Xin Tao, Hua-Long He, Zhi-Hao Liu, Ning-Yu Wang, Luo-Ting Yu: A novel fixed-dose combination treatment for chronic hepatitis C, based on NS5A inhibitor fopitasvir and NS5B inhibitor sofosbuvir
doi: 10.1691/ph.2021.0190 (pp. 372-378)

Zhenbin Li, Xuan Chen, Xiangjun Yi: The effects of A549 and H1299 cell-derived exosomes on the proliferation and apoptosis of BEAS-2B cells
doi: 10.1691/ph.2021.1513 (pp. 379-387)

Yuxin Chen, Yanqing Wu: Reverse remodeling in a heart failure patient with cardiomegaly treated with sacubitril/valsartan: a case report
doi: 10.1691/ph.2021.1546 (pp. 388-389)

Samardžić I, Marinović I, Kuča N, Bačić Vrca V: Potential clinically significant drug-drug interactions in prescribed pharmacotherapy in an outpatient setting
doi: 10.1691/ph.2021.1561 (pp. 390-395)

Semedo MG, Pereira AL, Pita JR: The influence of German science on Clinchona and quinine research in Portugal in the second half of the 19^th
doi: 10.1691/ph.2021.1050 (pp. 396-402)

Original Articles

Tae Kon Kim: Determination of SK7324, a new class of hepatitis C virus inhibitor, in rat plasma by UPLC-MS/MS and its application to the pharmacokinetic study of SK7324
doi: 10.1691/ph.2021.1442 (pp. 295-299)

Muhana F, Al-Ani I, Al-Akayleh F, Marzouqa D, Khalili F, Al-Khatib H, Mutti H, Shalan N: Synthesis and characterization of mesoporous silica and its application as drug delivery system for glimepiride
doi: 10.1691/ph.2021.1309 (pp. 300-307)

Zhou H, Xu P, Sun Y: Pharmacokinetics of abiraterone acetate released from a tablet based
on lipid matrix in beagle dogs
doi: 10.1691/ph.2021.0171 (pp. 308-312)

Kapelka I, Shtrygol S, Koiro O, Merzlikin S, Kudina O, Yudkevych T: Effect of arachidonic acid cascade inhibitors on body temperature and cognitive functions in rats in the Morris water maze after acute cold injury
doi: 10.1691/ph.2021.1571 (pp. 313-316)

Koeck JA, Mastragelopoulos N, Just KS, Eisert A: The prevalence of ‘triple whammy’ prescriptions in surgical inpatients and associated pharmacist recommendations
doi: 10.1691/ph.2021.1323 (pp. 317-327)

Kimura M, Usami E, Teramachi H, Yoshimura T: Identifying prognostic factors associated with overall survival in second-line paclitaxel plus ramucirumab treated human epidermal growth factor receptor 2-negative advanced/recurrent gastric cancer
doi: 10.1691/ph.2021.1432 (pp. 328-333)

Mori K, Yoshida M, Tomita K, Nakamura M, Yoshimura T: Intervention of dementia support team pharmacists and its effects for the proper use of rivastigmine
doi: 10.1691/ph.2021.1534 (pp. 334-337)

Ye Yang, Junjie Li, Ping Yu, Jun Ge, Bin Liu, Juan Li: A case of the third-line treatment of lung adenocarcinoma using nivolumab combined with anlotinib
doi: 10.1691/ph.2021.1420 (pp. 338-340)

Original Articles

Feng Bian, Yufeng Zhang, Yuanlong Xie, Hongyu Fang, Mingyu Fan, Xin Wang, Hongliang Li, Tao Huang, Sheng Zhang, Lin Cai: Effects of different concentrations of metformin on osteoclast differentiation and apoptosis and its mechanism
doi: 10.1691/ph.2021.1378 (pp. 244-248)

Fenxia Li, Kangli Zhang, Meng Yu, Tongtong Chen, Liyan Ma, Hongwu Zhang, Hongmei Jia, Zhongmei Zou: Antidepressant-like effect and phytochemical profile of supercritical CO2 extract from Citri reticulatae pericarpium
doi: 10.1691/ph.2021.1408 (pp. 249-255)

Lu Yuyu, Zhang Shikun, Zhang Zhenyu, Jiang Zongdan, Sun Weihao: MiR-877-5p targets PDK-1 to promote aspirin-induced apoptosis in gastric mucosal cells
doi: 10.1691/ph.2021.0926 (pp. 256-260)

Shimanuki Y, Hashimoto H, Kawazoe H, Uozumi R, Udagawa R, Watabe D, Nakamura T, Yamaguchi M,
Terakado H: Preventive effects of self-administered cryotherapy on paclitaxel-induced peripheral neuropathy in patients with early-stage breast cancer: a propensity score analysis
doi: 10.1691/ph.2021.1398 (pp. 261-265)

Arami T, Kawazoe H, Uozumi R, Hashimoto H, Egami S, Sakiyama N, Ohe Y, Nakada H, Aomori T, Ikemura S, Yasuda H, Kawada I, Fukunaga K, Soejima K, Yamaguchi M, Nakamura T: Effect of renin-angiotensin system inhibitors on pemetrexed plus platinum-induced hematological toxicities: a multicenter retrospective study using three propensity score analyses
doi: 10.1691/ph.2021.1409 (pp. 266-271)

Grgurević D, Grugurević J, Bačić Vrca V, Marušić S, Marinović I, Barić Grugurević A: Incidence of potential drug interactions in co-prescription of statins and macrolide antibiotics in Croatia during the 14 year period
doi: 10.1691/ph.2021.1412 (pp. 272-278)

Matsuyama T, Tachi T, Katsuno H, Sugioka M, Aoyama S, Osawa T, Koyama A, Murayama A, Noguchi Y,
Yasuda M, Mizui T, Goto C, Teramachi H: Effects of polypharmacy on the prevalence of adverse drug events resulting in outpatient visits and hospitalization
doi: 10.1691/ph.2021.1427 (pp. 279-286)

Pietryjia M, Kurkiewicz S, Kurkiewicz M, Błońska-Fajfrowska B:
Hermit Treutler’s Jerusalem Balsam
doi: 10.1691/ph.2021.1024 (pp. 287-293)

Original Articles

Hong Qiang, Jianbo Li, Shuaishuai Wang, Tiange Feng, Huijie Cai, Zhilei Liu, Jingjing Yuan, Wanli Zhang, Jinjie Zhang, Zhenzhong Zhang: Distribution of systemically administered nanoparticles during acute pancreatitis: effects of particle size and disease severity
doi: 10.1691/ph.2021.0156 (pp. 180-188)

Huang F, Marzin K, Koenen R, Kammerer KP, Strelkowa N, Elgadi M, Haertter S: Effect of itraconazole on the pharmacokinetics of faldaprevir in healthy subjects
doi: 10.1691/ph.2021.0197 (pp. 189-194)

Tianming Dai, Min Wang, Pengzhen Wang, Libing Dai, Renke Dai, Qingqi Meng: Inhibition effects of eight anti-coronavirus drugs on glycosides metabolism and glycosidases in human gut microflora
doi: 10.1691/ph.2021.01005 (pp. 195-201)

Xueshan Wen, Xing Zhang, Shulan Qu, Xugang Chen, Cheng Liu, Yifu Yang: Coptisine induces G2/M arrest in esophageal cancer cell via the inhibition of p38/ERK1/2/claudin-2 signaling pathway
doi: 10.1691/ph.2021.1353 (pp. 207-207)

Yu-Ye Xue, Yun-Yang Lu, Guang-Qiang Sun, Fei Fang, Yu-Qiang Ji, Hai-Feng Tang, Peng-Cheng Qiu, Guang Cheng: CN-3 induces mitochondrial apoptosis in glioma via Ros-mediated Pl3KAKT pathway
doi: 10.1691/ph.2021.1363 (pp. 208-214)

Caihong Hu, Zhengbo Liang, Ping Lai, Xiaofang Wang, Changming Zhao: Efficacy of atezolizumab to treat non-small-cell lung cancer: a meta-analysis based on randomized clinical trials
doi: 10.1691/ph.2021.1336 (pp. 215-219)

Shu Zhang, Xianzhi Xu, Yuanhong Huang, Siyuan Sun, Chengqi Jin, Hao Ji, Dong Sun, Anzhou Xia: Anisodamine ameliorates ischemia/reperfusion-induced renal injury in rats through activation of the extracellular signal-regulated kinase (ERK) pathway and anti-apoptotic effect
doi: 10.1691/ph.2021.1302 (pp. 220-224)

Chi-Ming Liu, Zhengping Wu, Bo Pan, Lijie An, Conglei Zhu, Jiqin Zhou, Yinjie Jiang: The antiandrogenic effect of neferine, liensinine, and isoliensinine by inhibiting 5-α-reductase and androgen receptor expression via Pl3K/AKT signaling pathway in prostate cancer
doi: 10.1691/ph.2021.1301 (pp. 225-231)

Bo Cui, Zhe Yang, Shuning Wang, Mengnan Guo, Qianqian Li, Qiuhua Zhang, Xiuli Bi: The protective role of protocatechuic acid against chemically induced liver fibrosis in vitro and in vivo
doi: 10.1691/ph.2021.0909 (pp. 232-238)

Fukuoka T, Yamamoto Y, Utsunomiya J, Usami E, Kimura M, Yoshimura T, Nakamura M, Tody Y: Association between immune-related dermatologic adverse events and efficacy of pembrolizumab in non-small cell lung cancer patients
doi: 10.1691/ph.2021.01018 (pp. 239-242)

Review

Bing Chen, Yishu Zhang, Simiao Chen, Xuran Li, Jingyi Dong, Weiyan Chen, Shuiliang Tao, Weiji Yang, Yuyan Zhang: The role of vascular endothelial growth factor in ischemic stroke
doi: 10.1691/ph.2021.1315 (pp. 127-131)

Original Articles

Haiping Yao, Yanyan Wang, Jiangwen Mo, Yan Peng, Zhu Wang: Design, synthesis, and biological evaluation of isoquinolin 1-(2H)-one derivates as tankyrase-1/2 inhibitors
doi: 10.1691/ph.2021.0904 (pp. 132-137)

Farias FF, Martins VAP, Dörr FA, Trujillo LM, Pinto E: Forced degradation study and characterization of main impurities of ibuprofen soft gelatin capsules by LC-MS-QTOF
doi: 10.1691/ph.2021.0126 (pp. 138-144)

Shuai Liu, Junfeng Zhu, Chang Liu, Jiazeng Li, Li Zhang, Jian Zhao, Hongsheng Liu: Synthesis of sustained release/controlled release nanoparticles carrying nattokinase and their application in thrombolysis
doi: 10.1691/ph.2021.0155 (pp. 145-149)

Mékidèche T, Curti C, Lamy E, Jean C, Bertault Peres P, Vanelle P: Compounding and quality control of two pediatric topiramate pharmaceutical preparations
doi: 10.1691/ph.2021.0176 (pp. 150-154)

Albassam AA, Ahad A, Alsultan A, Yusufoglu HS, Foudah AI, Al-Jenoobi FI: The inhibition of CYP1A2, CYP2C9, and CYP2D6 by pterostilbene in human liver microsomes
doi: 10.1691/ph.2021.1304 (pp. 155-158)

Juncheng He, Qifeng Zhou, Xianchao Jia, Peng Zhou, Lin Chen: Immune-related expression profiles of bisphosphonates-related osteonecrosis of the jaw in multiple myeloma
doi: 10.1691/ph.2021.01013 (pp. 159-164)

Zhujun Yin, Ruirong Tan, Tianmin Yuan, Shilong Chen, Yunyun Quan, Qing Hao, Jin Zeng, Junning Zhao, Li Li: Berberine prevents diabetic retinopathy through inhibiting HIF-1α/VEGF/NF-κB pathway in db/db mice
doi: 10.1691/ph.2021.0933 (pp. 165-171)

Yifan Chen, Min Zhang, Xinghao Ji, Jinjin Zhao, Shuang Qin, Yinghua Ji, Ruijuan Fan, Yanting Liu, Ping Lu: The anti-cancer effect of metoclopramide on triple-negative breast cancer cells
doi: 10.1691/ph.2021.0977 (pp. 172-174)

Kanabayashi Y, Amaya F, Ueno H, Tabuchi Y, Ishikawa T, Takayama K, Taguchi T: Factors affecting the effect of naldemedine for opioid-induced constipation: a single-institution, retrospective analysis
doi: 10.1691/ph.2021.0959 (pp. 175-178)

Reviews

Kumar SA, Weyland Cheng: A hypothesis: Bitter taste receptors as a therapeutic target for the clinical symptoms of SARS-CoV 2
doi: 10.1691/ph.2021.0840 (pp. 43-54)

Xin-xin Zhang, Dong-sheng Zhao, Jie Wang, Hui Zhou, Lei Wang, Jin-long Mao,
Ji-xiang He: The treatment of cardiovascular diseases: a review of ferulic acid and its derivatives
doi: 10.1691/ph.2021.0958 (pp. 55-60)

Xiao-Ming Xi, Chen-Meng, Shu-Jun Xia, Rong Liu: Drug loading techniques for
exosome-based drug delivery systems
doi: 10.1691/ph.2021.0128 (pp. 61-67)

Original Articles

Tavares HS, Cardoso JF, Almeida TC, Marques MBF, Mussel WN, Lopes MCP,
Oréfice RL, Andrade SN, Varotti FP, Silva GN, da Silva GR: Spiramyin-loaded PLGA implants for the treatment of ocular toxoplasmosis: development, characterization, biocompatibility, and anti-toxoplasma activity
doi: 10.1691/ph.2021.0100 (pp. 68-76)

Witika BA, Walker RB: Preformulation characterization and identification of excipients for nevirapine loaded niosomes
doi: 10.1691/ph.2021.0137 (pp. 77-83)

Tian Deng, Na Zhang, Yi Liu, Junmin Li: Daidzein ameliorates experimental acute reflux esophagitis in rats via regulation of cytokines
doi: 10.1691/ph.2021.01003 (pp. 84-91)

Shengli Li, Likun Sun, Qian Zhou, Shuo Li, Xiaoli Liu, Juan Xiao, Yaqi Xu, Fang Wang, Yang Jiang, Chengyun Zheng: Therapeutic effect and mechanism of ibrutinib combined with dexamethasone on multiple myeloma
doi: 10.1691/ph.2021.0917 (pp. 92-96)

Yan Hou, Yingli Zhen, Qingliang Xue, Wei Wang: Astragaloside lV attenuates
TGF-β-mediated epithelial-mesenchymal transition of pulmonary fibrosis via suppressing NLRP3 expression in vitro
doi: 10.1691/ph.2021.0933 (pp. 97-102)

Zhuoheng Lu, Shengtao Li, Jia Luo, Yishuang Luo, Manyun Dai, Xiuting Zheng, Jiapeng Qiu, Julin Yang, Aiming Liu: Fenofibrate reverses liver fibrosis in cholestatic mice induced by alpha-naphthylisothiocyanate
doi: 10.1691/ph.2021.0988 (pp. 103-108)

Renzhong Hu, Yijia Guo, Yapeng Lin, Yifang Tang, Qin Tang, Xiaoqing Wang, Jie Yang, Xia Wang: Safety and efficacy of edaravone combined with alteplase for patients with acute ischemic stroke: A systematic review and meta-analysis
doi: 10.1691/ph.2021.0949 (pp. 109-113)

Higashi T, Tsukamoto H, Kodawara T, Igarashi T, Watanabe K, Yano R, Iwasaki H,
Goto N: Evaluation of risk factors for nephrotoxicity associated with high-dose vancomycin
in Japanese patients
doi: 10.1691/ph.2021.0138 (pp. 114-118)

Inić S, Flegar V: Adolf Thierry and the first pharmaceutical factory in Southeast Europe
doi: 10.1691/ph.2021.0140 (pp. 119-125)

Original Articles

Kashiwagura Y, Uchida S, Hakamata A, Watanabe H, Namiki N: In vitro transdermal permeation and in vivo transdermal absorption of domperidone cream formulations compounded from tablets as a hospital formulation
doi: 10.1691/ph.2021.0082 (pp. 2-5)

Samardzic I, Marinovic I, Matkovic I, Mamic I, Bacic Vrca V: Antimicrobial drugs involved in potential drug-drug-interactions in cardiosurgical patients
doi: 10.1691/ph.2021.0774 (pp. 6-11)

Sze-Wan Wong E, Jingjing Li, Renkai Li R, Pak-Heng Leung G, Kwok-Fu Ng J: Involvement of different α₂ adrenoceptor subtypes in effects of dexmedetomidine on porcine coronary artery
doi: 10.1691/ph.2021.0878 (pp. 12-17)

Bing Hua, Hehe Cui, Qingbo Liu, Weiping Li, Hui Chen, Hongwei Li: Nicorandil protects cardiac microvascular endothelial cells from advanced glycation end products induced cytotoxicity via promoting autophagy
doi: 10.1691/ph.2021.0831 (pp. 18-22)

Ze Guo, Jinping Gao, Xing Fan, Anping Zhang, Zaixing Wang, Xianfa Tang, Yue Chen, Huayang Tang, Hui Li: Carbamazepine-induced DiHS/DRESS syndrome leading to hemophagocytic lymphohistiocytosis in a woman carrying the HLA-B*1301 gene
doi: 10.1691/ph.2021.0808 (pp. 23-26)

Yulin Wang, Run Cheng, Xinyi Wu, Mingxing Miao: Neuroprotective and neurotrophic effects of ginkgetin and bilobalide on MPTP-induced mice with Parkinson’ disease
doi: 10.1691/ph.2021.0799 (pp. 27-33)

Feng Xiao, Shi-Ming Zhang, Yan-Ping Wang: MiR-301a is interrelated with poor prognosis and contributes to temozolomide resistance in human glioma
doi: 10.1691/ph.2021.0814 (pp. 34-37)

Haoguang Ma, Yanjie Meng, Yanyan Wu, Xibiao Zhang, Chonghui Dan, Meimei Luo, Qiang Li: Inhibition of osteosarcoma cell proliferation by matrine (MT) via targeting histone H3 lysine 27 trimethylation and AMPK activation
doi: 10.1691/ph.2021.0718 (pp. 38-41)

Reviews

Chunyin Tang, Luxin Li, Jiayi Shi, Dan Wu, Meng Wang, Yan Wu, Xiaohuan Yuan: Curcumin in age-related diseases
doi: 10.1691/ph.2020.0760 (pp. 534-539)

Chao Z, Xiaochen S, Shuyue W, Xiao S, Yaohui Y, Fei G, Lei S:A review about industrialization of Chinese materia medica decoction pieces
doi: 10.1691/ph.2020.0647 (pp. 540-547)

Isawa M, Kajiyama M, Tominaga K, Nakada H, Aomori T, Mochizuki M: Review of clinical studies on the nocebo effect
doi: 10.1691/ph.2020.0642 (pp. 548-553)

Original Articles

Shinmachi K, Takahashi Y, Kaneuji Y, Kawamura R, Kohama K, Hieda Y, Goromaru T, Eto S, Murakami T, Maeda Y: Effect of aluminium ion on bioavailability of levofloxacin following oral administration of cilexetil ester of levofloxacin as prodrug in rats
doi: 10.1691/ph.2020.0601 (pp. 554-558)

Fang Yuan, Xiaolin Liang, Xiaoqing Chen, Xiaoling Qin, Changji Tan, Laiyou Wang: CYP2C19 is involved in the effect of Wuzhi tablet (Schisandra sphenanthera extract) and its constituents on the pharmacokinetics of intravenous voriconazole
doi: 10.1691/ph.2020.0635 (pp. 559-564)

Ji-Hye Ko, Nari Lee, Hyun-Kyu Kang, Bong Seok Kim, Jung No Lee, Chang-Gu Hyun: Anti-melanogenic effects of hot-water extracts from Torreya nucifera via MAPKs and cAMP signaling pathway on B16F10 cells
doi: 10.1691/ph.2020.0522 (pp. 565-570)

Fang Xie, Li Teng Jiajie Xu, Jianjian Lu, Chao Zhang, Liya Yang, Xiaoyang Ma, Minghao Zhao: Interleukin-10 modified bone marrow mesenchymal stem cells prevent hypertrophic scar formation by inhibiting inflammation
doi: 10.1691/ph.2020.0572 (pp. 571-575)

Shengjun Jiang, Liqin Xu: Exosomes from gingival mesenchymal stem cells enhance migration and osteogenic differentiation of pre-osteoblasts
doi: 10.1691/ph.2020.0652 (pp. 576-580)

Hailun Zheng, Ajie Zhang, Dapeng Li, Xiquan Ke, Qizhi Wang, Shanjun Yan, Yongju Xue, Xiaojing Deng: Aloperine can reverse the cisplatin resistance of colorectal cancer cells via suppressing the HIF-1α/ERK signaling pathway
doi: 10.1691/ph.2020.0672 (pp. 581-585)

Yirui Huang, Meijuan Xiao, Zusen Ye, Zhao Han, P. S. Reinach, Jianhua Cheng:
2-(-2-Benzofuranyl)-2-imidazoline reciprocally regulates Th17/Treg balance induced by ischemic stroke rats
doi: 10.1691/ph.2020.0634 (pp. 586-589)

Yan-Qiu Xu, Wen Lv, Hong-Juan Wu, Suo-Fang Shi: Ginsenoside regulates Treg/Th17 cell ratio and inhibits inflammation to treat COPD
doi: 10.1691/ph.2020.0696 (pp. 590-594)

Koshishi T, Koinuma M, Takagi A, Nakamura: Pharmacological considerations in antipsychotic drug selection for prevention of drug-induced dysphagia
doi: 10.1691/ph.2020.0735 (pp. 595-598)

Yokota T, Yoshikawa N, Arimori K, Ideda R: Retrospective analysis of risk factors for liposomal amphotericin B-associated nephrotoxicity
doi: 10.1691/ph.2020.0731 (pp. 599-601)

Kanabayashi Y, Amaya F, Ikoma K, Ueno H, Tabuchi Y, Ishikawa T, Takayama K, Taguchi T: Predictors of the usefulness of mirogabalin for neuropathic pain: a single-institution retrospective study
doi: 10.1691/ph.2020.0741 (pp. 602-605)

Lauze X, Mauriņa B, Šidlovska V: Pharmacy in Latvia during the occupation regime of Nazi Germany (1941-1945)
doi: 10.1691/ph.2020.0069 (pp. 606-610)

Kurkiewicz S, Pietryja MJ, Dzierzęga-Lęcznar A, Stępień K, Kurkiewicz M, Błońska-Fajfrowska B, Boryczka S: Contemporary analytical techniques reveal the secret composition of a 19^th century Jerusalem Balsam
doi: 10.1691/ph.2020.0098 (pp. 611-617)

Reviews

Noe CR, Handschuh P, Wolfslehner L, Noe CA, Noe-Letsching M, Soucek-Noe D, Lanzenberger R:
The “sugar dilemma”
doi: 10.1691/ph.2020.0684 (pp. 456-462)

Vlad RA, Hancu G, Ciurba A, Antonoaea P, Rédai EM, Todoran N, Silaşi O, Muntean DL:
Cannabidiol – therapeutic and legal aspects
doi: 10.1691/ph.2020.0076 (pp. 463-469)

Yan Ma, Yue Shen, Bin Zhu, Dan Li, Jiyong Liu: Application of nanotechnology in circumventing immunotolerance
doi: 10.1691/ph.2020.0040 (pp. 470-477)

Original Articles

Feng Wu, Xiuli Zhao, Siyang Ni, Bo Yang: A LC-MS/MS validated method for determination of azithromycin in human tears and its application to an ocular pharmacokinetic study
doi: 10.1691/ph.2020.0538 (pp. 478-482)

Lili Wang, Shuyu Liu, Ziyao Gao: Crystal structure, dissolution and hygroscopicity of a novel cocrystal hydrate of
berberine hydrochloride with L(+)-lactic acid
doi: 10.1691/ph.2020.0079 (pp. 483-487)

Nishida S, Hayashi Y, Hirai K, Takekoshi A, Yamada Y, Kobayashi R, Shimizu S, Niwa T, Hayashi H, Shimohata T, Sugiyama T, Suzuki A: Effect of therapeutic plasma exchange on phenytoin plasma concentration in patients receiving intravenous fosphenytoin therapy
doi: 10.1691/ph.2020.0525 (pp. 488-490)

Wei Ji, Hengli Zhao, Shaomei Yang, Qing Wen, Kun He: Pharmacokinetics and tolerability of intravenous pasaconazole in healthy Chinese volunteers: a randomized, open-label and single-dose study
doi: 10.1691/ph.2020.0512 (pp. 491-493)

Lejing Miao, Pei Yu, Jing Huang, Zehang Zhuang, Haihua Xiao, Zhiqiang Yu, Xiqiang Liu: Non-classical platinum-based compound 56MESS, with preferential cytotoxic effect on oral cancer cells by downregulating FACL4 expression
doi: 10.1691/ph.2020.0481 (pp. 494-499)

Jian-Feng Lu, Lian-Gang Qi, Xiao-Bo Zhu, Yi-Xin Shen: LncRNA RMRP knockdown promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-206/CDK9 axis
doi: 10.1691/ph.2020.0591 (pp. 500-504)

Qinlong Ji, Shanhong Qi, Chao Li, Xiangdong Kong, Qiang Zheng: Dexmedetomidine suppresses oxidative stress and inflammation of nucleus pulposus cells by activating the Pl3K/Akt signaling pathway
doi: 10.1691/ph.2020.9927 (pp. 505-509)

Nagai K, Fukuno S, Miura T, Uchino Y, Sehara N, Konishi H: Reduced cytotoxicity in doxorubicin-exposed HepG2 cells pretreated with menthol due to upregulation of P-glycoprotein
doi: 10.1691/ph.2020.0448 (pp. 510-511)

Shuo Wu, Yao Zhang, Yan Zhang, Lizhan Chen, Xi Xu, Yinli Dang, Xinyu Ti: Phillygenin regulates proliferation and apoptosis of non-small cell lung cancer through by AMPK/ERK/NF-κB axis
doi: 10.1691/ph.2020.0558 (pp. 512-515)

Wang Fu-Sang, Zheng Xiao-Han, Zou Yang, Chen Ting-Ting, Sun Chao, Ling Jing-Yi, Zou Jian-Jun: Efficacy and safety of dual versus mono antiplatelet therapy in patients with stroke or transient ischemic attack: An updated meta-analysis of 18 randomized controlled trials
doi: 10.1691/ph.2020.0683 (pp. 516-523)

Ohyama K, Arai H, Sugiura M, Hori Y: Psoriasis associated with ACE inhibitors: an analysis of the FAERS database
doi: 10.1691/ph.2020.0606 (pp. 524-526)

Kambara H, Hosohata K, Nakatsuji T, Ueno S, Oyama S, Inada A, Niinomi I, Wakabayashi T, Iwanaga K: Safety profile of vonoprazan compared with proton pump inhibitors: insight from a pharmacovigilance study
doi: 10.1691/ph.2020.0604 (pp. 527-530)

Letter to the editor

Ayoub BM, Ashoush N, Tadros MM, El Zahar NM, Hendy MS, Mowaka S: Rosuvastatin dose should be case individualized: An observation from inherited hypercholesterolemia case study
doi: 10.1691/ph.2020.0611 (pp. 531-532)

Original Articles

Xiao-Guang Yang, Yan-Feng Li, Yan-Jun Wang, Rui-Heng Kong, Dun Wang: Application of novel pH sensitive isoniazid-heptamethine carbocyanine dye conjugates against prostate cancer cells
doi: 10.1691/ph.2020.0521 (pp. 412-416)

Makoni PA, Kasongo KW, Walker RB: Preformulation studies of efavirenz with lipid excipients using thermal and spectroscopic techniques
doi: 10.1691/ph.2020.0053 (pp. 417-423)

Jiangfei Chen, Suhang Guo, Xianzhu Yu, Jinxiu Lei, Tao Xu, Suyan Zhu, Lu Chen,
Ping Xu, Xuan Zhou, Lushan Yu: Metabolic interactions between flumatinib and the CYP3A4 inhibitors erythromycin, cyclosporine, and voriconazole
doi: 10.1691/ph.2020.0068 (pp. 424-429)

Suiqiao Zhao, Chunyan Zhang, Zhuang Pi, Ruibing Li, Ping Han, Lixin Guo: Oxycodone protects cardiomyocytes from ischemia-reperfusion-induced apoptosis via Pl3K/Akt pathway
doi: 10.1691/ph.2020.0497 (pp. 430-435)

Jia Liu, Yu-Guang Wang, Shu-Yan Yu, Chun-E Li, Si-Meng Kang: Protective effect of acacetin in human periodontal ligament cells via regulation of autophagy and inflammation
doi: 10.1691/ph.2020.0435 (pp. 436-439)

Xuan Huang, Muchi Xu, Kejia Li, Fangxiu Luo, Haiqin Zhu: Nitidine chloride efficiently induces autophagy and apoptosis in melanoma cells via AMPK-mTOR signaling pathway
doi: 10.1691/ph.2020.0478 (pp. 440-442)

Arsić J, Krajnović D: Portable medicine chests and supply of medicines in Serbia from the 1830s to the mid-20^th century: analysis of medicines list
doi: 10.1691/ph.2020.0039 (pp. 443-454)

Original Articles

Otto F, van Hoogevest P, Syrowatka F, Heinl V, Neubert RHH: Assessment of the applicability of HLB values for natural phospholipid emulsifiers for preparation of stable emulsions
doi: 10.1691/ph.2020.9174 (pp. 365-370)

Togami K, Yamaguchi K, Tada H, Chono S: Assessment of transporter-mediated efflux of nintedanib using in vitro cell line models of idiopathic pulmonary fibrosis
doi: 10.1691/ph.2020.0048 (pp. 371-374)

Ayoub BM, Ramadan E, Ashoush N, Tadros MM, Hendy MS, Elmazar MM,  Mousa SA: Avoiding COVID-19 complications with diabetic patients could be achieved by multi-dose Bacillus Calmette-Guérin vaccine: a case study of beta cells regeneration
doi: 10.1691/ph.2020.0494 (pp. 375-380)

Ling Ma, Mei Zhong, Guihua Jiang, Fei Long, Weiling Wu, Yunbin Jiang: Elucidation of the active ingredients of Lamiophlomis herba against hemorrhage based on network pharmacology and tail snipping model in mice
doi: 10.1691/ph.2020.0507 (pp. 381-384)

Li Yuetong, Li Shangzhu, Hu Qinglin, Huang Pingping: Salidroside inhibits proliferation, migration and invasion of human pancreatic cancer PANC1 and SW1990 cells through the AKT and ERK signaling pathway
doi: 10.1691/ph.2020.0556 (pp. 385-388)

Fengli Zhang, Yanfen Yin, Tiantian Ni, Mei Zhang, Zhou Zhou, Xin Sun, Wanghao Kuang, Ping Li: Treatment effect of apatinib combined chemotherapy as second-line or above therapy in patients with advanced gastric cancer or adenocarcinoma of the gastroesophageal junction
doi: 10.1691/ph.2020.0403 (pp. 389-394)

Yunbo Fu, Yuanxiao Yang, Jianhong Shi, Kausik Bishayee, Luning Lin, Yiyou Lin, Yehui Zhang, Liting Ji, Changyu Li: Acori tatarinowii rhizoma extract ameliorates Alzheimer’s pathological syndromes by repairing myelin injury and lowering Tau phosphorylation in mice
doi: 10.1691/ph.2020.0492 (pp. 395-400)

Hui Gong, Ying Chen, Dongchu Zhou: Prognostic significance of metformin treatment in endometrial cancer: a meta-analysis
doi: 10.1691/ph.2020.0346 (pp. 401-406)

Xiang Yu, Na Li, Yayi Li: Were it business opportunities or hidden risks: Observations on clinical trials and marketing authorizations of Gilead Science’s remdesivir in China
doi: 10.1691/ph.2020.0549 (pp. 407-410)

Reviews

Friedrich C, Helmstädter A: Seventy-five volumes of  ֦^DiePharmazie֞ – a historical review
doi: 10.1691/ph.2020.0449 (pp. 289-293)

Röder E: Medicinal plants containing pyrrolizidine alkaloids in the New Kreuterbuch by Leonhart Fuchs (1543)
doi: 10.1691/ph.2020.0062 (pp. 294-298)

Raal A, Meos A, Hinrikus T, Heinämäki J, Romāne E, Gudienė V, Jakštas V, Koshovyi O, Kovaleva A, Fursenco C: Dragendorff’s reagent: Historical perspectives and current status of a versatile reagent introduced over 150 years ago at the University of Dorpat, Tartu, Estonia
doi: 10.1691/ph.2020.0438 (pp. 299-306)

Muankaew C, Saokham P, Jansook P, Loftsson T: Self-assembly of cyclodextrin complexes: detection,
obstacles and benefits
doi: 10.1691/ph.2020.0405 (pp. 307-312)

Original Articles

Li-Hua Wang, Lin Sui, Peng-Hui Zhao, Hai-Di Ma, Jia-Yuan Liu, Zhen Wei, Zai-Ji Zhan, Yong-Li Wang: A composite of graphene oxide and iron oxide nanoparticles for targeted drug delivery of temozolomide
doi: 10.1691/ph.2020.9170 (pp. 313-317)

Pan H, Li S, Li M, Tao Q, Jia J, Li W, Wang L, Guo Z, Ma K, Liu Y, Cui C: Anti-CD19 mAb-conjugated human serum albumin nanoparticles effectively deliver doxorubicin to B-lymphoblastic leukemia cells
doi: 10.1691/ph.2020.0026 (pp. 318-323)

Martínez-Rosas JR, Díaz-Torres R, Ramírez-Noguera P, López-Barrera LD, Escobar-Chavez JJ, Ángeles ER: PLGA nanoparticles of a new cinnamic acid derivative inhibits cellular proliferation on breast cancer cell line MCF-7 in a PPARγ dependent way
doi: 10.1691/ph.2020.0450 (pp. 324-328)

Takano M, Higashi M, Baba S, Kawami M, Yumoto R:
Transport of ribavirin in human myelogenous leukemia cell line K562
doi: 10.1691/ph.2020.0440 (pp. 329-334)

Yanhui Chu, Luxin Li, Yong Liu, Yan Wu, He Bai, Jieting Liu, Xiaohuan Yuan, Zhen Zhang:
FGF1 inhibits H₂O₂-induced mitochondrion-dependent apoptosis in H9c2 cells
doi: 10.1691/ph.2020.0427 (pp. 335-338)

Yamaki K, Terashi M, Ogura S, Inoue S, Naka N, Nakagaki T, Oka N, Koyama Y:
Anti-allergic effect of the Src family kinase inhibitor saracatinib
doi: 10.1691/ph.2020.9949 (pp. 339-343)

Juan Li, Xiao-Yu Cheng, Hui Yang, Li Li, Yang Niu, Jian-Qiang Yu, Wei-Qi Li, Yao Yao: Matrine ameliorates cognitive deficits via inhibition of microglia mediated neuroinflammation in an Alzheimer’s disease mouse model
doi: 10.1691/ph.2020.0395 (pp. 344-347)

Lili Yang: Physcion 8-O-β-glucopyranoside exerts carcinostasis ability in Ishikawa cells via regulating Inc-SLC4A1-1/H3K27ac/NFκB pathway
doi: 10.1691/ph.2020.9608 (pp. 348-352)

Reviews

Wei Li, Kewei Yu, Shujuan Sun: Novel oral hypoglycemic agents SGLT-2 inhibitors: cardiovascular benefits and potential mechanisms
doi: 10.1691/ph.2020.9634 (pp. 224-229)

Wei Li, Xiaoqing Zhang, Yan Sun, Zhaohua Liu: Recent clinical advances of glucokinase activators in the treatment of diabetes mellitus type 2
doi: 10.1691/ph.2020.0409 (pp. 230-235)

Original Articles

Tanaka S, Uchida S, Hakamata A, Miyakawa S, Odagiri K, Inui N, Watanabe H, Namiki N: Simultaneous LC-MS analysis of plasma concentrations of sildenafil, tadalafil, bosentan, ambrisentan, and macitentan in patients with pulmonary arterial hypertension
doi: 10.1691/ph.2020.0021 (pp. 236-239)

Novak A, Gutiérrez-Zamora M, Pérez-Lozano P, Suñé-Negre JM, Llop JM, Ticó JR, Miñarro M, García-Montoya E, van Schepdael A: Study of tocopherol content and its potential antioxidant activity in commercial lipid emulsions for parenteral nutrition
doi: 10.1691/ph.2020.0038 (pp. 240-241)

Yonghe Wang, Yunxia Zheng, Yuchen Hao: Rucaparip (Rubraca^®) induces necrosis via upregulating the expression of RIP1 and RIP3 in ovarian cancer cells
doi: 10.1691/ph.2020.9827 (pp. 242-245)

Jia-Lu Zheng, Shuang-Shuang Wang, Ke-Ping Shen, Xiao-Wei Huang, Miao Li, Lei Chen, Xiao Peng, Hong-Mei An, Bing Hu: Ursolic acid potentiated oxaliplatin to induce apoptosis in colorectal cancer RKO cells
doi: 10.1691/ph.2020.0417 (pp. 246-249)

Zhixin Liu, Youjie Li, Gaohan She, Xiaofeng Zheng, Liying Shao, Pingyu Wang, Min Pang, Shuyang Xie, Yunxiao Sun: Resveratrol induces cervical cancer HeLa cell apoptosis through the activation and nuclear translocation promotion of FOXO3a
doi: 10.1691/ph.2020.0386 (pp. 250-254)

Yifeng Ni, Hao Zhang, Jing Zhang, Zhi Li, Zubing Li: Inhibition of JAK2 by AG490 promotes TNF-α-induced apoptosis by inhibiting autophagy in MC3T3- E1 cells
doi: 10.1691/ph.2020.0375 (pp. 255-260)

Rui Wu, Xi Yang, Qian Zhou, Wenyan Yu, Minwei Li, Jianer Wo, Weiguang Shan, Hong Zhao, Yan Chen, Zhajun Zhan: Aurovertin B exerts potent antitumor activity against triple-negative breast cancer in vivo and in vitro via regulating ATP synthase activity and DUSP1 expression
doi: 10.1691/ph.2020.0380 (pp. 261-265)

Yuanyuan Duan, Yan Zhang, Wen Peng, Pengcheng Jiang, Zhaoqun Deng, Chenguang Wu: MiR-7-5p and miR-451 as diagnostic biomarkers for papillary thyroid carcinoma in formalin-fixed paraffin-embedded tissues
doi: 10.1691/ph.2020.0335 (pp. 266-270)

Wanqiang Chen, Shaohong Li, Qi Liu, Yusheng Yang, Lushan Wei, Yaqin Lu: MicroRNA-342-5p protects against myocardial ischemia-reperfusion injury by targeting the GPRC5A pathway
doi: 10.1691/ph.2020.0383 (pp. 271-274)

Na-Na Li, Tao Cao, Fei Yu, Lian Luo, Ping Liu: MiR-520c-3p alleviates LPS-induced A549 cell and mice lung injury via targeting NLRC5
doi: 10.1691/ph.2020.0355 (pp. 275-278)

Ueki T, Sanematsu E, Furuya Y, Shinohara Y, Murakami Y, Miyazaki A, Sakamoto Y, Nakashima MN, Nakashima M: Relationship between vancomycin-associated nephrotoxicity and the number of combined nephrotoxic agents
doi: 10.1691/ph.2020.0393 (pp. 279-283)

Lei Zheng, Ye Han, Yuyao Guan, Xiaoli Zhang, Chao Song, Jing Yang: Risks in clinical applications of oseltamivir phosphate in the real world
doi: 10.1691/ph.2020.0352 (pp. 284-287)

Review

Zhang W, Zhang P, Wang G, Cheng W, Chen J, Zhang X: Recent advances of therapeutic targets and potential drugs of COVID-19
doi: 10.1691/ph.2020.0431 (pp. 161-163)

Original Articles

Maree S, du Preez JL, du Plessis LH, du Plessis J, Gerber M: A novel HPLC method developed and validated for the detection and quantification of atorvastatin, fluvastatin, pitavastatin and pravastatin during transdermal delivery studies
doi: 10.1691/ph.2020.0007 (pp. 164-166)

Pajaziti B, Petkovska R, Andrási M, Nebija D: Application of the capillary zone electrophoresis (CZE) and capillary gel electrophoresis (CGE) for the separation of human insulin, insulin lispro and their degradation products
doi: 10.1691/ph.2020.9188 (pp. 167-171)

Ezquer-Garin C, Ferriols-Lisart R, Martinez-López LM, Sangrador-Pelluz C, Nicolás-Picó J, Alós-Almiñana M: Stability of tedizolid phosphate-sodium rifampicin and tedizolid phosphate-meropenem admixtures in intravenous infusion bags stored at different temperatures
doi: 10.1691/ph.2020.9155 (pp. 172-176)

Isagawa S, Shiohira H, Hokama N, Nitta H, Yoshida T, Masamoto H, Aoki Y, Nakamura K: Measurement of zinc concentration in blood and breast milk of a Wilson’s disease patient taking zinc acetate
doi: 10.1691/ph.2020.9765 (pp. 177-178)

Miyashiro CA, Bernegossi J, Bonifácio BV, de Toledo LG, Ramos MAS, Bauab TM, Chorilli M: Development and characterization of a novel liquid crystalline system containing sodium alginate for incorporation of trans-resveratrol intended for treatment of buccal candidiasis
doi: 10.1691/ph.2020.9165 (pp. 179-185)

Yanjie Qin, Nanxi Wang, Fen Chen, Xuemei Han, Ying Zhu, Ying Rang, Xuejia Zhai, Yongning Lu: Effects of cyclosporine A on the pharmacokinetics and toxicities of irinotecan mediated by UGT1A1 in vitro and in vivo
doi: 10.1691/ph.2020.0316 (pp. 186-190)

Ishida T, Morisawa S, Iizuka M, Fujita H, Jobu K, Morita Y, Miyamura M: Juzentaihoto extract suppresses adipocyte hypertrophy and improves hyperglycemia in KKAy mice
doi: 10.1691/ph.2020.9950 (pp. 191-194)

Yan-Yang Jin, Si-Qiao Tong, Ming Tong: Erdafitinib exerts the anticancer effect on urothelial carcinoma via induction of autophagy
doi: 10.1691/ph.2020.9911 (pp. 195-197)

Congcong Yu, Liuliu Pan, Guangbao Wang, Ziyao Cai, Yancan Zhou, Xuyong Zheng, Ce Chen, Xiaodan Zhang: Silybin enhances the blood concentration of brexpiprazole in rats by downregulating expression of CYP3A4 and CYP2D6
doi: 10.1691/ph.2020.9935 (pp. 198-200)

Meng-Jiao Du, Jian-Ping Chen, Bo-Wen Lian, Wen-Jie Mei, Jia-Xian Yu, Li-Shi Chen, Shan-Bin Deng, Yan-Mei Zhong, Chu-Qin Yu: Cardioprotective effects of timosaponin B-ll isolated from Anemarrhena rhizome in a zebrafish model
doi: 10.1691/ph.2020.9869 (pp. 201-204)

Suzuki K, Sato Y, Nakahara R, Tatsuta R, Tanaka R, Itoh H: Venous thromboembolisms and rheology in ovarian cancer patients after postoperative adjuvant paclitaxel and carboplatin therapy
doi: 10.1691/ph.2020.9908 (pp. 205-207)

Li LY, Ma L, Dong WL: Total glucosides of paeony (Paeonia lactiflora) alleviates blood-brain barrier disruption and cerebral ischemia/reperfusion injury in rats via suppressing inflammation and apoptosis
doi: 10.1691/ph.2020.0324 (pp. 208-212)

Yifeng Ni, Hao Zhang, Zhi Li, Zubing Li: Connective tissue growth factor (CCN2) inhibits TNF-α-induced apoptosis by enhancing autophagy through the Akt and Erk pathways in osteoblasts
doi: 10.1691/ph.2020.0336 (pp. 213-217)

Yamashita K, Ogihara T, Hayashi M, Nakagawa T, Ishizaki Y, Kume M, Yano I, Niigata R, Hiraoka J, Yasui H, Nakamura T: Association between dexamethasone treatment and alterations in serum concentrations of trace metals
doi: 10.1691/ph.2020.0341 (pp. 218-222)

Review

Di Liu, Yun-Zhao Li, Hui Wu, Jun Yang, Jian Yang, Jia-Wang Ding, Jing Zhang, Zhi-Xing Fan, Chao-Jun Yang: Duration of dual antiplatelet therapy after percutaneous coronary intervention with implantation of second-generation drug-eluting stent: A meta-analysis of randomized controlled trials
doi: 10.1691/ph.2020.0301 (pp. 113-117)

Original Articles

Zengjun Wang, Zhuowei Zhao, Nauman Rahim Khan, Zhen Hua, Junyi Huo, Yanhui Li: Microwave assisted chitosan-polyethylene glycol hydrogel membrane synthesis of curcumin for open incision wound healing
doi: 10.1691/ph.2020.9179 (pp. 118-123)

Tianyu Chen, Tianqiang Wu, Ningxi Li, Yichun Jiang, Huanli Yin, Min Wu: Simulation-based comparison of Biopharmaceutics Classification System and drug structure
doi: 10.1691/ph.2020.9874 (pp. 124-130)

Qiying Shen, Huan Shu, Xiaoling Xu, Gaofeng Shu, Yongzhong Du, Xiaoying Ying: Tofacitinib citrate-based liposomes for effective treatment of rheumatoid arthritis
doi: 10.1691/ph.2020.9154 (pp. 131-135)

Roosendaal J, Venekamp N, Lucas L, Rosing H, Beijnen JH: Development and validation of an LC-MS/MS method for the quantification of imatinib and imatinib-d8 in human plasma for the support of an absolute bioavailability microdose trial
doi: 10.1691/ph.2020.9150 (pp. 136-141)

Miao Li, Shu-Mei Wang, Wan-Shui Wu, Dan Yan, Le-Ping Zhang, Hu-Yong Zheng: Frequency distribution of five SNPs in human GGH gene and their effects on clinical outcomes of Chinese pediatric patients with acute lymphoblastic leukemia
doi: 10.1691/ph.2020.9932 (pp. 142-146)

Yi-Zhen Tian, Ya-Peng Liu, San-Chun Tian, Su-Yin Ge, Yong-Jie Wu, Bao-Lai Zhang: Antitumor activity of ginsenoside Rd in gastric cancer via up-regulation of Caspase-3 and Caspase 9
doi: 10.1691/ph.2020.9931 (pp. 147-150)

Niinomi I, Hosohata K, Oyama S, Inada A, Wakabayashi T, Iwanaga K: Evaluation of adverse events associated with filgrastim originator and biosimilar using a spontaneous reporting system database
doi: 10.1691/ph.2020.9189 (pp. 151-153)

Usami E, Kimura M, Takenaka S, Kanda T, Teramachi H, Yoshimura T: Continuity and efficacy of real-world use of azacitidine
doi: 10.1691/ph.2020.9905 (pp. 154-158)

Letter to the editor

Yaoub, BM: COVID-19 vaccination clinical trials should consider multiple doses of BCG
doi: 10.1691/ph.2020.044 (p. 159)

Reviews

Ruqiao L, Yueli C, Xuelan Z, Huifen L, Xin Z, Danjie Z, Le S, Yanxue Z: Rhizoma Atractylodis macrocephalae: a review of photochemistry, pharmacokinetics and pharmacology
doi: 10.1691/ph.2020.9738 (pp. 42-55)

Rashid ZA, Al-Tabakha MM, Alomar MJ: Community pharmacist’s’ knowledge and practice toward oral isotretinoin prescription: a systemic review
doi: 10.1691/ph.2020.9891 (pp. 56-60)

Original Articles

Georgieva Y, Kassarova M, Kokova V, Apostolova E, Pilicheva B: Taste masking of enalapril maleate by microencapsulation in Eudragit EPO^® microparticles
doi: 10.1691/ph.2020.9123 (pp. 61-69)

Pala Kara Z, Ozturk D, Ozturk N, Orman MN, Baktir G, Okyar A: Effects of atorvastatin on talinolol absorption: A potential drug-drug interaction
doi: 10.1691/ph.2020.9904 (pp. 70-74)

Cavalcante Loureiro K, Carvalho Barbosa T, Nery M, Vinicius Chaud M, Ferreira da Silva C, Nalone Andrade L, Bani Corrêa C, Jaguer A, Ferreira Padilha F, Cordeiro Cardoso J, Souto E, Severino P: Antibacterial activity of chitosan/collagen membranes containing red propolis extract
doi: 10.1691/ph.2020.9050 (pp. 75-81)

Hanaoka S, Endo A, Hayashi H, Hirai T, Seki T: Histamine-2 receptor antagonists (H₂RA) may negatively impact ADL assessment in patients on a convalescent rehabilitation ward
doi: 10.1691/ph.2020.9858 (pp. 82-89)

Qunli Meng, Caixa Ye, Yaqin Lu: miR-181c regulates ischemia/reperfusion injury-induced neuronal cell death by regulating c-Fos signaling
doi: 10.1691/ph.2020.9856 (pp. 90-93)

Xing Wang, Leyi Li, Sinan Pei, Qian Zhu, Feihong Chen: Disruption of SSBs repair to combat platinum resistance via the JWA-targeted Pt(IV) prodrug conjugated with a wogonin derivative
doi: 10.1691/ph.2020.9815 (pp. 94-101)

Ma L, Li LY, Zhao TL: Anti-inflammatory effects of ginsenoside Rg3 on the hypertrophic scar formation via the NF-κB signaling pathway in rabbit ears
doi: 10.1691/ph.2020.9852 (pp. 102-106)

Nari Lee, You Chul Chung, Yun Beom Kim, Sung-Min Park, Bong Seok Kim, Chang-Gu Hyun: 7,8-Dimethoxycoumarin stimulates melanogenesis via MAPKs mediated MITF upregulation
doi: 10.1691/ph.2020.9735 (pp. 107-111)

Original Articles

Ikeuchi-Takahashi Y, Ito S, Itokawa A, Ota M, Onuki Y, Hidaka S, Onishi H: Preparation and evaluation of orally disintegrating tablets containing taste masked microparticles of acetaminophen
doi: 10.1691/ph.2020.9126 (pp. 2-6)

Patlolla VGR, Holbrook WP, Gizurarson S, Kristmundsdottir Þ: Evaluation of in vitro mucoadhesiveness and texture profile analysis of doxycycline in situ hydrogels
doi: 10.1691/ph.2020.9122 (pp. 7-12)

Choi I, Park SY, Lee SW, Kang Z, Jin YS, Kim IW: Dissolution enhancement of sorafenib tosylate by co-milling with tetradecanol post-extracted using supercritical carbon dioxide
doi: 10.1691/ph.2020.9120 (pp. 13-17)

Mengying Li, Dengke Yin, Jiacheng Li, Fuping Shao, Qingqing Zhang, Qianqian Jiang, Mengmeng Zhang, Ye Yang: Rosmarinic acid, the active component of Salvia miltiorrhizae, improves gliquidone transport by regulating the expression and function of P-gp and BCRP in Caco-2 cells
doi: 10.1691/ph.2020.9754 (pp. 18-22)

Hang Jing, Guo Yi-Jia, Song Bai-Li, Lin Ya-Peng, Zhang Yu-Qiao, Geng Cong,
Hao Jun-Li, Zou Jian-Jun, Yang Jie: Effect of antiplatelet pretreatment on platelet aggregation and clinical outcomes in acute ischemic stroke patients treated with recombinant tissue-type plasminogen activator
doi: 10.1691/ph.2020.9826 (pp. 23-26)

Nguyen MTH, Ott JJ, Caputo M, Keller-Stanislawski B, Klett-Tammen CJ, Linnig S, Mentzer D, Krause G: User preferences for a mobile application to report adverse events following vaccination
doi: 10.1691/ph.2020.9734 (pp. 27-31)

Ying Xue, Meizi Zeng, Yi Zheng, Lu Wang, Song Cao, Chujun Wu, Mimi Tang, Shao Liu: Gender difference in vitamin A levels in first-episode drug-naïve depression patients: a case-control and 24-weeks follow-up study
doi: 10.1691/ph.2020.9829 (pp. 32-35)

Xiaofeng Zhang, Zhiqiang Lu, Abdul KSM, Changping Ma, Keai Sinn Tan, Jovanović A, Wen Tan: Isosteviol sodium protects heart embryonic H9c2 cells against oxidative stress by activating Akt/GSK-3β signaling pathway
doi: 10.1691/ph.2020.9851 (pp. 36-40)

Review

Shasha Guo, Xiaozhi Xi, Jia Li: Notoginsenoside R1: a systematic review of its pharmacological properties
doi: 10.1691/ph.2019.9534 (pp. 641-647)

Original Articles

Makowska A, Wolff L, Sączewski F, Bednarski PJ, Kornicka A: Synthesis and cytotoxic evaluation of benzoxazole/benzothiazole-2-imino-coumarin hybrids and their coumarin analogues as potential anticancer agents
doi: 10.1691/ph.2019.9664 (pp. 648-657)

Marais S, du Preez JL, du Plessis LH, du Plessis J, Gerber M: Determination of lovastatin, mevastatin, rosuvastatin and simvastatin with HPLC by means of gradient elution
doi: 10.1691/ph.2019.8192 (pp. 658-660)

Tanaka Y, Matsubara R, Furukawa K, Satonaka S, Kasaoka S: The influence of viscosity-enhancing agents on oral absorption of drugs
doi: 10.1691/ph.2019.9097 (pp. 661-664)

Ré ACS, Ferreira MP, Freitas O, Aires CP: Antimicrobial effect of a local release system containing metronidazole against a Porphyromonas gingivalis biofilm
doi: 10.1691/ph.2019.8241 (pp. 665-666)

Shebeko SK, Zupanets IA, Popov OS: N-Acetylglucosamine is the most effective glucosamine derivative for the treatment of membranous nephropathy in rats
doi: 10.1691/ph.2019.9733 (pp. 667-670)

Shu-Mei Wang, Miao Li, Wan-Shui Wu, Lu-Lu Sun, Dan Yan: The role of transcription factor Sp1 in the regulation of gamma-glutamyl hydrolase gene expression by the rs3758149 polymorphism in CEM/C1 cells
doi: 10.1691/ph.2019.9689 (pp. 671-674)

Zhengping Wu, Chung-Yi Chen, Chiu-Li Kao, Yinjie Jiang, Chi-Ming Liu: Docosahexaenoic acid inhibits lipopolysaccharide-induced metastatic activities by decreasing inflammation on prostate cancer cell
doi: 10.1691/ph.2019.9686 (pp. 675-679)

Hu Cai, Liyan Gong, Jie Liu, Qinfei Zhou, Zengguang Zheng: Diosgenin inhibitis tumor angiogenesis through regulating GRP78-mediated HIF-1α and VEGF/VEGFR signaling pathways
doi: 10.1691/ph.2019.9526 (pp. 680-684)

Xiangdong Li, Chunlei Li, Peiyu Zhou, Shaohua Chen: Inhibitory effect of icaritin on proliferation, migration, and invasion of human nasopharyngeal carcinoma cell CNE2 by regulating STAT3 activation
doi: 10.1691/ph.2019.9632 (pp. 685-687)

Jingrui Liu, Xiaojiao Li, Hong Zhang, Guiling Chen, Hong Chen, Yue Hu, Junqi Niu, Yanhua Ding:
Safety, pharmacokinetics and efficacy of donafenib in treating advanced hepatocellular carcinoma: report from a phase 1b trial
doi: 10.1691/ph.2019.9626 (pp. 688-693)

Yu Zhang, Hai Wang: Efficacy of montelukast sodium chewable tablets combined with inhaled budesonide in treating pediatric asthma and its effect on inflammatory factors
doi: 10.1691/ph.2019.9582 (pp. 694-697)

Wei You, Zhiming Wu, Fei Ye, Xiangqi Wu: Ginkgolide A protects adverse cardiac remodeling through enhancing antioxidation and nitric oxide utilization in mice with pressure overload
doi: 10.1691/ph.2019.9615 (pp. 698-702)

Original Articles

Qiaobei Pan, Jing Zhang, Xiang Li, Xing Han, Qian Zou, Peng Zhang, Ying Luo, Yi Jin: Preparation and pharmacokinetics of bifunctional epirubicin-loaded micelles
doi: 10.1691/ph.2019.9059 (pp. 577-582)

Jing Zhao, Jinhai Shen, Meiyu Gan, Cuiting Huang, Qihua You: Compatibility of ticagrelor with pharmaceutical excipients studied with thermal and spectroscopic techniques
doi: 10.1691/ph.2019.9070 (pp. 583-589)

Jin Wang, Hai-Hong Zhang, Fengxi Liu, Yu-Ping Zhang, Yong-Ming Zhao: Preparation, characterization and antimicrobial activity of inclusion complexes of Myristica fragrans Hott. essential oil in β-cyclodextrins
doi: 10.1691/ph.2019.9061 (pp. 590-594)

Kuchta K, Thomsen M, Scior T, Schmidt M: Interaction with St. John’s wort due to exposure with blackcurrant aroma? How not to present a case report of an adverse event
doi: 10.1691/ph.2019.9491 (pp. 595-597)

Yang Zhao, Xiangsheng Li, Zhenzhen Xu, Lifang Hao, Yanfen Zhang, Zhongcheng Liu: Pl3K-AKT-mTOR signaling pathway: the intersection of allergic asthma and cataract
doi: 10.1691/ph.2019.9080 (pp. 598-600)

Zhi-Qiang Li, Xiu-Ying Huang, Chun-Yan Hu, Zhong-Sheng Zhu, Yang Chen, Ming Gong: Geniposide protects against ox-LDL-induced foam cell formation through inhibition of MAPKs and NF-κB signaling pathways
doi: 10.1691/ph.2019.9506 (pp. 601-605)

Chen ML, Gou JM, Meng XL, Chen CL, Liu XN: Cepharanthine, a bisbenzylisoquinoline alkaloid, inhibits lipopolysaccharide-induced microglial activation
doi: 10.1691/ph.2019.9562 (pp. 606-610)

Uwai Y, Tsuduki M, Kawasaki T, Nabekura T: Effect of acetazolamide on lithium reabsorption and lithium-induced GSK3β phosphorylation in rat kidney
doi: 10.1691/ph.2019.9060 (pp. 611-613)

Yamashita T, Kamada H, Kanasaki S, Nagano K, Inoue M, Higashisaka K, Yoshioka Y, Tsutsumi Y, Tsunoda S: Ephrin type-A receptor 2 on tumor-derived exosomes enhances angiogenesis through the activation of MAPK signaling
doi: 10.1691/ph.2019.9474 (pp. 614-619)

Hirose C, Iihara H, Funaguchi N, Endo J, Ito F, Yanase K, Kaito D, Sasaki Y, Gomyo T, Sakai C, Ohno Y, Suzuki A: Prophylactic effect of rikkunshito, an herbal medicine, for chemotherapy-induced nausea in thoracic cancer patients receiving carboplatin-based chemotherapy
doi: 10.1691/ph.2019.9497 (pp. 620-624)

Dvořáčová E, Rychlíčková J, Pávek P, Hojný, Vlček J: Analysis and management of drug related problems on a nephrology ward from a pharmacist´s point of view
doi: 10.1691/ph.2019.9568 (pp. 625-629)

Ino Y, Shimauchi A, Tachi T, Noguchi Y, Sakai C, Iguchi K, Kano A, Teramachi H: Community pharmacy-level factors associated with medical and nursing home facility collaboration in Japan
doi: 10.1691/ph.2019.9489 (pp. 630-638)

Review

Xiaowei C, Wei W, Hong G, Hui C, Xiaofei Z, Haonan W, Yumeng W, Xuelan Z, Chunchao H: Review of Polygonatum sibiricum: A new natural cosmetic ingredient
doi: 10.1691/ph.2019.9438 (pp. 513-519)

Original Articles

Jina Yang, Jadhav PD, Reaney MJT, Sammynaiken R, Jian Yang: A novel formulation significantly increases the cytotoxicity of flaxseed orbitides (linusorbs) LOB3 and LOB2 towards human breast cancer MDA-MB-231 cells
doi: 10.1691/ph.2019.9055 (pp. 520-522)

Zilin Feng, Mengting Li, Wenxi Wang: Improvement of dissolution and tabletability of carbamazepine solid dispersions with high drug loading prepared by hot-melt extrusion
doi: 10.1691/ph.2019.9008 (pp. 523-528)

You Chul Chung, Seung-Young Kim, Chang-Gu Hyun: 8-Methoxycoumarin enhances melanogenesis via the MAPKase signaling pathway
doi: 10.1691/ph.2019.9553 (pp. 529-535)

Behnisch-Cornwell S, Laubenstein G, Bednarski PJ: Studies of the inhibitory activities of tiopronin and mercaptosuccinic acid on glutathione peroxidase and their cytotoxic and antioxidant properties
doi: 10.1691/ph.2019.9472 (pp. 536-542)

Bin Zhang, Tiankui Qiao, Caixia Gao: Effects and mechanism of ensartinib (X-396) on the adhesion and metastasis of non-small cell lung cancer cells
doi: 10.1691/ph.2019.9461 (pp. 543-546)

Zongdan Jiang, Zhibing Wang, Zhi Wang, Chao Li, Zhenyu Zhang, Weihao Sun: The activation of high mobility group Box1 and toll-like receptor 4 is involved in clopidogrel-induced gastric injury through p38 MAPK
doi: 10.1691/ph.2019.9446 (pp. 547-552)

Yutong Huang, Taoming Huang, Xiaonuo Zhen, Yali Li, Mingguang Mo, Deyong Ye, Nengneng Cheng: A selective sphingomyelin synthase 2 inhibitor ameliorates diet induced insulin resistance via the IRS-1/Akt/GSK-3β signaling pathway
doi: 10.1691/ph.2019.9310 (pp. 553-558)

Urashima Y, Urashima K, Ohnishi M, Matsushita K, Suzuki K, Kurachi K, Nishihara M, Katsumata T, Myotoku M, Ikeda K, Hirotani Y: Interaction between phenytoin and enteral nutrients and its influence on gastrointestinal absorption
doi: 10.1691/ph.2019.9532 (pp. 559-562)

Blaess M, Wenzel F, Csuk R, Deigner HP: Topical use of amitriptyline and linoleic acid to restore ceramide rheostat in atopic dermatitis lesions – a case report
doi: 10.1691/ph.2019.9484 (pp. 563-565)

Uchida M, Nakamura T, Watanabe H, Kato K, Miyamoto T, Akashi K, Masuda S: Usefulness of medication instruction sheets for sharing information on cancer chemotherapy within the health care team
doi: 10.1691/ph.2019.9467 (pp. 566-569)

Noguchi Y, Nagasawa H, Tachi T, Tsuchiya T, Teramachi H: Signal detection of oral drug-induced dementia in chronic kidney disease patients using association rule mining and Bayesian confidence propagation neural network
doi: 10.1691/ph.2019.9426 (pp. 570-574)

Review

Arends RJ, Wang D, Buurman M, Luten J, Koper NP, Wolf C, Scheren M: Comparison of Copaxone^® and Synthon’s therapeutically equivalent glatiramer acetate
doi: 10.1691/ph.2019.9515 (pp. 449-461)

Original Articles

 Htwe MM, Teanpaisan R, Khongkow P, Amnuaikit T: Liposomes of probiotic’s lyophilized cell free supernatant; a potential cosmeceutical product
doi: 10.1691/ph.2019.9030 (pp. 462-466)

Szczepanska M, Sznitowska M: Comparison of the coating process and in vitro dissolution of 3 mm gastro-resistant minitablets and 5 mm gastro-resistant tablets with pantoprazole
doi: 10.1691/ph.2019.8180 (pp. 467-470)

Jie Zhao, Ran Meng, Qiang Yao, Hui Wang, Jingxiu Niu, Yu Cui, Songlin Chen, Yinshuang Bai: Long non-coding RNA HEIH promotes breast cancer development via negative modulation of microRNA-200b
doi: 10.1691/ph.2019.9428 (pp. 471-476)

Pang Tao, Zhao Jing, Gao Shou-Hong, Piao Shu-Juan, Jiao Jian-Peng, Lu Wen-Quan, Chen Wan-Sheng: Effects of leptin on norepinephrine in acute ischemic stroke
doi: 10.1691/ph.2019.9379 (pp. 477-480)

Ji Wu, Fangfang Yang, Xinju Li, Tao Wu, Li Liu, Hongping Song: Swertiamarin protects neuronal cells from oxygen glucose deprivation/reoxygenation via TLR4/PARP1/NFκB pathway
doi: 10.1691/ph.2019.9369 (pp. 481-484)

Agbo E, Li MX, Wang YQ, Saahene RO, Massaro J, Tian GZ: Hexarelin protects cardiac H9C2 cells from angiotensin II-induced hypertrophy via the regulation of autophagy
doi: 10.1691/ph.2019.9324 (pp. 485-491)

Xiaona Shao, Chen Chen, Chunsheng Miao, Xiaoyan Yu, Xiangjun Li, Jianan Geng, Dongyan Fan, Xueyuan Lin, Zhen Chen, Yan Shi: Expression analysis of microRNAs and their target genes during experimental diabetic renal lesions in rats administered with ginsenoside Rb1 and trigonelline
doi: 10.1691/ph.2019.8903 (pp. 492-498)

Uchida M, Hada M, Yamada M, Inma D, Ariyoshi S, Aoki K, Inoue S, Shimazoe T, Mitsuiki K, Haraguchi T: Impact of a systematic education model for palliative care in cancer
doi: 10.1691/ph.2019.9417 (pp. 499-504)

Lauze S, Mauriņa B, Šidlovska V: Pharmacy in Latvia during the first Soviet occupation (1940-1941)
doi: 10.1691/ph.2019.8232 (pp. 505-510)

Reviews

Helmstädter A: Traditional use and scientific investigations of the medicinal plant Simaba cedron Planch.
doi: 10.1691/ph.2019.9490 (pp. 385-389)

Shichun Zhong, Caijun Wang, Renhui Gao, Shuang Shu, Chengjun Shu: Association between DEFB1 polymorphisms and periodontitis: a meta-analysis
doi: 10.1691/ph.2019.9459 (pp. 390-396)

Original Articles

Qimeng Fan, Wenlong Liu, Yantao Yang, Jin Zhou, Yu Tang, Meifeng Xiao, Xue Pan, Yiqun Zhou, Kaiwen Deng, Fuyuan He: A new similarity method for assessment of pharmacokinetic interaction between flucloxacillin and midazolam
doi: 10.1691/ph.2019.9016 (pp. 397-405)

López-Barrera LD, Díaz-Torres R, López Macay A, López-Reyes AG, Piña Olmos S, Ramírez-Noguera P: Oxidative stress modulation induced by chitosan-glutathione nanoparticles in chondrocytes
doi: 10.1691/ph.2019.8166 (pp. 406-411)

Wen Zhou, Gaole Yuan, Qingsong Wang: Vitamin D attenuates lipopolysaccharide-induced inflammatory response in endothelial cells through inhibition of Pl3K/Akt/NF-κB signaling pathway
doi: 10.1691/ph.2019.9373 (pp. 412-417)

Hong Li, Changhu Dong, Yanning Tian, Xiang Li, Bing Wang, Dongzhi Zhai, Yingying Bai, Xu Chao: Knockdown of diacylglycerol kinase zeta (DGKZ) induces apoptosis and G2/M phase arrest in human acute myeloid leukemia HL-60 cells through MAPK/survivin/caspase pathway
doi: 10.1691/ph.2019.9386 (pp. 418-422)

Sanming Wang, Xiaohang Chen, Zhenwei Zhang, Zeyu Wu: MicroRNA-1225-5p inhibits the development and progression of thyroid cancer via targeting sirtuin 3
doi: 10.1691/ph.2019.9411 (pp. 423-427)

Peng Wang, Qian Tan: Early treatment of recombinant Akt protects the retina from oxygen-induced injury in mice
doi: 10.1691/ph.2019.9416 (pp. 428-431)

Yao Jin, Shuhong Zhang, Jianmei Pan, Meng Yue, Guoshan Zhang, Dongxue Yao, Qiuzhi Wang: Comparison of efficacy and safety of ilaprazole and esomeprazole both in initial treatment regimen and retreatment regimen of Helicobacter pylori infection in chronic gastritis
doi: 10.1691/ph.2019.9349 (pp. 432-438)

Tanaka K, Tachi T, Hori A, Osawa T, Nagaya K, Makino T, Inoue S, Yasuda M, Mizui T, Nakada T, Goto C, Teramachi H: Cost utility analysis of pharmacist counseling care for breast cancer chemotherapy outpatients
doi: 10.1691/ph.2019.9327 (pp. 439-442)

Petroianu GA: Veilchenduft, ectopic olfactory receptors and endogenous volatile compounds: Who was Paul Krüger (1859-1916)?
doi: 10.1691/ph.2019.9013 (pp. 443-446)

Original Articles

Kun-Jie Xiao, Wei-Qiong Zuo, Ying Xu, Xin Tao, Luo-Ting Yu, Ning-Yu Wang: Discovery and structure-resistance relationship study of new thieno[2,3-b] pyridine HCV NS4B inhibitors
doi: 10.1691/ph.2019.8960 (pp. 321-325)

Basholli-Salihu M, Kryeziu TL, Nebija D, Salar-Behzadi S, Viernstein H, Mueller M: Prebiotics as excipients for enhancement of stability and functionality of Bifidobacterium longum ssp. infantis with potential application as symbiotics in food and pharmaceuticals
doi: 10.1691/ph.2019.9007 (pp. 326-333)

Grela KP, Bagińska I, Burak J, Marciniak DM, Karolewicz B: Natural gums as viscosity-enhancers in Pluronic^® F-127 thermogelling solutions
doi: 10.1691/ph.2019.8187 (pp. 334-339)

Hussain H, Ziegler J, Mrestani Y, Neubert RHH: Studies of the corneocytary pathway across the Stratum corneum. Part I: Diffusion of amino acids into the isolated corneocytes
doi: 10.1691/ph.2019.8098 (pp. 340-344)

Nan Jin, Sung Min Pyo, Keck CM, Müller RH: Maximum loaded amorphous azithromycin produced using the wetness impregnation method with fractional steps for dermal prophylaxis against Lyme disease
doi: 10.1691/ph.2019.8175 (pp. 345-349)

Aucamp M, Liebenberg W, Okaecwe T, Geldenhuys M, Stieger N: Compatibility between four anti-TB drugs and tablet excipients determined by microcalorimetry
doi: 10.1691/ph.2019.8189 (pp. 350-351)

Chen ZH, Zhou H, Wang S, Li G, Zhang J, Wang F, Li C, Qiao RZ: An isolated method and assignment for critical impurities in semi-synthetic process of arbekacin sulfate
doi: 10.1691/ph.2019.8242 (pp. 352-356)

Curti C, Harti Souab K, Lamy E, Mathias F, Bornet C, Guinard B, Fersing C, Primas N, Albanèse J, Vanelle P: Stability studies of antipyocyanic beta-lactam antibiotics used in continuous infusion
doi: 10.1691/ph.2019.8215 (pp. 357-362)

Gongsheng Jin, Yonghong Liu, Peiquan Xu, Gongsheng Jin: Induction of necroptosis in human breast cancer drug-resistant cells by SMAC analog LCL161 after caspase inhibition requires RIP3
doi: 10.1691/ph.2019.9307 (pp. 363-368)

Ling Liu, Jianmin Li, Ruzhu Wang, Yebao Wang, Guoyu Wang: MicroRNA-298 exacerbates myocardial ischemic injury via targeting cyclin D1
doi: 10.1691/ph.2019.9303 (pp. 369-373)

Esaki H, Tachi T, Goto C, Noguchi Y, Tanaka K, Aoyama S, Yasuda M, Mizui T, Yamamura M, Teramachi H: Relationship between initial renal function and the inhibitory effect of dipeptidyl peptidase-4 inhibitor treatment on renal function decline
doi: 10.1691/ph.2019.8973 (pp. 374-382)

Review

Ying Dong, Yi Wang, Rui-Lian Ma, Zhong-Chao Cao, Zhi-Chun Huang, Xian-Hua Ren, Xiao-Lei Liu, Jian-Jun Sun: Triple versus dual oral antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention: a systematic review and meta-analysis
doi: 10.1691/ph.2019.8798 (pp. 257-264)

Original Articles

Jing Jiang, Xiaoqiang Zhao, Tianyu Niu, Haiyan Yan, Yinghong Li, Yuhuan Li, Danqing Song, Sheng Tang, Jianguo Xing: Construction and synthesis of tricyclic matrinic derivatives against influenza A virus by privileged structure strategy
doi: 10.1691/ph.2019.8968 (pp. 265-269)

Viljoen FP, du Preez JL, Petzer A, Wessels JC, Petzer J, Aucamp ME: Development and validation of a HPLC electrochemical detection method to measure COMT activity as a tool in drug development
doi: 10.1691/ph.2019.8218 (pp. 270-276)

Nan Jin, Sung Min Pyo, Keck CM, Müller RH: Azithromycin nanocrystals for dermal prevention of tick bite infections
doi: 10.1691/ph.2019.8169 (pp. 277-285)

Yamashita S, Iguchi K, Noguchi Y, Sakai C, Yokoyama S, Ino Y, Hayashi H, Teramachi H, Sako M, Sugiyama T: Color change in Perlodel^® tablets induced by LED lighting – photolysis of bromocriptine mesylate
doi: 10.1691/ph.2019.8109 (pp. 286-289)

Chengzhu Wu, Meijia Gao, Lin Shen, Bohan Li, Xiangjian Bai, Jiahui Gui, Hongmei Li, Qiang Huo, Tao Ma: Miconazole triggers various forms of cell death in human breast cancer MDA-MB-231 cells
doi: 10.1691/ph.2019.8812 (pp. 290-294)

Lei Wang, Shanshan Zhao, Mingxin Yu: LncRNA NR2F1-AS1 involves in the progression of endometrial cancer by sponging miR-363 to target SOX4
doi: 10.1691/ph.2019.8905 (pp. 295-300)

Hengjuan Lv, Guibo Liu, Kun Li, Mingqiu Li, Dawei Zhang: Angiogenin regulates epithelial-mesenchymal transition of hepatocellular carcinoma through upregulation of HMGA2
doi: 10.1691/ph.2019.8943 (pp. 301-304)

Noguchi Y, Toda Y, Esaki H, Matsuyama T, Tachi T, Tsuchiya T, Teramachi H: Association between dipeptidyl peptidase-4 inhibitors and autoimmune disorders: Data mining of the spontaneous reporting system in Japan
doi: 10.1691/ph.2019.8972 (pp. 305-309)

Momo K, Shimano M, Kanezaki Y, Minagawa A, Takagi A, Seino T, Koinuma M: Assessment of “look-alike” packaging designs related to medication errors using information technology
doi: 10.1691/ph.2019.8924 (pp. 310-312)

Schiek S, Seichter SJ, Moritz K, Hertel G, Ghanem M, Bertsche T: A prospective follow-up study on the role of clinical pharmacists in sustainably optimized pain measurement and pain therapy consequences
doi: 10.1691/ph.2019.9304 (pp. 313-318)

Reviews

Stücker M, Rabe E, Meyer K. Ottillinger B, Schütt T: Therapeutic approach to chronic venous insufficiency – clinical benefits of red-vine-leaf-extract AS 195 (Antistax^®)
doi: 10.1691/ph.2019.9326 (pp. 193-200)

Cong Wang, Liqin Li, Hongyu Xu, Hongliu Lv, Houzhong Zhang: Effect of desflurane-remifentanil or sevoflurane-remifentanil on early recovery in elderly patients: a meta-analysis of randomized controlled trials
doi: 10.1691/ph.2019.8935 (pp. 201-205)

Original Articles

Viljoen FP, du Preez JL, Wessels JC, Aucamp ME, Meyer LCR, Pohlin F: An HPLC-DAD validated method for the detection and quantification of cortisol, corticosterone and melatonin in plasma samples of two different animal species
doi: 10.1691/ph.2019.8225 (pp. 206-211)

Gomes TF, Gualberto FCM, Perasoli FB, Andrade FP, Moura SAL, Da Silva GR: Intra-articular leflunomide poly(ε-caprolactone) implants to treat synovitis in rheumatoid arthritis
doi: 10.1691/ph.2019.8223 (pp. 212-220)

Tacchi Campos MS, Fialho SL, Pereira BG, Yoshida MI, Mussel WN, Cunha Junior AS, Oliveira MA: Development and chemical characterization of biodegradable polymeric implants containing sirolimus for the treatment of malignant solid tumors
doi: 10.1691/ph.2019.8201 (pp. 221-226)

Saab M, Mehanna MM: Disintegration time of orally dissolving films: various methodologies and in-vitro/in-vivo correlation
doi: 10.1691/ph.2019.8231 (pp. 227-230)

Guoliang Yang, Chengqiang Wu, Lang Li, Zhiyu Zeng, Xiao Ma, Jing Wei, Chun Gui: Neuregulin-1 protects cardiac electrical conduction through downregulating matrix metalloproteinase-9 and upregulating connexin 43 in a rat myocardial infarction model
doi: 10.1691/ph.2019.8941 (pp. 231-234)

Jianping Chen, Zhenyu Xu, Changsheng Yu, Zhengqing Wu, Zhaocai Yin, Fang Fang, Bin Chen: MiR-758-3p regulates papillary thyroid cancer cell proliferation and migration by targeting TAB1
doi: 10.1691/ph.2019.8933 (pp. 235-238)

Luxin Li, Xu Lian, Zhilong Wang, Junya Zheng, Jieting Liu, Yanhui Chu, Yanjie Teng, Zhen Zhang: The dipeptidyl peptidase-4 inhibitor sitagliptin ameliorates renal injury in type 1 diabetic mice via inhibiting the TGF-β/Smad signal pathway
doi: 10.1691/ph.2019.8918 (pp. 239-242)

Hao Yu, Qun Zhong, Yali Xia, Enchun Li, Shufang Wang, Rong Ren: MicroRNA-2861 targets STAT3 and MMP2 to regulate the proliferation and apoptosis of ectopic endometrial cells in endometriosis
doi: 10.1691/ph.2019.8881 (pp. 243-249)

Uchida M, Nakamura T, Shima T, Mori Y, Yoshimoto G, Kato K, Shimokawa M, Hosohata K, Miyamoto T, Akashi K: Evaluation of the compliance with antiemetic guidelines for prevention of chemotherapy-induced nausea and vomiting in patients with hematologic malignancy
doi: 10.1691/ph.2019.8889 (pp. 250-254)

Original Articles

Franchini S, Sorbi C, Linciano P, Brasili L, Tait A: Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT_1AR antagonist
doi: 10.1691/ph.2019.8878 (pp. 131-135)

Foerster A, Neubert RHH: Dermal peptide delivery using enhancer molecules and colloidal carrier systems – part V^#: Influence of enhancers on the permeation of PKEK through snake skin
doi: 10.1691/ph.2019.8105 (pp. 136-141)

Liang Wei, Cheng Yang, Ke-Qin Li, Chun-Long Zhong, Zhi-Yang Sun: 3-Aminobenzamide protects against cerebral artery injury and inflammation in rats with intracranial aneurysms
doi: 10.1691/ph.2019.8911 (pp. 142-146)

Kitano Y, Wakimoto S, Tamura S, Kubota K, Domon Y, Arakawa N, Saito M, Sava B, Buisson B: Effects of mirogabalin, a novel ligand for the α₂δ subunit of voltage-gated calcium channels, on N-type calcium channel currents of rat dorsal root ganglion culture neurons
doi: 10.1691/ph.2019.8833 (pp. 147-149)

Yibo Dai, Yaqi Xu, Yang Jiang, Wen Jiang, Xiaoli Liu, Chengyun Zhang: AK-968 efficiently inhibits proliferation and induces cell apoptosis in human multiple myeloma cells
doi: 10.1691/ph.2019.8914 (pp. 150-153)

An Hu, Yunfeng Zhang, Xipeng Zhao, Jian Li, Yong Ying: CBX1 is a direct target of miR-205-5p and contributes to the progression of pituitary tumor
doi: 10.1691/ph.2019.8908 (pp. 154-156)

Chengjun Yuan, Huating Wang, Zuyi Yuan: Ginsenoside Rg1 inhibits myocardial ischaemia and reperfusion injury via HIF-1α-ERK signalling pathways in a diabetic rat model
doi: 10.1691/ph.2019.8858 (pp. 157-162)

Sisi Kang, Zhuo Wang, Bin Li, Xiujuan Gao, Wenjuan He, Sisi Cao, Yue Cai, Hui Chen: Anti-tumor effects of resveratrol on malignant melanoma is associated with promoter demethylation of RUNX3 gene
doi: 10.1691/ph.2019.8838 (pp. 163-167)

Wen Zhou, Qingsong Wang: Vitamin D suppresses lipopolysaccharide-induced inflammatory response in vascular smooth muscle cells via inhibition of the p38 MAPK signaling pathway
doi: 10.1691/ph.2019.8818 (pp. 168-174)

Xiaogang Tang, Qiulong Ding, Chao Chen, Fei Chen, Xiyang Zhou, ChuJie Hong, Wensheng Pan: Micheliolide inhibits gastric cancer growth in vitro and in vivo via blockade of the IL-6/STAT3 pathway
doi: 10.1691/ph.2019.8816 (pp. 175-178)

Onah IA, Onuigbo EB, Odimegwu DC: Adjuvant effect of Vernonia amygdalina leaf extract on host immune response to hepatitis B virus subunit vaccine
doi: 10.1691/ph.2019.8920 (pp. 179-185)

Breiholz S, Griese-Mammen N, Krueger K, Schaefer M, Schulz M: Acceptance of a medication refill reminder service in German community pharmacy practice
doi: 10.1691/ph.2019.8669 (pp. 186-190)

Review

Rui Zhang, Weimei Shi, Linfu Li, Xianhua Huang, Daohua Xu, Longhuo Wu: Biological activity and health promoting effects of psoralidin
doi: 10.1691/ph.2019.8619 (pp. 67-72)

Original Articles

Wang A, Lili, Zhang, Xu Y: Synthesis and antibacterial activity of novel icariin derivatives
doi: 10.1691/ph.2019.8866 (pp. 73-78)

Pang J, Li CR, Zhao R, Nie TY, Li GQ, Lu X, Hu XX, Wang XK, Yang XY, You XF: Simplified LC-MS/MS method for quantification of IG-105, a novel tubulin ligand, and its application to the pharmacokinetic study in rats at the anticancer effective dose
doi: 10.1691/ph.2019.8157 (pp. 79-82)

Dan Liu, Qi Zhang, Jing Wang, Li Fan, Wenquan Zhu, Defu Cai: Hyaluronic acid-coated single-walled carbon nanotubes loaded with doxorubicin for the treatment of breast cancer
doi: 10.1691/ph.2019.8152 (pp. 83-90)

Witika BA, Walker RB: Development, manufacture and characterization of niosomes for the delivery of nevirapine
doi: 10.1691/ph.2019.8168 (pp. 91-96)

Główka FK, Hermann TW, Danielak D, Hermann J, Zabel M: Bioavailability of moclobemide from two formulation tablets in healthy humans
doi: 10.1691/ph.2019.8819 (pp. 97-100)

Fujing Wang, Maomao Zhu, Nan Jiang, Minghua Zhang, Liang Feng, Xiaobin Jia: Paeonol ameliorates lipopolysaccharides-induced acute lung injury by regulating TLR4/MyD88/ NF-κB signaling pathway
doi: 10.1691/ph.2019.8860 (pp. 101-106)

Shy Yang, Jin-Ping Hu, Yan Li: The involvement of blood cells in the phosphorylation of the selective sphingosine-1-phosphate receptor 1 agonist SYL-927
doi: 10.1691/ph.2019.8809 (pp. 107-110)

Wei Xiong, Shu Yang, Wanfu Zhang, Yesheng Chen, Feng Wang: MiR-761 inhibits colorectal cancer cell proliferation and invasion through targeting HDAC1
doi: 10.1691/ph.2019.8756 (pp. 111-114)

Baochang Qi, Rujun Sun, Jiesheng Rong, Zhibin Peng, Yansong Wang: Cyclic adenosine phosphate improves functional recovery after spinal cord injury via activating unfolded protein response
doi: 10.1691/ph.2019.8347 (pp. 115-119)

Yoshida T, Yoshida S, Okada H, Suzuki A, Niwa T, Suzuki K, Ohmori T, Kobayashi R, Baba H, Suzuki K: Risk factors for decreased teicoplanin trough concentrations during initial dosing in critically ill patients
doi: 10.1691/ph.2019.8731 (pp. 120-124)

Liquan Sun, Mei Zhou, Tao Liu: Association between SRD5A2 polymorphism and hypospadias: a meta-analysis
doi: 10.1691/ph.2019.8768 (pp. 125-128)

Reviews

Hongyu Li, Yanfei Jia, Yunshan Wang: Targeting HIF-1α signaling pathway for gastric cancer treatment
doi: 10.1691/ph.2019.8674 (pp. 3-7)

Ruirong Pan, Yanyan Li, Hongwen Zhou: Efficacy and safety of different doses of alirocumab in reducing low-density lipoprotein cholesterol levels: a network meta-analysis
doi: 10.1691/ph.2019.8584 (pp. 8-14)

Original Articles

Magli E, Fiorino F, Severino B, Corvino A, Perissutti E, Frecentese F, Giordano F, Saccone I, Luciano P, Zaminelli T, Santagada V, Caliendo G, de Nucci G: Synthesis of phenylpyrimidinones as guanylyl cyclase C inhibitors
doi: 10.1691/ph.2019.8775 (pp. 15-17)

Knoth H, Scriba GKE, Langnaese S, Buettner B: Differential pulse polarographic investigation of micafungin and anidulafungin using a dropping mercury electrode
doi: 10.1691/ph.2019.8680 (pp. 18-22)

Yanping Jiang, Jian Zhuang, Yanyan Lin, Xiaoyun Wang, Jianguo Chen, Fengzhen Han: Long noncoding RNA SNHG6 contributes to ventricular septal defect formation via negative regulation of miR-101 and activation of Wnt/β-catenin pathway
doi: 10.1691/ph.2019.8736 (pp. 23-28)

Fei Li, Nannan Wang, Yanlei Yang, Su Zhang, Zhe Cui, Yanfen Zhang, Zhongcheng Liu: Species-specificity in the interaction of IgE with FcεRI between humans and rats
doi: 10.1691/ph.2019.8771 (pp. 29-33)

Benavent C, García-Herrero V, Torrado C, Torrado-Santiago S: Nystatin antifungal micellar systems on endotracheal tubes: development, characterization and in vitro evaluation
doi: 10.1691/ph.2019.8138 (pp. 34-38)

Jiazhen Zhu, Jiafeng Zou, Chaofeng Mu, Wenzhi Yang, Mancang Gu, Jinmin Lin, Xinli Song, Hongyue Zheng, Fanzhu Li: Intranasal administration of pullulan-based nanoparticles for enhanced delivery of adriamycin into the brain: in vitro and in vivo evaluation
doi: 10.1691/ph.2019.8124 (pp. 39-46)

Taoxing Peng, Feng Guo, Desheng Liang, Yuan Gao, Xiuying Zhang, Suping Qiu, Jian Liu, Haijun Zhong: Improved gastrointestinal stability of solid lipid nanoparticles using comb-shaped amphiphilic inulin derivatives
doi: 10.1691/ph.2019.8140 (pp. 47-53)

Huanli Yin, Langtao Wang, Min Wu, Yuan Liu, Ningxi Li, Tianyu Chen: Cyanidin-3-O-glucoside chloride acts synergistically with luteolin to inhibit the growth of colon and breast carcinoma cells
doi: 10.1691/ph.2019.8746 (pp. 54-61)

Kobayashi S, Momo K, Yasu T, Higashino S, Kuroda S: A case of under-dosing after raltegravir formulation change in an elderly patient treated for HIV
doi: 10.1691/ph.2019.8788 (pp. 62-63)

Review

Sienkiewicz-Oleszkiewicz B, Wiela-Hojeńska A: CYP2C19 polymorphism in relation to the pharmacotherapy optimization of commonly used drugs
doi: 10.1691/ph.2018.8689 (pp.619-624)

Original Articles

Wichitnithad W, Kiatkumjorn T, Jithavech P, Thanawattanawanich P, Ratnatilaka na Bhuket P, Rojsitthisak P: A simple and sensitive HPLC-fluorescence method for the determination of moxifloxacin in human plasma and its application in a pharmacokinetic study
doi: 10.1691/ph.2018.8148 (pp. 625-629)

Handeng Lv, Enzhao Shen, Lu Luo, Yong Xu, Yaqian Pan, Kaiqi Wu, Zhicheng Xing, Faqing Ye, Yuan Zhang: An UPLC-MS/MS method for the determination of EAl045 in plasma and tissues and its application to pharmacokinetic and distribution studies in rats
doi: 10.1691/ph.2018.8123 (pp. 630-634)

Belal A: Drug likeness, targets, molecular docking and ADMET studies for some indolizine derivatives
doi: 10.1691/ph.2018.8061 (pp. 635-642)

Li-Meng, Lei-Xue: Levetiracetam inhibits endocytosis and augments short-term depression
doi: 10.1691/ph.2018.8634 (pp. 643-646)

Zhao Xinyan, Hu Zhengbang, Zhang Xuekang, Hu Qian, Wu Qiong, Liang Sisi, Fang Xinhua, Shu Shi, Liu Zhiyi: Effects of dexmedetomidine, propofol and etomidate on the intraoperative wake-up in the cerebral functional area under the guidance of entropy index
doi: 10.1691/ph.2018.8613 (pp. 647-650)

Huiyan Deng, Huaping Li, ZiYin Mo, XinYue Dai, Quan Chen, Runxiang Li, Bihua Liang, Huilan Zhu: Pterostilbene’s protective effects against photodamage caused by UVA/UVB irradiation
doi: 10.1691/ph.2018.8598 (pp. 651-658)

Domon Y, Kitano Y, Makino M: Analgesic effects of the novel α₂δ ligand mirogabalin in a rat model of spinal cord injury
doi: 10.1691/ph.2018.8550 (pp. 659-661)

Qi Feng, Peng Guo, Shengjie Kang, Feifei Zhao: High expression of TAZ/YAP promotes the progression of malignant melanoma and affects the postoperative survival of patients
doi: 10.1691/ph.2018.8499 (pp. 662-665)

Sijing Dong, Jianbo Ji, Baofang Zhang, Lingyun Hu, Xiangzhen Cui, Haina Wang: Protective effects and possible molecular mechanism of Hovenia dulcis Thunb. extract on acetaminophen-induced hepatotoxicity
doi: 10.1691/ph.2018.8650 (pp. 666-670)

Nishihara M, Morikawa N, Yokoyama S, Nishikura K, Yasuhara M, Matsuo H: Risk factors increasing blood pressure in Japanese colorectal cancer patients treated with bevacizumab
doi: 10.1691/ph.2018.8664 (pp. 671-675)

Petroianu GA, Stegmeier-Petroianu A, Lorke DE: Cleopatra: from turpentine and juniper to ionone and irone
doi: 10.1691/ph.2018.8142 (pp. 676-680)

Original Articles

Lohrer B, Bracher F: A convenient identification of carbamate-derived drug substances
doi: 10.1691/ph.2018.8092 (pp. 555-558)

Phattanawasin P, Sotanaphun U, Burana-Osot J, Piyapolrungroj N: Isolation and characterization of the acid and base degradation products of andrographolide
doi: 10.1691/ph.2018.8082 (pp. 559-562)

Viljoen FP, du Preez JL, Wessels JC, Aucamp ME: HPLC electrochemical detection and quantification of monoamines and their metabolites in rat brain tissue samples
doi: 10.1691/ph.2018.8099 (pp. 563-569)

Makoni PA, Khamanga SM, Wa Kasongo K, Walker RB: The use of experimental design for the development and validation of an HPLC-ECD method for the quantitation of efavirenz
doi: 10.1691/ph.2018.8074 (pp. 570-578)

Xianduo Sun, Xiaomin Tang, Quan Yang: An effective quantitative fingerprint method for evaluating the quality consistency of Desmodium styracifolium
doi: 10.1691/ph.2018.8590 (pp. 579-584)

Ting Li, Youran Zhang, Baihui Zhu, Chunfang Wu, Yong Chen: Telmisartan regulates the development of cerebral ischemia by alleviating endoplasmic reticulum stress
doi: 10.1691/ph.2018.8592 (pp. 585-588)

Jinxia Li, Lu Xu, Rui Sang, Yifan Yu, Bingjie Ge, Xuemei Zhang: Immunomodulatory and anti-inflammatory effects of total flavonoids of Astragalus by regulating NF-κB and MAPK signalling pathways in RAW 264.7 macrophages
doi: 10.1691/ph.2018.8633 (pp. 589-593)

Bo Wu, Xi Chen, Ying Zhou, Pingjun Hu, Dan Wu, Guodong Zheng, Yi Cai: Andrographolide inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cell line C666-1 through LKB1-AMPK-dependent signaling pathways
doi: 10.1691/ph.2018.8583 (pp. 594-597)

Tachi T, Yoshida A, Kanematsu Y, Sugita I, Noguchi Y, Osawa T, Yasuda M, Mizui T, Goto C, Teramachi H: Factors influencing the use of over-the-counter drugs and health foods/supplements
doi: 10.1691/ph.2018.8617 (pp. 598-604)

Neininger MP, Buchholz P, Kiess W, Siekmeyer M, Bertsche A, Bertsche T: Incompatibilities in paediatric intensive care – pitfalls in drug information
doi: 10.1691/ph.2018.8585 (pp. 605-608)

Tominaga Y, Aomori T, Hayakawa T, Morisky DE, Takahashi K, Mochizuki M: Relationship between medication adherence and glycemic control in Japanese patients with type 2 diabetes
doi: 10.1691/ph.2018.8587 (pp. 609-612)

Yoshida Y, Komori K, Aoki M, Sandou M, Takagi M, Uejima E: Efficacy of pegfilgrastim administration in patients with esophageal cancer treated with docetaxel, cisplatin, and 5-fluorouracil
doi: 10.1691/ph.2018.8576 (pp. 613-616)

Review

Xiaoyu Shi, Chen Liu, Baoqing Liu, Juntao Chen, Xiaoying Wu, Weihua Gong: JQ1: a novel potential therapeutic target
doi: 10.1691/ph.2018.8480 (pp. 491-493)

Original Articles

Jian-Yong Yuan, Di Zhang, Xiang-Nan Hu, Hua-jun Wang, Dong-zhi Ran, Su-Qing Shang, Zong-Jie Gan: Synthesis and characterization of four process impurities in pazopanib
doi: 10.1691/ph.2018.8538 (pp. 494-497)

Sung Chan Jeong, Dong Shik Kim, Sung Giu Jin, Yu Seok Youn, Kyung Taek Oh, Dong Xun Li, Chul Soon Yong, Jong Oh Kim, Kyeong Soo Kim, Han-Gon Choi: Development of a novel celecoxib-loaded nanosuspension using a wet media milling process
doi: 10.1691/ph.2018.8035 (pp. 498-502)

Yixian Liu, Yafeng Wang, Youmei Peng, Bingjie Liu, Fang Ma, Jinhua Jiang, Qingduan Wang, Junbiao Chang: Effects of the antiretroviral drug 2’-deoxy-2’β-fluoro-4’-azidocytidine (FNC) on P-gp, MRP2 and BCRP expressions and functions
doi: 10.1691/ph.2018.8555 (pp. 503-507)

Wei You, Zhiming Wu, Fei Ye, Xiangqi Wu: Cardamonin protects against adverse cardiac remodeling through mTORC1 inhibition in mice with myocardial infarction
doi: 10.1691/ph.2018.8600 (pp. 508-512)

Zhenglei Xu, Bihong Liao, Ru Zhang, Yingxue Li, Li Mei, Lisheng Wang: Downregulation of microRNA-128-3p protects human esophageal squamous Het-1A cells from hydrochloric acid-induced cell injury by targeting E2F3
doi: 10.1691/ph.2018.8554 (pp. 513-518)

Sugino Y, Kugawa F: Effect of miR-433-3p and miR-883b-5p on murine CYP 3A family enzymes in AML12 cells
doi: 10.1691/ph.2018.8530 (pp. 519-525)

Qing-Fang Meng, Xin-Xin Zhang, Zheng Zhang, Wei Chen, Xiao-Li Li, Yan-Jun Wang, Fei-Fei Li, Yan-Bin Li: Therapeutic potential of artesunate in experimental autoimmune myasthenia gravis by upregulated T regulatory cells and regulation of Th1/Th2 cytokines
doi: 10.1691/ph.2018.8516 (pp. 526-532)

Fangyi Long, Weixin Liu, Ping Jia, Huafei Wang, Gang Jiang, Ting Wang: HIF-1α-induced autophagy contributes to cisplatin resistance in ovarian cancer cells
doi: 10.1691/ph.2018.8514 (pp. 533-536)

Cura-Esquivel I, Delgado-Chávez EN, García-Narro JH, Torres-González L, Alarcón-Galván G, Moreno-Peña DP, Esquivel-Figueroa D, Cantú-Machuca DV, Muñoz-Espinosa LE, Garza-Ocañas L, Cordero-Pérez P: Attenuation of pro-inflammatory cytokines and oxidative stress by misoprostol in renal ischemia/reperfusion in rats
doi: 10.1691/ph.2018.8498 (pp. 537-540)

Deng Guolan, Wang Lingli, He Wenyi, Zhou Wei, Chen Baowei, Bing Sen: Anti-inflammatory effects of neferine on LPS-induced human endothelium via MAPK, and NF-κβ pathways
doi: 10.1691/ph.2018.8443 (pp. 541-544)

Ino Y, Tachi T, Ueno A, Otsubo M, Katsuno H, Noguchi Y, Sakai C, Iguchi K, Kawakami C, Fujisaki K, Teramachi H: Clinic-level factors associated with collaboration with community pharmacies in Japan
doi: 10.1691/ph.2018.8542 (pp. 545-552)

Review

Agbo E, Li M-X, Zhao Y, Saahene RO, Zhao J-P, Mbori N-JR, Sun X, Tian G-Z, Wang Y-G: The role of regulation of PTEN gene in signal transduction pathways related to cardiac hypertrophy and chronic heart failure
doi: 10.1691/ph.2018.8531 (pp. 427-432)

Original Articles

Yuanshuai Yang, Sheng Tang, Zhandong Liu, Yanxiang Wang, Jing Pang, Xuefu You, Danqing Song, Yinghong Li, Xi Lu: Synthesis and antibacterial evaluation of sulbactam derivatives against Acinetobacter baumannii
doi: 10.1691/ph.2018.8487 (pp. 433-437)

Fuqiang Zhu, Jian Zhang, Hainimu Xiamuxi, Weiming Chen, Tianwen Hu, Xiaojun Yang, Guanghui Tian, Runyan Ni, Jian Li, Jin Suo, Yuanchao Xie, Jingshan Shen, Haji A Aisa, Yang He: Identification, synthesis, and control of efinaconazole impurities
doi: 10.1691/ph.2018.8059 (pp. 438-441)

Alves Giordani CF, Campanharo S, Ribeiro Wingert N, Maronesi Bueno L, Wittckind Manoel J, Virginia Garcia C, Volpato NM, Scherman Schapoval EE, Steppe M: Determination of sitagliptin in the presence of its organic impurities using Box-Behnken experimental design for robustness assessment
doi: 10.1691/ph.2018.7201 (pp. 442-446)

Xiaofang Liu, Musheng Li, Wanwen Yuan, Yuan Liu, Ying Wang, Yan Wang: Lipid-coated mesoporous silica nanoparticles of hydroxycamptothecin for sustained release and cancer therapy
doi: 10.1691/ph.2018.8065 (pp. 447-453)

Huamei Wang, Huachao Shen, Jie Wang, Lingyan Yao, Deyou Xu, Xinsheng Ding: Expression of Slit2 in neural stem cell differentiation and maturation and its inhibitory effect on axon growth
doi: 10.1691/ph.2018.8497 (pp. 454-458)

Yuan Luo, Yingdi Zhang, Guojun Miu, Yiwen Zhang, Yuanliang Huang: Icariin promotes osteoblast differentiation and inhibits adipogenesis of bone marrow stem cells through activation of Wnt/β-catenin signaling in vivo and in vitro
doi: 10.1691/ph.2018.8494 (pp. 459-464)

Wenxue Ma, Yawen Yao, Yuyan Gu, Fang Li, Jiaxuan Cai, Baozhu He, Qiuyan Chen, Jian Fang, Zizhang Ouyang: Simvastatin reduces pentraxin 3 expression and secretion in human endothelial cells
doi: 10.1691/ph.2018.8479 (pp. 465-468)

Yi Zhang, Qi Zhou, Hua Yu, Wenbiao Liao, Chao Song: Sox2 silencing effects on proliferation and apoptosis of bladder cancer cells
doi: 10.1691/ph.2018.8450 (pp. 469-473)

Shiwei Lin, Minglei Wei, Wei Zhu: Molecular mechanisms of the anti-inflammatory effect of sinomenine on atopic dermatitis
doi: 10.1691/ph.2018.8047 (pp. 474-476)

Hengyu Tian, Junbo Yang, Zhuochao Xie, Jialin Liu: MiR-486-5p regulates pancreatic β cell function in type 2 diabetes mellitus by targeting PTEN and FOXO1
doi: 10.1691/ph.2018.8526 (pp. 477-481)

Catiċ-Đorđević A, Pavlović D, Stefanović N, Mikov M, Cvetković T, Veličović-Radovanović R: Evaluation of gender-based limited sampling methods for tacrolimus exposure after renal transplantation using the Monte Carlo simulation
doi: 10.1691/ph.2018.8461 (pp. 482-485)

Sato Y, Sumimoto T, Tsushita H, Nakahara R, Matsumoto H, Itoh H: Filgrastim biosimilar for neutropenia in gynecological cancer patients receiving chemotherapy: a prospective, single-center, non-randomized, open trial
doi: 10.1691/ph.2018.8560 (pp. 486-488)

Review

Mingliang Zhu, Kewei Yu, Lu Wang, Shuwen Yu: Contribution of drugs acting on the TLRs/MyD88 signaling pathway on colitis-associated cancer
doi: 10.1691/ph.2018.8388 (pp. 363-368)

Original Articles

Akbas S, Sahin A, Calis S, Oncel H, Capan Y: Characterization of bevacizumab by dynamic light scattering while maintaining its native structure
doi: 10.1691/ph.2018.8024 (pp. 369-374)

Young Seok Ji, In Sook Kim, Tae Kon Kim, Hye Hyun Yoo: Plasma concentration profile of tolterodine and 5-hydroxymethyl tolterodine following transdermal administration of tolterodine in rats
doi: 10.1691/ph.2018.8033 (pp. 375-378)

Wenjing Shao, Yuying Li, Feng Chen, Haiyan Jia, Jia Li, Yan Fu: Long non-coding RNA DLEU1 contributes to the development of endometrial cancer by sponging miR-490 to regulate SP1 expression
doi: 10.1691/ph.2018.8352 (pp. 379-385)

Weiguo Zhang, Bin Qiao, Junli Fan: Overexpression of miR-4443 promotes the resistance of non-small cell lung cancer cells to epirubicin by targeting INPP4A and regulating the activation of JAK2/STAT3 pathway
doi: 10.1691/ph.2018.8313 (pp. 386-392)

Shimizu Y, Mashima-Nemoto T, Hazawa M, Taira Y, Taira I, Ishida I, Isoda K: The hepatoprotective effect of lycopene on Con A-induced liver injury in mice
doi: 10.1691/ph.2018.84737 (pp. 393-395)

Yang Wang, Qi Ni, Qing Ye, Fang Liu, Zhiren Fu, Quanxing Wang: Tanshinone llA activates autophagy to reduce liver ischemia-reperfusion injury by MEK/ERK/mTOR pathway
doi: 10.1691/ph.2018.7509 (pp. 396-401)

Wei-Hua Wang, Jie Chen, Bu-Rong Zhang, Shuai-Jun Lu, Feng Wang, Lan Peng, Jin-Hua Dai, Yi-Zhe Sun: Curcumin inhibits proliferation and enhances apoptosis in A549 cells by downregulating IncRNA UCA1
doi: 10.1691/ph.2018.8402 (pp. 402-407)

Juan Li, Aihua Li, Min Li, Yanhua Liu, Wei Zhao, Dongxue Gao: Ginkgolic acid exerts an anti-inflammatory effect in human umbilical vein endothelial cells induced by ox-LDL
doi: 10.1691/ph.2018.8397 (pp. 408-412)

Yi-Tao Duan, Xiao-Ang Yang, Lian-Ying Fang, Jin-Han Wang, Qiang Liu: Anti-proliferative and anti-invasive effects of garcinol from Garcinia indica on gallbladder carcinoma cells
doi: 10.1691/ph.2018.8366 (pp. 413-417)

Dan Guo, Dangui Chen, Bing Chen: Acute lymphoblastic leukemia in a patient with lgG4-related disease
doi: 10.1691/ph.2018.8416 (pp. 418-421)

Nakashima T, Koido K, Baba H, Otsuka R, Okinaka K, Sano T, Nishigaki R, Hashimoto H, Otsuka T, Eskai M, Terakado H: Contribution of pharmacists with expertise in infectious diseases to appropriate individualized vancomycin dosing
doi: 10.1691/ph.2018.8427 (pp. 422-424)

Review

Ohkura N, Atsumi G, Ohnishi K, Baba K, Taniguchi M: Possible antithrombotic effects of Angelica keiskei (Ashitaba)
doi: 10.1691/ph.2018.8370 (pp. 315-317)

Original articles

Zhengao Sun, Jingyan Song, Xingxing Zhang, Aijuan Wang, Ying Guo, Yi Yang, Xiaoming Wang, Kaiyue Xu, Jifeng Deng: Novel SWATHTM technology for follicular fluid metabolomics in patients with endometriosis
doi: 10.1691/ph.2018.7193 (pp.318-323)

Jie Cao, Yu Li, Yan Du, Yu-jin Wang, Bin Wu, Juan Jia, Zhi-wen Wei, Ke-ming Yun, Wu Liang, Ying-yuan Wang, Jun-hong Sun: Pharmacokinetics of meperidine (pethidine) in rabbit oral fluid: correlation with plasma concentrations after controlled administration
doi: 10.1691/ph.2018.8014 (pp. 324-328)

Sanaz Darbalaei, Xinlin Zhang, Nanxi Wang, Yanjie Qin, Xuemei Han, Ying Rang, Xuejia Zhai, Yongning Lu: Effects of aprepitant on the pharmacokinetics of imatinib and its main metabolite in rats
doi: 10.1691/ph.2018.7335 (pp. 329-334)

Ying Zhao, Ling Wang, Xueying Zhai, Tao Cui, Guijiang Wang, Qijun Pang: The effect of biochanin A on cell growth, apoptosis, and migration in osteosarcoma cells
doi: 10.1691/ph.2018.7351 (pp. 335-341)

Meng Zhang, Hui Tian, Rongrong Li, Wenlong Yan, Rongxue Xu: MicroRNA-4286 promotes esophageal carcinoma development by targeting INPP4A to evoke the JAK2/STAT3 pathway activation
doi: 10.1691/ph.2018.7339 (pp. 342-348)

Liang Qin, Shuxia Fan, Rongbo Jia, Yongxuan Liu: Ginsenoside Rg1 protects cardiomyocytes from hypoxia-induced injury through the Pl3K/AKT/mTOR pathway
doi: 10.1691/ph.2018.8329 (pp. 349-355)

Kose E, An T, Kikkawa A: Assessment of oral anticoagulation control at pharmacist-managed clinics: A retrospective cohort study
doi: 10.1691/ph.2018.8322 (pp. 356-360)

Review

Savelli M, Roche M, Curti C, Bornet C, Rathelot P, Montana M, Vanelle P: Methods to control anticancer chemotherapy preparations ranked by risk analysis
doi: 10.1691/ph.2018.7205 (pp. 251-259)

Original articles

Knoth H, Ihme S, Oertel R, Matthes A, Ritter C: Determination of the contamination by azole antimycotics in hospital and house sewage – a pilot project for the city of Dresden
doi: 10.1691/ph.2018.8364 (pp.260-263)

Shoa-Fen Lin, Su Liu, Hong-Man Xue, Jun-Bin Huang, Jian Wang, Qi-Hui Chen, Bi-Hong Zhang, Chun Chen: Comparison of two dosages of rabbit antithymocyte globulin (r-ATG) in treating children with severe aplastic anemia
doi: 10.1691/ph.2018.7353 (pp. 264-268)

Shu-Hong Dong, Xing Wang, San-Chun Tian, Neng-Qian Ma, Xin-Yang Zhang, Yapeng Liu, Bao-Lai Zhang, Yong-Jie Wu: Arginine methyltransferase inhibitor 1 exhibits antitumor effects against cervical cancer in vitro and in vivo
doi: 10.1691/ph.2018.8365 (pp. 269-273)

Huaiqiu Cai, Qingan Liu, Xiaoqiu Dong, Yawen Cai, Jinlai Yao, Yue Liu: Plasma preptin levels are decreased in patients with essential hypertension
doi: 10.1691/ph.2018.7347 (pp. 274-278)

Juan Chen, Qi-Biao Su, Yu-Qian Tao, Jia-Ming Qin, Yi Zhou, Shan Zhou, Hong-Liang Li, Zhuo-Jia Chen, Ya-Fang Zhou, Lie-Min Zhou, Xue-Ding Wang, Min Huang: ABCC2 rs2273697 is associated with valproic acid concentrations in patients with epilepsy on valproic acid monotherapy
doi: 10.1691/ph.2018.7344 (pp. 279-282)

Jun-Xia Li, Yan-Ping Bi, Jing Wang, Xue Yang, Yan-Fang Tian, Zhong-Fang Sun: JTC-801 inhibits the proliferation and metastasis of ovarian cancer cell SKOV3 through inhibition of the Pl3K – AKT signaling pathway
doi: 10.1691/ph.2018.7326 (pp. 283-287)

Zhiying Luo, Rong Liu, Bao Sun, Xinming Zhou, Zhaoqian Liu, Honghao Zhou, Heng Xu, Xi Li, Wei Zhang: Identification of gene modules associated with warfarin dosage by a genome-wide DNA methylation study
doi: 10.1691/ph.2018.7319 (pp. 288-293)

Zhaohui Li, Jia Wu, Lei Sheng: Ibrutinib improves the development of acute lymphoblastic leukemia by activating endoplasmic reticulum stress-induced cell death
doi: 10.1691/ph.2018.8306 (pp. 294-299)

Yonghwa Lee, Lichao Liu, Yongsub Yi: Inhibitory effect of berberine from Coptidis rhizoma on melanin synthesis of murine malignant melanoma
doi: 10.1691/ph.2018.7953 (pp. 300-303)

Uchida M, Nakamura T, Makihara Y, Suetsugu K, Ikesue H, Mori Y, Kato K, Shiratsuchi M, Hosohata K, Miyamoto T, Akashi K: Comparison of antiemetic effects of granisetron and palonosetron in patients receiving bendamustine-based chemotherapy
doi: 10.1691/ph.2018.7948 (pp. 304-308)

Iwai M, Ito D, Asano H, Adachi S, Okada K, Kimura M, Usami E, Matsuo K, Yoshimura T, Teramachi H: Evaluation of the safety of ramucirumab in Japanese patients with advanced gastric cancer
doi: 10.1691/ph.2018.7355 (pp. 309-312)

Review

Poljak Z, Hulin I, Maruscakova L, Mladosievicova B: Are GnRH and FSH potentially damaging factors in the cardiovascular system?
doi: 10.1691/ph.2018.7992 (pp. 187-190)

Original articles

Haidar S, Jabbour M, Al-Khayat MA, Aichele D, Jose J: Synthesis and biological evaluation of novel 2 (4`-hydroxynaphthyl) chromen-4-one as a CK2 inhibitor
doi: 10.1691/ph.2018.7971 (pp.191-195)

Uriel M, Gómez-Rincón C, Marro D: Stability of regularly prescribed oral liquids formulated with SyrSpend® SF
doi: 10.1691/ph.2018.7008 (pp. 196-201)

Li Xiao, Yu Cao, Yang Wang, Xin Lai, Ke-Qin Gao, Pei Du, Bi-Kui Zhang, Su-Jie Jia: Aberrant histone modifications of global histone and MCP-1 promoter in CD14+ monocytes from patients with coronary artery disease
doi: 10.1691/ph.2018.7342 (pp. 202-206)

Liu Bo-Qiang, Zhang Si-Tong, Lin Zu-Yuan, Nie Wan-Yun, Chen Bin, Lu Yuan, Li Xuyun, Mao Liangen, Chen You-Chao, Yin Xin-Zhen, Chen Zhong, Ying Xiao-Ying, Hu Wei-Wei: Safranal carried by nanostructured lipid vehicles inhibits generalized epilepsy in mice
doi: 10.1691/ph.2018.7310 (pp. 207-210)

Jian Gao, Yue Yuan, Bo Hu, Yuqing Chen: PDX1 transfection induces human adipose derived stem cells differentiation into islet-like cells: what is the benefit for diabetic rats?
doi: 10.1691/ph.2018.7993 (pp. 213-217)

Rui Han, Shixin Li: Regorafenib delays the proliferation of hepatocellular carcinoma by inducing autophagy
doi: 10.1691/ph.2018.7988 (pp. 218-222)

Wei Li, Linhai Wang, Yanhong Liu, Yan Li, Shirong Yu: Efficacy of entecavir-based rescue therapy in lamivudine-resistant chronic hepatitis B patients in China: a retrospective study
doi: 10.1691/ph.2018.7982 (pp. 223-227)

Jie Zhang, Hua Kang, Lifang Wang, Xiaoyan Zhao, Li He: Chrysophanol ameliorates high-fat diet-induced obesity and inflammation in neonatal rats
doi: 10.1691/ph.2018.7980 (pp. 228-233)

Usami E, Kimura M, Furukawa K, Teramachi H, Yoshimura T: Controllable vitamin K deficiency under high-dose oral menatetrenone administration – a case report
doi: 10.1691/ph.2018.7994 (pp. 234-236)

Mansoor K, Qadan F, Schmidt M: Hamamelis virginiana L. leaf extract suppositories in the treatment of hemorrhoids: non-interventional trial and stability study
doi: 10.1691/ph.2018.7942 (pp. 237-240)

Moustafa ES, Swilam NF, Ghanem OB, Hashem AN, Nawwar MA, Lindequist U, Linscheid MW: A coumarin with an unusual structure from Cuphea ignea, its cytotoxicity and antioxidant activities
doi: 10.1691/ph.2018.7946 (pp. 241-243)

Schmidt M, Gross D, Westemeier J: Karl Blumenreuter (1881-1969): Himmler’s chief pharmacist and medical supply quartermaster of the SS
doi: 10.1691/ph.2018.7178 (pp. 244-247)

Original articles

Min Gao, JunHua He, WeiDong Xu, XiaoPing Lai, Fen Liu, GuoGang Tu: Synthesis and molecular simulation study of furoic peptidomimetic derivatives as potent aminopeptidase N inhibitors
doi: 10.1691/ph.2018.7911 (pp. 123-127)

von Zuben ES, Oliveira AG, Chorilli M, Scarpa MV: Development and validation of a rapid reverse-phase HPLC method for the determination of methotrexate from nanostructured liquid crystalline systems
doi: 10.1691/ph.2018.7140 (pp. 128-132)

Petrilli R, Eloy JO, Paschoal JAR, Lopez RFV: Quantification of 5-FU in skin samples for the development of new delivery systems for topical cancer treatment
doi: 10.1691/ph.2018.7138 (pp. 133-138)

du Preez JL, Aucamp ME, Burger C, Gerber M, Viljoen JM, van Zyl L, du Plessis J: Development and validation of the simultaneous determination of artemisone, clofazimine and decoquinate with HPLC
doi: 10.1691/ph.2018.7127 (pp. 139-142)

Alhazmi HA: Measurement of interaction behavior of six biologically important noble metal ions with the iron(III) binding protein, apo-transferrin, using mobility-shift affinity electrophoresis
doi: 10.1691/ph.2018.7179 (pp. 143-149)

Hao Wang, Mingxia Zhang, Guoping Sun: Long non-coding RNA NEAT1 regulates the proliferation, migration and invasion of gastric cancer cells via targeting miR-335-5p/ROCK1 axis
doi: 10.1691/ph.2018.7877 (pp. 150-155)

Qifei Wang, Guangzhen Wu, Xiangyu Che, Quanlin Li, Zhwei Zhang, Qizhen Tang: Sorafenib induces renal cell carcinoma apoptosis via upregulating activating transcription factor 4
doi: 10.1691/ph.2018.7855 (pp. 156-160)

Niki K, Okamoto Y, Nakajima S, Uejima E: The analgesic effect of rescue administration of intravenous acetaminophen in cancer patients may be associated with sex and opioid dose, and the effect would appear to patients administered under 45 mg/day opioid (oral morphine equivalents)
doi: 10.1691/ph.2018.7878 (pp. 161-164)

Isoda K, Nozawa T, Taira Y, Taira I, Shimizu Y, Ishida I: Effects of surface charge and palladium on hepatic and kidney injury induced by polystyrene nanoparticles co-administered to mice with paraquat and cisplatin
doi: 10.1691/ph.2018.7937 (pp. 165-168)

Zhou Hong, Juan Li, Sangita Biswas, Cheng-Shuai Jiang, Yu Huang, Tao Sun, Yang Niu, Jian-Qiang Yu, Wei-Qi Li, Yao Yao: Ramosissimin, a new flavonol from Tararix ramosissima, induces apoptosis in rheumatoid arthritis fibroblast-like synoviocytes
doi: 10.1691/ph.2018.7890 (pp. 169-173)

Kawachi S, Shinoda Y, Kimura M, Usami E, Yoshimura T: Risk factors for severe neutropenia induced by combination therapy of S-1 and cisplatin in patients with advanced/recurrent gastric cancer
doi: 10.1691/ph.2018.7902 (pp. 174-177)

Yasue F, Kimura M, Usami E, Iwai, M, Go M, Kawachi S, Mitsuoka M, Ikeda Y, Yoshimura T: Risk factors contributing to the development of neutropenia in patients receiving oral trifluridine-tipiracil (TAS-102) chemotherapy for advanced/recurrent colorectal cancer
doi: 10.1691/ph.2018.7908 (pp. 178-181)

Lauze S, Maurina B, Sidlovska V: The impact of the Baltic Germans’ emigration on the pharmaceutical sector in Latvia (1939-1940)
doi: 10.1691/ph.2018.7164 (pp. 182-184)

Original articles

Al-Gousous J, Langguth P: A time-scaled convolution approach to construct IVIVC for enteric-coated acetylsalicylic acid tablets
doi: 10.1691/ph.2018.7136 (pp. 67-69)

Cunchun Dai, Shaoqi Qu, Ruili Zhang, Li Zhao, Yuwen Li, Jiajia Zhu, Chunmei Wang, Hui Guo, Zhihui Hao: Development and analytical characterization of a new antiparasitic fenbendazole compound tablet and pharmacokinetic investigations after its oral administration to dogs
doi: 10.1691/ph.2018.7123 (pp. 70-75)

Hagesaether E: Altered drug release from Orfiril® long following ethanol consumption – extent and consequences
doi: 10.1691/ph.2018.7096 (pp. 76-79)

Weihong Zhu, Xinzhan Mao, Wanchun Wang, You Chen, Ding Li, Hui Li, Pengcheng Dou: Anti-ganglioside GD2 monoclonal antibody synergizes with cisplatin to induce endoplasmic reticulum-associated apoptosis in osteosarcoma cells
doi: 10.1691/ph.2018.7836 (pp. 80-86)

Jiang ZM, Qiu HB, Wang SQ, Guo J, Yang ZW, Zhou SB: Ganoderic acid A potentiates the antioxidant effect and protection of mitochondrial membranes and reduces the apoptosis rate in primary hippocampal neurons in magnesium free medium
doi: 10.1691/ph.2018.7108 (pp. 87-91)

Deqing Sun, Aiying Xue, Xia Xue, Manru Ren, Jing Wu, Rongmei Wang: Acetylpuerarin protects against OGD-induced cell injury in BV2 microglia by inhibiting HMGB1 release
doi: 10.1691/ph.2018.7819 (pp. 92-97)

Fan-Fang Tie, Guang-Xiang Luan, Wen-Na Zhou, Zhen-Hua Wang, Xiao-Bing Shi, Gang Li, Hong-Lun Wang: Effects of the oligostilbenes from Iris lactea Pall. var. chinensis (Fisch.) Koidz on the adipocytes differentiation of 3T3-L1 cells
doi: 10.1691/ph.2018.7844 (pp. 98-103)

Kawami M, Yamada Y, Issarachot O, Junyaprasert VB, Yumoto R, Takano M: P-gp modulating effect of Azadirachta indica extract in multidrug-resistant cancer cell lines
doi: 10.1691/ph.2018.7116 (pp. 104-109)

Todo M, Ueda S, Osaki A, Sugitani I, Takahashi T, Takahashi M, Makabe H, Saeki T, Itoh Y: Improvement of treatment outcomes after implementation of comprehensive pharmaceutical care in breast cancer patients receiving everolimus and exemestane
doi: 10.1691/ph.2018.7837 (pp. 110-114)

Kimura M, Wai M, Usami E, Teramachi H, Yoshimura T: Prognostic factors in patients with advanced and recurrent colorectal cancer receiving last-line chemotherapy
doi: 10.1691/ph.2018.7832 (pp. 115-119)

Original articles

Kono Y, Iwasaki A, Fujita T: Effect of surface charge, particle size, and modification by polyethylene glycol of liposomes on their association with Caco-2 cells across an unstirred water layer
doi: 10.1691/ph.2018.7110 (pp. 3-8)

Alkrad JA, Alruby AS: Nonionic microemulsions for oral and transdermal delivery of gentamicin
doi: 10.1691/ph.2018.7098 (pp. 9-15)

Nemes D, Ujhelyi Z, Arany P, Pető A, Fehér P, Váradi J, Fenyvesi F, Vecsernyés M, Bácskay I: Biocompatibility investigation of different pharmaceutical excipients used in liquid dosage forms
doi: 10.1691/ph.2018.7095 (pp. 16-18)

Otręba M, Buszman E: Perphenazine and prochlorperazine induce concentration-dependent loss in human glioblastoma cells viability
doi: 10.1691/ph.2018.7806 (pp. 19-21)

Honma S, Kouno K, Takasaka S, Mitazaki S, Abe S, Kikuchi H, Oshima Y, Yoshida M: Effect of brefelamide on proliferation of 1321N1 human astrocytoma cells induced by glial cell line-derived neurotrophic factor
doi: 10.1691/ph.2018.7786 (pp. 22-28)

Yuyu Huang, Hongwu Wang, Yanhui Wang, Xiaohui Peng, Jing Li, Wenlong Gu, Ting He, Minjun Chen: Regulation and mechanism of miR-146 on renal ischemia reperfusion injury
doi: 10.1691/ph.2018.7776 (pp. 29-34)

Isawa M, Tashiro R, Naruse C, Yamaguchi Y, Itoh H, Nishimura T, Tomi M, Shimada H, Saito H, Mochizuki M, Nakashima E: Effect of serotonin transporter genotype on self-reported efficacy and activity changes of brain prefrontal area in response to placebo
doi: 10.1691/ph.2018.7740 (pp. 35-41)

Yuqiang Shan, Wencheng Kong, Akao Zhu, Panpan Yu, Qi Xie, Sixin Zheng, Huicheng Jin: Long noncoding RNA CCAL promotes gastric cancer cell proliferation and migration in a Myc dependent way
doi: 10.1691/ph.2018.7721 (pp. 42-48)

Yongwei Li, Zhengfei Shan, Bin Yang, Diandong Yang, Changping Men, Yuanshan Cui, Jitao Wu: LncRNA HULC promotes epithelial and smooth-muscle-like differentiation of adipose-derived stem cells by upregulation of BMP9
doi: 10.1691/ph.2018.7634 (pp. 49-55)

Starbek Zorko M, Štrukelj B, Švajger U, Kreft S, Lunder T: Efficacy of a polyphenolic extract from silver fir (Abies alba) bark on psoriasis: a randomised, double-blind, placebo-controlled trial
doi: 10.1691/ph.2018.7741 (pp. 56-60)

Hashim AN, Swilam NF, Moustafa ES, Bakry SM, Labib RM, Barakat HH, Singab AB, Linscheid MW, Nawwar MA: A cytotoxic flavonol glycoside from Melaleuca leucadendra leaves extract with immunostimulant activity
doi: 10.1691/ph.2018.7785 (pp. 61-64)